US3658059A - Inhaler - Google Patents
Inhaler Download PDFInfo
- Publication number
- US3658059A US3658059A US883058A US3658059DA US3658059A US 3658059 A US3658059 A US 3658059A US 883058 A US883058 A US 883058A US 3658059D A US3658059D A US 3658059DA US 3658059 A US3658059 A US 3658059A
- Authority
- US
- United States
- Prior art keywords
- inhaler
- opening
- nozzle
- baffle
- accordance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007788 liquid Substances 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 2
- 230000008016 vaporization Effects 0.000 claims description 2
- 239000000725 suspension Substances 0.000 abstract description 19
- 239000002245 particle Substances 0.000 description 11
- 239000000843 powder Substances 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 241000826860 Trapezium Species 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000002445 nipple Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/06—Respiratory or anaesthetic masks
Definitions
- the present invention relates to inhalers for producing suspensions of liquid or pulverulent materials, and more particularly though not exclusively to such inhalers as comprise a suspension outlet opening which is comparatively large in size in comparison with the jet of the inhaler, and means for adjust-
- One object of the invention is to provide an inhaler of the type described above in which a simple manipulation is sufficient to adjust the quantity of suspension and also the size of the suspended particles during operation as may be required.
- a further object of the invention is to provide an inhaler which provides a finer suspension when the quantity of suspension is reduced.
- the present invention consists in an inhaler for administring a suspension of particles, comprising a nozzle for entraining the particles, and a duct for guiding the particle suspension to a patient for inhalation, the duct defining a suspension outlet opening with a cross-section which is considerably larger than the internal cross-section of the nozzle, and a baffle which is arranged to cooperate with the duct in varying the size of the outlet opening, the centre of the effective opening being moved towards the jet when the opening is increased in size and moved away from it when the baffle is moved to reduce the size ofthe opening.
- the suspension particles become finer with the increase in the distance from the nozzle, since the coarser particle settle more readily. Consequently as the bale is moved so as to bring about an increasing closing of the opening only the fine particle leave the inhaler and, with a suitable construction of the apparatus, fall back into means forv storing the liquid or powder to be inhaled.
- the baffle is arranged to rotate and can be constructedas a cylindrical baffle which is coaxially arranged in a suitable tube forming part of the duct, through which the suspension leaving the nozzle region passes upwards.
- an aperture for the suspension is left in the tube and this aperture can be closed to a greater or lesser extent by the baffle.
- the tube is arranged vertically the deposit ofthe coarser particles occurs to a greater degree so that there is a guarantee that as the opening is closed to a greater and greater extent only fine suspension particles will leave the inhaler.
- the closing edge ofthe baffle can be made helical.
- FIG. 1 is a longitudinal section through the inhaler.
- FIG. 2 is a front view of the upper part of the inhaler in which the suspension outlet opening can be seen with the baffle in the open position ⁇ i FIG. 3 is a similar view with the baffle closed.
- FIG. 4 is a view of the baffle removed from the rest of the inhaler.
- FIG. 5 is a plan view of the baffle looking in the direction of its axes of rotation.
- the inhaler shown in FIG. 1 comprises a base 1, which together with a screwed-on intermediate part 2 forms a handle for holding the inhaler.
- the intermediate part 2 in which the medium 3 to be suspended is contained, the atomising or suspending nozzle 4 is mounted, which is provided with a central air channel 5 and suction channels 6 on both sides of it for l the medium to be suspended.
- a discharge opening 9 at the other end can be closed as desired by a rubber button 10 on an actuating lever l1 so that the compressed air supplied to the inhaler is only forced to pass through the nozzle 4 when the lever 11 is operated. In this manner it is possible to use the inhaler only during actual breathing in. l
- a gas flow deflector l2 which in a conventional manner aids in atomisation.
- a substantially cylindrical tube 13 is screwed which forms a continuation of the intermediate part.
- This tube has-a suspension outlet opening 14 in its side (see FIG. 2), whichhas a cross-section which is large in comparison with the internal cross-section of the nozzle.
- the opening adjoins a breathing mask 15. y
- the tube 13 is closed at its free upper end except for a coaxial hole which is defined by an inwardly projecting lip or neck 16.
- a tubular inlet sleeve 17 is mounted in the lip 16 so that it can rotate and serves for the supply of additional air into the inhaler.
- the baffle 19 is mounted on the sleeve 17 by means of a connecting piece 18 (FIG. 5).
