DE3106984C2 - - Google Patents

Info

Publication number
DE3106984C2
DE3106984C2 DE3106984A DE3106984A DE3106984C2 DE 3106984 C2 DE3106984 C2 DE 3106984C2 DE 3106984 A DE3106984 A DE 3106984A DE 3106984 A DE3106984 A DE 3106984A DE 3106984 C2 DE3106984 C2 DE 3106984C2
Authority
DE
Germany
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3106984A
Other versions
DE3106984A1 (de
Inventor
Isao Kaetsu
Masaru Takasaki Gunma Jp Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Atomic Energy Agency
Original Assignee
Japan Atomic Energy Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Atomic Energy Research Institute filed Critical Japan Atomic Energy Research Institute
Publication of DE3106984A1 publication Critical patent/DE3106984A1/de
Application granted granted Critical
Publication of DE3106984C2 publication Critical patent/DE3106984C2/de
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • Y10T428/2998Coated including synthetic resin or polymer
DE19813106984 1980-02-27 1981-02-25 Verfahren zur herstellung eines mehrschichtigen verbundstoffs mit langzeit-freigabe Granted DE3106984A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55023878A JPS5911563B2 (ja) 1980-02-27 1980-02-27 多層構造の徐放性複合体を製造する方法

Publications (2)

Publication Number Publication Date
DE3106984A1 DE3106984A1 (de) 1982-02-18
DE3106984C2 true DE3106984C2 (de) 1987-04-02

Family

ID=12122702

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813106984 Granted DE3106984A1 (de) 1980-02-27 1981-02-25 Verfahren zur herstellung eines mehrschichtigen verbundstoffs mit langzeit-freigabe

Country Status (3)

