DE69942777D1 - Leicht zerfallende feste Zubereitung - Google Patents
Leicht zerfallende feste ZubereitungInfo
- Publication number
- DE69942777D1 DE69942777D1 DE69942777T DE69942777T DE69942777D1 DE 69942777 D1 DE69942777 D1 DE 69942777D1 DE 69942777 T DE69942777 T DE 69942777T DE 69942777 T DE69942777 T DE 69942777T DE 69942777 D1 DE69942777 D1 DE 69942777D1
- Authority
- DE
- Germany
- Prior art keywords
- solid preparation
- disintegrating solid
- easily disintegrating
- preparation
- solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007787 solid Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21304998 | 1998-07-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69942777D1 true DE69942777D1 (de) | 2010-10-28 |
Family
ID=16632688
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69942777T Expired - Lifetime DE69942777D1 (de) | 1998-07-28 | 1999-07-27 | Leicht zerfallende feste Zubereitung |
DE69924381T Expired - Lifetime DE69924381T2 (de) | 1998-07-28 | 1999-07-27 | Leicht zerfallende feste zubereitung |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69924381T Expired - Lifetime DE69924381T2 (de) | 1998-07-28 | 1999-07-27 | Leicht zerfallende feste zubereitung |
Country Status (20)
Country | Link |
---|---|
US (4) | US20060182802A1 (de) |
EP (2) | EP1561458B1 (de) |
JP (3) | JP3404648B2 (de) |
KR (1) | KR100536783B1 (de) |
CN (1) | CN1149077C (de) |
AR (2) | AR019935A1 (de) |
AT (2) | ATE481090T1 (de) |
AU (1) | AU4802099A (de) |
CA (3) | CA2525555A1 (de) |
CY (1) | CY1110988T1 (de) |
DE (2) | DE69942777D1 (de) |
DK (2) | DK1561458T3 (de) |
ES (2) | ES2237121T3 (de) |
HK (2) | HK1035501A1 (de) |
MY (2) | MY154010A (de) |
PT (2) | PT1100469E (de) |
SI (1) | SI1100469T1 (de) |
TW (2) | TW585786B (de) |
WO (1) | WO2000006126A1 (de) |
ZA (1) | ZA200100285B (de) |
Families Citing this family (135)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE348601T1 (de) | 1998-05-18 | 2007-01-15 | Takeda Pharmaceutical | Im munde zerfallende tablette enthaltend ein benzimidazole |
EP1561458B1 (de) * | 1998-07-28 | 2010-09-15 | Takeda Pharmaceutical Company Limited | Leicht zerfallende feste Zubereitung |
AU5248900A (en) * | 1999-06-18 | 2001-01-09 | Takeda Chemical Industries Ltd. | Quickly disintegrating solid preparations |
JP2001058944A (ja) * | 1999-06-18 | 2001-03-06 | Takeda Chem Ind Ltd | 速崩壊性固形製剤 |
DE60110666T2 (de) * | 2000-03-17 | 2006-02-02 | Shin-Etsu Chemical Co., Ltd. | Feste Zubereitung enthaltend niedersubstituierte Hydroxypropylcellulose und Herstellungsverfahren |
AU4278301A (en) * | 2000-03-27 | 2001-10-08 | Kyowa Hakko Kogyo Co. Ltd. | Easy-to-take granule |
WO2001076565A1 (fr) * | 2000-04-12 | 2001-10-18 | Banyu Pharmaceutical Co., Ltd. | Compositions et preparations se desintegrant dans la cavite buccale |
US6316029B1 (en) * | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
JP4840549B2 (ja) * | 2000-11-20 | 2011-12-21 | トーアエイヨー株式会社 | 安定な血管拡張剤及びその製造方法 |
SI1341528T1 (sl) * | 2000-12-07 | 2012-05-31 | Nycomed Gmbh | Hitro razpadljiva tableta ki obsega kislinsko labilno aktivno sestavino |