- the baffle 19 surrounds the axis of the ⁇ sleeve 17 concentrically and in developed view has approximately the shape of a right-angle triangle or trapezium. Accordingly the closing edge 20 of the baffle 19 has a helical shape.
- the feature that the closing edge is on the side of the baffle 19 removed from the nozzle 4 is especially important to ensure that the suspension outlet opening 14 is closed in such a manner that its centre moves upwards during the process of closing of the opening. This ensures that on reducing the size of the suspension outlet opening at the end of the movement only the finest particles can leave the device while the coarser particles are deposited adjacent to the nozzle or owing to the reduced gas speed fall back into the liquid or powder with which the inhaler has been charged.
- knurled ring 21 being provided at the outerv end of the suction sleeve 17.
- the baffle 19 is also lrotated so that the suspension outlet opening is closed to a greater and greater extent as can be seen from FIGS. 2 and 3.
- An inhaler for vaporizing and atomizing liquid or pulverulent materials comprising:
- nozzle means communicating with the chamber and the source for entraining the liquid or pulverulent material with the gas
- passage means communicating with the nozzle on one ⁇ end and defining an outlet opening on the other end for directing an entrained mixture to an inhalor
- adjustable baffle means rotatably mounted adjacent the opening and having an inclined, helical closing edge remote from the nozzle and extendable across the opening, whereby the closing edge moves away from the nozzle when the opening is reduced.
- An inhaler in accordance with claim 2 further comprising a sleeve member on which the baffle is mounted for introducing air into the inhaler.
Abstract
An inhaler is provided with a baffle for changing the effective size of the passage for passing the suspension to be inhaled in such a manner that the centre of the effective aperture left by the baffle moves towards the jet of the inhaler when the aperture is increased in size and moves away from it when the aperture is reduced in size.
Description
[451 Apr. 25, 1972 References Cited UNITED STATES PATENTS United States Patent Steil [54] INHALER [72] Inventor:
Emeram Steil, Starnberg, Germany PATENTEDAPR 25 |912 SHEET 1 ur 2 PATENTEDAPRESS?? 3,658,059
INHALER The present invention relates to inhalers for producing suspensions of liquid or pulverulent materials, and more particularly though not exclusively to such inhalers as comprise a suspension outlet opening which is comparatively large in size in comparison with the jet of the inhaler, and means for adjust- One object of the invention is to provide an inhaler of the type described above in which a simple manipulation is sufficient to adjust the quantity of suspension and also the size of the suspended particles during operation as may be required. A further object of the invention is to provide an inhaler which provides a finer suspension when the quantity of suspension is reduced.
The present invention consists in an inhaler for administring a suspension of particles, comprising a nozzle for entraining the particles, and a duct for guiding the particle suspension to a patient for inhalation, the duct defining a suspension outlet opening with a cross-section which is considerably larger than the internal cross-section of the nozzle, and a baffle which is arranged to cooperate with the duct in varying the size of the outlet opening, the centre of the effective opening being moved towards the jet when the opening is increased in size and moved away from it when the baffle is moved to reduce the size ofthe opening.
Generally the suspension particles become finer with the increase in the distance from the nozzle, since the coarser particle settle more readily. Consequently as the bale is moved so as to bring about an increasing closing of the opening only the fine particle leave the inhaler and, with a suitable construction of the apparatus, fall back into means forv storing the liquid or powder to be inhaled.
Preferably the baffle is arranged to rotate and can be constructedas a cylindrical baffle which is coaxially arranged in a suitable tube forming part of the duct, through which the suspension leaving the nozzle region passes upwards. In this case an aperture for the suspension is left in the tube and this aperture can be closed to a greater or lesser extent by the baffle. If the tube is arranged vertically the deposit ofthe coarser particles occurs to a greater degree so that there is a guarantee that as the opening is closed to a greater and greater extent only fine suspension particles will leave the inhaler. In order to ensure that there is a linear relationship between movement of the baffle and change in the size of the vopening the closing edge ofthe baffle can be made helical.
Further details of the invention will be gathered from thefollowing description of a preferred embodiment of it referring to the accompanying drawings.
FIG. 1 is a longitudinal section through the inhaler.
FIG. 2 is a front view of the upper part of the inhaler in which the suspension outlet opening can be seen with the baffle in the open position` i FIG. 3 is a similar view with the baffle closed.
FIG. 4 is a view of the baffle removed from the rest of the inhaler.
FIG. 5 is a plan view of the baffle looking in the direction of its axes of rotation.