Country Link
US (1) US4359483A (de)
JP (1) JPS5911563B2 (de)
DE (1) DE3106984A1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5839618A (ja) * 1981-09-04 1983-03-08 Chugai Pharmaceut Co Ltd 持続性積層錠剤
JPS58134019A (ja) * 1982-02-05 1983-08-10 Ono Pharmaceut Co Ltd プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法
DE3360633D1 (en) * 1982-02-12 1985-10-03 Unitika Ltd Anti-cancer device
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
DK152744C (da) * 1982-08-13 1988-10-31 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat
JPS59225112A (ja) * 1983-06-07 1984-12-18 Japan Atom Energy Res Inst 徐放性複合体およびその製造法
US4652443A (en) * 1983-06-07 1987-03-24 Japan Atomic Energy Research Institute Slow-release composite and process for producing the same
US4983392A (en) * 1983-11-14 1991-01-08 Bio-Mimetics, Inc. Bioadhesive compositions and methods of treatment therewith
US4795436A (en) * 1983-11-14 1989-01-03 Bio-Mimetics, Inc. Bioadhesive composition and method of treatment therewith
JPH0830004B2 (ja) * 1983-11-14 1996-03-27 コロンビア ラボラトリーズ インコーポレイテッド 生物接着性組成物およびそれにより治療する方法
NL8401362A (nl) * 1984-04-27 1985-11-18 Tno Werkwijze voor het met een polymeer omhullen van deeltjesvormige materialen teneinde de gereguleerde afgifte van deze materialen aan de omgeving mogelijk te maken alsmede aldus verkregen omhuld deeltjesvormig materiaal.
US4778786A (en) * 1985-04-03 1988-10-18 Minnetonka, Inc. Composition for transdermal drug delivery
DE3684446D1 (de) * 1985-12-28 1992-04-23 Sumitomo Pharma Arzneimittel mit verzoegerter stossweiser freisetzung.
JPS62195323A (ja) * 1986-02-24 1987-08-28 Eisai Co Ltd 胃内滞留型粒子
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
FR2604712B1 (fr) * 1986-10-02 1988-12-30 Inst Francais Du Petrole Copolymere acrylate acrylamide a bas poids moleculaire et procede pour empecher au moins en partie la formation de depot de sels issus de milieux aqueux
US4789547A (en) * 1987-06-17 1988-12-06 Warner-Lambert Company Transdermal matrix system
US5236703A (en) * 1987-08-20 1993-08-17 Virex Inc. Polymeric substrates containing povidone-iodine as a control release biologically active agent
WO1989005149A1 (en) * 1987-12-03 1989-06-15 The Liposome Company, Inc. Methyl cellulose pharmaceutical composition
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
JP2571874B2 (ja) * 1989-11-06 1997-01-16 アルカーメス コントロールド セラピューティクス,インコーポレイテッド タンパク質マイクロスフェア組成物
US5248516A (en) * 1989-12-19 1993-09-28 Fmc Corporation Film-forming composition: method of producing same and use for coating pharmaceuticals and foods and the like
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
CA2125284C (en) * 1991-12-05 2000-06-20 Jens-Christian Wunderlich Peroral administration form for peptidic medicaments, in particular insulin
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US7070806B2 (en) * 1992-01-27 2006-07-04 Purdue Pharma Lp Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5573934A (en) * 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
TR199701323T1 (xx) 1995-05-09 1998-02-21 Colorcon Limited Farmas�tik alttabakalar�n elektrostatik olarak kaplanmas� i�in toz kaplama kompozisyonu.
US7008668B2 (en) * 1995-05-09 2006-03-07 Phoqus Pharmaceuticals Limited Powder coating composition for electrostatic coating of pharmaceutical substrates
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
US5851579A (en) * 1996-10-28 1998-12-22 Eastman Chemical Company Aqueous enteric coating compositions
GB9623634D0 (en) * 1996-11-13 1997-01-08 Bpsi Holdings Inc Method and apparatus for the coating of substrates for pharmaceutical use
DE19654468C1 (de) * 1996-12-27 1998-01-22 Lohmann Therapie Syst Lts Extrem flexibles, dermal oder transdermal wirkendes Pflaster und Verfahren zu seiner Herstellung
FR2772615B1 (fr) 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
EP1252887A4 (de) * 2000-01-27 2009-07-29 Mitsubishi Tanabe Pharma Corp Zubereitung mit verlängerter freisetzung und prozess zu deren herstellung
GB0002305D0 (en) * 2000-02-01 2000-03-22 Phoqus Limited Power material for electrostatic application
GB2402895B (en) * 2003-06-18 2006-08-23 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
GB0330171D0 (en) * 2003-12-30 2004-02-04 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates
US20060222677A1 (en) * 2004-01-14 2006-10-05 Bianca Baroli Method of protecting sensitive molecules from a photo-polymerizing environment
GB0407312D0 (en) * 2004-03-31 2004-05-05 Phoqus Pharmaceuticals Ltd Method and apparatus for the application of powder material to substrates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1092611B (de) * 1959-08-11 1960-11-10 Wibio G M B H Verfahren und Vorrichtung zum Herstellen von Mehrschichtendragees
CH582002A5 (de) * 1972-06-09 1976-11-30 Purdue Research Foundation
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
HU174057B (hu) * 1976-09-17 1979-10-28 Richter Gedeon Vegyeszet Sostav dlja pokrytij obespechivajuhhij uregulirovannuju otdachy aktivnogo vehhestva biologicheski aktivnykh preparatov i sposob poluchenija takikh preparatov s uregulirovannoj otdachej aktivnogo vehhestva
US4252786A (en) * 1979-11-16 1981-02-24 E. R. Squibb & Sons, Inc. Controlled release tablet
US4282287A (en) * 1980-01-24 1981-08-04 Giese Roger W Biochemical avidin-biotin multiple-layer system

Also Published As

Publication number Publication date
JPS5911563B2 (ja) 1984-03-16
DE3106984A1 (de) 1982-02-18
JPS56120618A (en) 1981-09-22
US4359483A (en) 1982-11-16

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8330 Complete disclaimer