CA2437754C (en) * | 2001-02-15 | 2010-05-18 | Tanabe Seiyaku Co., Ltd. | Tablets quickly disintegrated in oral cavity |
US20030224047A1 (en) * | 2001-02-15 | 2003-12-04 | Franz G. Andrew | Levothyroxine compositions and methods |
WO2002092058A1 (fr) * | 2001-05-15 | 2002-11-21 | Takeda Chemical Industries, Ltd. | Preparation solide se desintegrant rapidement |
ATE508725T1 (de) | 2001-06-20 | 2011-05-15 | Takeda Pharmaceutical | Verfahren zur herstellung von tabletten |
WO2003007968A1 (en) * | 2001-07-17 | 2003-01-30 | Sun Pharmaceutical Industries Ltd. | A cardiotonic composition |
KR20040037138A (ko) * | 2001-09-28 | 2004-05-04 | 가부시키가이샤산와카가쿠켄큐쇼 | 유핵형 속용붕괴성 성형품 |
WO2003032953A1 (fr) | 2001-10-17 | 2003-04-24 | Takeda Chemical Industries, Ltd. | Granules contenant un agent chimique instable en milieu acide, en concentration elevee |
JP4108605B2 (ja) * | 2001-11-13 | 2008-06-25 | 協和醗酵工業株式会社 | アミノ酸含有口腔内速崩壊錠及びその製造方法 |
JP2003238393A (ja) * | 2002-02-15 | 2003-08-27 | Otsuka Pharmaceut Co Ltd | 施錠性が改善された錠剤及びその製造方法 |
DE10209982A1 (de) * | 2002-03-07 | 2003-09-25 | Boehringer Ingelheim Pharma | Oral zu applizierende Darreichungsform für schwerlösliche basische Wirkstoffe |
US20030181488A1 (en) * | 2002-03-07 | 2003-09-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof |
CO5400144A1 (es) * | 2002-03-11 | 2004-05-31 | Novartis Ag | Compuestos organicos |
JP4776229B2 (ja) * | 2002-07-16 | 2011-09-21 | エラン ファーマ インターナショナル,リミティド | 安定なナノ粒子活性物質の液体投与組成物 |
US20040018990A1 (en) * | 2002-07-25 | 2004-01-29 | Harvey Rosner | Treatment of obesity |
ATE482710T1 (de) * | 2002-10-02 | 2010-10-15 | Meiji Seika Kaisha | Antibakterielle medizinische zusammensetzung mit erhöhtem oralem absorptionsvermögen |
UA80991C2 (en) | 2002-10-07 | 2007-11-26 | Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes | |
JP4493970B2 (ja) * | 2002-10-16 | 2010-06-30 | 武田薬品工業株式会社 | 持続性製剤 |
MY148805A (en) | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
EP2596792A1 (de) | 2002-10-16 | 2013-05-29 | Takeda Pharmaceutical Company Limited | Stabile, feste Präparate |
US20050220870A1 (en) * | 2003-02-20 | 2005-10-06 | Bonnie Hepburn | Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid |
EP1759692A3 (de) * | 2003-03-10 | 2007-09-12 | Novartis AG | Geschmacksüberdeckte feste arzneiformen für Tiere |
US8449911B2 (en) | 2003-03-12 | 2013-05-28 | Takeda Pharmaceutical Company Limited | Drug composition having active ingredient adhered at high concentration to spherical core |
US8263126B2 (en) | 2003-06-06 | 2012-09-11 | Ethypharm | Orally-dispersible multilayer tablet |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
CA2531564C (en) * | 2003-07-18 | 2016-01-19 | Santarus, Inc. | Pharmaceutical composition for inhibiting acid secretion |
US7838029B1 (en) | 2003-07-31 | 2010-11-23 | Watson Laboratories, Inc. | Mirtazapine solid dosage forms |
JP4601271B2 (ja) * | 2003-08-01 | 2010-12-22 | 大洋薬品工業株式会社 | 圧縮成形製剤およびその製造方法 |
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CA2546115C (en) * | 2003-11-14 | 2013-01-08 | Ajinomoto Co., Inc. | Solid dispersions or solid dispersion pharmaceutical preparations of phenylalanine derivatives |