The inhaler shown in FIG. 1 comprises a base 1, which together with a screwed-on intermediate part 2 forms a handle for holding the inhaler. In the intermediate part 2, in which the medium 3 to be suspended is contained, the atomising or suspending nozzle 4 is mounted, which is provided with a central air channel 5 and suction channels 6 on both sides of it for l the medium to be suspended.
The air channel 5 i's connected with an air duct v7 of larger cross-section which passes transversely through the base l and is connected with a nipple 8 for a compressed air hose. A discharge opening 9 at the other end can be closed as desired by a rubber button 10 on an actuating lever l1 so that the compressed air supplied to the inhaler is only forced to pass through the nozzle 4 when the lever 11 is operated. In this manner it is possible to use the inhaler only during actual breathing in. l
Directly above the nozzle there is a gas flow deflector l2 which in a conventional manner aids in atomisation.
On the intermediate part 2 a substantially cylindrical tube 13 is screwed which forms a continuation of the intermediate part. This tube has-a suspension outlet opening 14 in its side (see FIG. 2), whichhas a cross-section which is large in comparison with the internal cross-section of the nozzle. The opening adjoins a breathing mask 15. y
The tube 13 is closed at its free upper end except for a coaxial hole which is defined by an inwardly projecting lip or neck 16. A tubular inlet sleeve 17 is mounted in the lip 16 so that it can rotate and serves for the supply of additional air into the inhaler. l
The baffle 19 is mounted on the sleeve 17 by means of a connecting piece 18 (FIG. 5). The baffle 19 surrounds the axis of the `sleeve 17 concentrically and in developed view has approximately the shape of a right-angle triangle or trapezium. Accordingly the closing edge 20 of the baffle 19 has a helical shape.
The feature that the closing edge is on the side of the baffle 19 removed from the nozzle 4 is especially important to ensure that the suspension outlet opening 14 is closed in such a manner that its centre moves upwards during the process of closing of the opening. This ensures that on reducing the size of the suspension outlet opening at the end of the movement only the finest particles can leave the device while the coarser particles are deposited adjacent to the nozzle or owing to the reduced gas speed fall back into the liquid or powder with which the inhaler has been charged.
With the inhaler described it is possible by a simple manipulation not only to adjust the rate of supply of the suspension but also tol regulate the particles size as may be desired, a
, knurled ring 21 being provided at the outerv end of the suction sleeve 17. On rotating the sleeve 17 the baffle 19 is also lrotated so that the suspension outlet opening is closed to a greater and greater extent as can be seen from FIGS. 2 and 3.
It is naturally possible to make modifications in the embodiment ofthe invention specifically described. More particularly the device in accordance with the invention can be used for purposes other than inhalation purposes.
The embodiments of the invention in which an exclusive property or privilege is claimed are as follows:
l'. An inhaler for vaporizing and atomizing liquid or pulverulent materials, comprising:
' a. a chamber for liquid or pulverulent material,
b. a source of` gas under pressure, c. nozzle means communicating with the chamber and the source for entraining the liquid or pulverulent material with the gas, v d. passage means communicating with the nozzle on one `end and defining an outlet opening on the other end for directing an entrained mixture to an inhalor, and
e. adjustable baffle means rotatably mounted adjacent the opening and having an inclined, helical closing edge remote from the nozzle and extendable across the opening, whereby the closing edge moves away from the nozzle when the opening is reduced.
2. An inhaler in accordance with claim l in which the baffle means is coaxially mounted with respect to the passage means and wherein the closing edge cooperates with the openingto define the effective cross-sectional area thereof.
3. An inhaler in accordance with claim 1 in which the passage means is substantially vertical in normal operation.
4. An inhaler in accordance with claim 2 further comprising a sleeve member on which the baffle is mounted for introducing air into the inhaler.
* 1k Ik k
Claims (4)
1. An inhaler for vaporizing and atomizing liquid or pulverulent materials, comprising: a. a chamber for liquid or pulverulent material, b. a source of gas under pressure, c. nozzle means communicating with the chamber and the source for entraining the liquid or pulverulent material with the gas, d. passage means communicating with the nozzle on one end and defining an outlet opening on the other end for directing an entrained mixture to an inhalor, and e. adjustable baffle means rotatably mounted adjacent the opening and having an inclined, helical closing edge remote from the nozzle and extendable across the opening, whereby the closing edge moves away from the nozzle when the opening is reduced.
2. An inhaler in accordance with claim 1 in which the baffle means is coaxially mounted with respect to the passage means and wherein the closing edge cooperates with the opening to define the effective cross-sectional area thereof.
3. An inhaler in accordance with claim 1 in which the passage means is substantially vertical in normal operation.
4. An inhaler in accordance with claim 2 further comprising a sleeve member on which the baffle is mounted for introducing air into the inhaler.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1813993A DE1813993C3 (en) | 1968-12-11 | 1968-12-11 | Device for atomizing and atomizing liquid or powdery substances |
Publications (1)
Publication Number | Publication Date |
---|---|
US3658059A true US3658059A (en) | 1972-04-25 |
Family
ID=5715911
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US883058A Expired - Lifetime US3658059A (en) | 1968-12-11 | 1969-12-08 | Inhaler |
Country Status (5)
Country | Link |
---|---|
US (1) | US3658059A (en) |
AT (1) | AT306224B (en) |
CH (1) | CH513656A (en) |
DE (1) | DE1813993C3 (en) |
GB (1) | GB1283988A (en) |
Cited By (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4454877A (en) * | 1981-05-26 | 1984-06-19 | Andrew Boettner | Portable nebulizer or mist producing device |
US4524769A (en) * | 1981-07-08 | 1985-06-25 | Aktiebolaget Draco | Dosage inhalator |
US4534345A (en) * | 1981-07-08 | 1985-08-13 | Aktiebolaget Draco | Dosage inhalator |
US4566451A (en) * | 1982-07-02 | 1986-01-28 | Plantorgan Werk Heinrich G. E. Christensen Kg | Vapor inhalation device |
US4657007A (en) * | 1982-06-28 | 1987-04-14 | Whittaker General Medical Corporation | Nebulizer |
US4792097A (en) * | 1987-03-31 | 1988-12-20 | Mallinckrodt, Inc. | Non-sputtering nebulizer |
US5062419A (en) * | 1991-01-07 | 1991-11-05 | Rider Donald L | Nebulizer with valved "T" assembly |
WO1992004066A1 (en) * | 1990-09-12 | 1992-03-19 | Hans Bisgaard | An inhaling device |
US5161524A (en) * | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
US5170782A (en) * | 1991-09-12 | 1992-12-15 | Devilbiss Health Care, Inc. | Medicament nebulizer with improved aerosol chamber |
US5186166A (en) * | 1992-03-04 | 1993-02-16 | Riggs John H | Powder nebulizer apparatus and method of nebulization |
US5209225A (en) * | 1991-11-19 | 1993-05-11 | Glenn Joseph G | Flow through nebulizer |
US5235969A (en) * | 1990-08-20 | 1993-08-17 | Intersurgical (Guernsey) Limited | Nebulizer having combined structure for removing particles over two microns |
US5355872A (en) * | 1992-03-04 | 1994-10-18 | Riggs John H | Low flow rate nebulizer apparatus and method of nebulization |
US5392768A (en) * | 1991-03-05 | 1995-02-28 | Aradigm | Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval |
US5394866A (en) * | 1991-03-05 | 1995-03-07 | Aradigm Corporation | Automatic aerosol medication delivery system and methods |
US5404871A (en) * | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
US5450336A (en) * | 1991-03-05 | 1995-09-12 | Aradigm Corporation | Method for correcting the drift offset of a transducer |
US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
US5497764A (en) * | 1991-03-05 | 1996-03-12 | Aradigm Corporation | Medication cassette for an automatic aerosol medication delivery |
US5509404A (en) * | 1994-07-11 | 1996-04-23 | Aradigm Corporation | Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values |
US5549102A (en) * | 1991-11-07 | 1996-08-27 | Paul Ritzau Pari-Werk Gmbh | Nebulizer, especially for application in devices for inhalation therapy |
US5584285A (en) * | 1995-06-07 | 1996-12-17 | Salter Labs | Breathing circuit apparatus for a nebulizer |
US5709202A (en) * | 1993-05-21 | 1998-01-20 | Aradigm Corporation | Intrapulmonary delivery of aerosolized formulations |
WO1997048431A3 (en) * | 1996-06-20 | 1998-03-05 | Aid Medic Ltd | Dispensing system |