JP4767492B2 (ja) * | 2003-12-25 | 2011-09-07 | ライオン株式会社 | 高分子被覆粒子の製造方法、高分子被覆粒子、並びにこれを用いた圧縮成形品 |
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WO2005084648A1 (en) * | 2004-02-27 | 2005-09-15 | Ranbaxy Laboratories Limited | Pharmaceutical compositions comprising candesartan cilexetil |
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US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
ATE493973T1 (de) | 2004-06-04 | 2011-01-15 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
JP2008515786A (ja) * | 2004-10-05 | 2008-05-15 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | プロトンポンプアンタゴニスト用の経口医薬調剤 |
US20080095841A1 (en) * | 2004-10-06 | 2008-04-24 | Eisai R&D Management Co., Ltd. | Pharmaceutical Composition, Method for Producing the Same, and Method for Stabilizing Dihydropyridine Compound in the Pharmaceutical Composition |
WO2006076097A2 (en) * | 2004-12-07 | 2006-07-20 | Nektar Therapeutics | Stable non-crystalline formulation comprising losartan |
ES2371145T3 (es) * | 2005-01-26 | 2011-12-27 | Lek Pharmaceuticals D.D. | Nueva composición farmacéutica que contiene candesartán cilexetilo como sustancia cristalina lipófila. |
JP2008535507A (ja) * | 2005-04-15 | 2008-09-04 | ケメ フード エンジニアリング アーゲー | インスタント製品 |
JP5103173B2 (ja) * | 2005-04-28 | 2012-12-19 | エルメッド エーザイ株式会社 | ジヒドロピリジン系化合物の分解を防止する方法 |
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EP1897558B1 (de) * | 2005-06-09 | 2013-09-04 | Norgine BV | Feste zubereitung mit 2-hexadecyloxy-6-methyl-4h-3,1-benzoxazin-4-on |
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EP1961413A4 (de) * | 2005-07-22 | 2012-07-11 | Mitsubishi Tanabe Pharma Corp | Schnell zerfallende orale tablette |
JP5178195B2 (ja) * | 2005-07-25 | 2013-04-10 | 大塚製薬株式会社 | ピリジン代謝能の測定に有用な経口製剤 |
SI1915137T1 (sl) * | 2005-08-10 | 2013-12-31 | Add Advanced Drug Delivery Technologies, Ltd. | Pripravek z nadzorovanim sproščanjem za peroralno dajanje |
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EP2046285B1 (de) * | 2006-08-04 | 2018-02-21 | Ethypharm | Granulat und oral zerfallende tablette mit oxycodon |
BG109687A (bg) * | 2006-09-26 | 2008-03-31 | Иван ХРИСТОВ | Антиастматично лекарствено средство |
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EP2101738A2 (de) * | 2006-12-21 | 2009-09-23 | Mallinckrodt Inc. | Zusammensetzung und verfahren zur herstellung von im mund zerfallenden tabletten |
TWI488658B (zh) * | 2006-12-26 | 2015-06-21 | Daiichi Sankyo Co Ltd | 溶出性之改善方法 |
WO2008081891A1 (ja) | 2006-12-28 | 2008-07-10 | Takeda Pharmaceutical Company Limited | 口腔内崩壊性固形製剤 |
US20080181932A1 (en) * | 2007-01-30 | 2008-07-31 | Drugtech Corporation | Compositions for oral delivery of pharmaceuticals |
JP3967767B1 (ja) * | 2007-02-08 | 2007-08-29 | 秋山錠剤株式会社 | 口腔内速崩錠の製造方法 |
KR20090119993A (ko) * | 2007-03-13 | 2009-11-23 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 구강내 붕괴정 |
US8679541B2 (en) | 2007-03-14 | 2014-03-25 | Particle Dynamics International, Llc | Spatial arrangement of particles in a drinking device for oral delivery of pharmaceuticals |
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