US5829435A (en) * | 1997-02-24 | 1998-11-03 | Aradigm Corporation | Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles |
US5954047A (en) * | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
US5983893A (en) * | 1994-12-21 | 1999-11-16 | Astra Aktiebolag | Inhalation device |
US6044841A (en) * | 1997-08-29 | 2000-04-04 | 1263152 Ontario Inc. | Breath actuated nebulizer with valve assembly having a relief piston |
US6062214A (en) * | 1996-10-30 | 2000-05-16 | Bespak Plc | Inhaler for medicament |
US6085741A (en) * | 1995-06-06 | 2000-07-11 | Pari Gmbh Spezialisten Fur Effektive Inhalation | Device for atomisation of fluids |
US20020078951A1 (en) * | 2000-12-22 | 2002-06-27 | Nichols Walter A. | Disposable aerosol generator system and methods for administering the aerosol |
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US20020157663A1 (en) * | 2001-03-20 | 2002-10-31 | Rick Blacker | Nebulizer apparatus and method |
US6475796B1 (en) | 1999-05-20 | 2002-11-05 | Scios, Inc. | Vascular endothelial growth factor variants |
WO2002088317A2 (en) | 2001-05-01 | 2002-11-07 | The Regents Of The University Of California | Fusion molecules and methods for treatment of immune diseases |
US6491233B2 (en) | 2000-12-22 | 2002-12-10 | Chrysalis Technologies Incorporated | Vapor driven aerosol generator and method of use thereof |
US6501052B2 (en) | 2000-12-22 | 2002-12-31 | Chrysalis Technologies Incorporated | Aerosol generator having multiple heating zones and methods of use thereof |
US6551542B1 (en) | 1998-11-16 | 2003-04-22 | Aradigm Corporation | Method of fabricating porous membrane with unique pore structure for aerosolized delivery of drugs |
US6557552B1 (en) | 1998-10-14 | 2003-05-06 | Chrysalis Technologies Incorporated | Aerosol generator and methods of making and using an aerosol generator |
US20030089367A1 (en) * | 2001-11-12 | 2003-05-15 | Riccardo Abate | Device for washing nasal cavities and collecting catarrhal matter |
US6568390B2 (en) | 2001-09-21 | 2003-05-27 | Chrysalis Technologies Incorporated | Dual capillary fluid vaporizing device |
US20030108342A1 (en) * | 2001-12-06 | 2003-06-12 | Sherwood Timothy S. | Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate |
US6612303B1 (en) | 1996-02-13 | 2003-09-02 | 1263152 Ontario Inc. | Nebulizer apparatus and method |
US6640050B2 (en) | 2001-09-21 | 2003-10-28 | Chrysalis Technologies Incorporated | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
US6681998B2 (en) | 2000-12-22 | 2004-01-27 | Chrysalis Technologies Incorporated | Aerosol generator having inductive heater and method of use thereof |
US6681769B2 (en) | 2001-12-06 | 2004-01-27 | Crysalis Technologies Incorporated | Aerosol generator having a multiple path heater arrangement and method of use thereof |
US20040016427A1 (en) * | 2000-04-27 | 2004-01-29 | Byron Peter R. | Method and apparatus for generating an aerosol |
US20040031485A1 (en) * | 2002-08-19 | 2004-02-19 | Andre Rustad | Small volume nebulizer |
US6701922B2 (en) | 2001-12-20 | 2004-03-09 | Chrysalis Technologies Incorporated | Mouthpiece entrainment airflow control for aerosol generators |
US6701921B2 (en) | 2000-12-22 | 2004-03-09 | Chrysalis Technologies Incorporated | Aerosol generator having heater in multilayered composite and method of use thereof |
US20040241800A1 (en) * | 1999-05-20 | 2004-12-02 | Jue Rodney Alan | Vascular endothelial growth factor dimers |
US20050081844A1 (en) * | 2003-08-13 | 2005-04-21 | Jerry Grychowski | Nubulizer apparatus and method |
US6883516B2 (en) | 2000-04-27 | 2005-04-26 | Chrysalis Technologies Incorporated | Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution |
US20050158394A1 (en) * | 2000-02-28 | 2005-07-21 | Vectura Limited | Delivery of oral drugs |
US6994083B2 (en) | 2001-12-21 | 2006-02-07 | Trudell Medical International | Nebulizer apparatus and method |
US20060140595A1 (en) * | 2002-12-12 | 2006-06-29 | Hansgrohe Ag | Device for fragrance generation with a steam production |
US20060171942A1 (en) * | 2005-02-02 | 2006-08-03 | Andrew Saxon | Modified fusion molecules for treatment of allergic disease |
US20070062519A1 (en) * | 2004-02-24 | 2007-03-22 | Boehringer Ingelheim International Gmbh | Nebulizer |
US20070235028A1 (en) * | 2002-05-21 | 2007-10-11 | Trudell Medical International | Visual indicator for an aerosol medication delivery apparatus and system |
US7367334B2 (en) | 2003-08-27 | 2008-05-06 | Philip Morris Usa Inc. | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
USRE40591E1 (en) * | 1994-11-11 | 2008-12-02 | Profile Respiratory Systems Limited | Atomizer |
CN100566677C (en) * | 2003-07-22 | 2009-12-09 | 斯恩蒂斯有限公司 | The intraarticular prosthese |
US20100006096A1 (en) * | 2008-07-13 | 2010-01-14 | Prashant Kakade | Methods and apparatus for delivering aerosolized medication |
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USRE45068E1 (en) | 2000-04-11 | 2014-08-12 | Trudell Medical International | Aerosol delivery apparatus |
US8961992B1 (en) | 2014-04-02 | 2015-02-24 | Tunitas Therapeutics, Inc. | Epsigam fusion protein |
ITVR20130279A1 (en) * | 2013-12-12 | 2015-06-13 | Elettroplastica S P A | DEVICE FOR NEBULIZATION OF SUBSTANCES FOR AEROSOL |
WO2016089981A1 (en) * | 2014-12-04 | 2016-06-09 | Carefusion 2200, Inc. | Breath-actuated nebulizer for medicine inhalation |
US9511202B1 (en) * | 2012-12-04 | 2016-12-06 | Mercury Enterprises, Inc. | Breathing assistance device with nebulizer |
US10036574B2 (en) | 2013-06-28 | 2018-07-31 | British American Tobacco (Investments) Limited | Devices comprising a heat source material and activation chambers for the same |
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US11452823B2 (en) * | 2016-09-02 | 2022-09-27 | Inspirx, Inc. | Breath-enhanced jet nebulizer |
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3043377A1 (en) * | 1980-11-17 | 1982-07-01 | Brugger, Inge, 8130 Starnberg | SPRAYER |
DE3238149C2 (en) * | 1982-10-14 | 1995-07-06 | Brugger Inge Geb Ritzau | Device for atomizing liquids |
DE3612473A1 (en) * | 1986-04-14 | 1987-10-15 | Behindertenzentrum Stuttgart E | Device for atomising liquid or pulverulent substances for the treatment of the airways |
GB2233919A (en) * | 1989-07-12 | 1991-01-23 | Stephen Peter Newman | "Aerosol delivery apparatus" |
GB2334217B (en) * | 1998-02-14 | 2002-10-23 | Thomas Shannon | Medical appliances |
EP3017839A1 (en) | 2014-11-10 | 2016-05-11 | Elettroplastica S.p.A. | A device for nebulising substances for aerosols |
CN109498951A (en) * | 2019-01-18 | 2019-03-22 | 山东大学齐鲁医院(青岛) | A kind of respiration internal medicine oxygen mask convenient for atomized medicine introducing |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US733026A (en) * | 1902-07-11 | 1903-07-07 | Frederick Tagliavia Tanini | Inhaler. |
US2064314A (en) * | 1933-12-28 | 1936-12-15 | Sternau & Co Inc S | Inhaler |
US2202701A (en) * | 1938-12-22 | 1940-05-28 | Riddell Products Ltd | Inhalation apparatus |
US2655918A (en) * | 1950-06-27 | 1953-10-20 | Riddell Products Ltd | Inhalation apparatus |
-
1968
- 1968-12-11 DE DE1813993A patent/DE1813993C3/en not_active Expired
-
1969
- 1969-12-05 CH CH1825969A patent/CH513656A/en not_active IP Right Cessation
- 1969-12-08 US US883058A patent/US3658059A/en not_active Expired - Lifetime
- 1969-12-09 AT AT1146769A patent/AT306224B/en not_active IP Right Cessation
- 1969-12-11 GB GB60615/69A patent/GB1283988A/en not_active Expired
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US733026A (en) * | 1902-07-11 | 1903-07-07 | Frederick Tagliavia Tanini | Inhaler. |
US2064314A (en) * | 1933-12-28 | 1936-12-15 | Sternau & Co Inc S | Inhaler |
US2202701A (en) * | 1938-12-22 | 1940-05-28 | Riddell Products Ltd | Inhalation apparatus |
US2655918A (en) * | 1950-06-27 | 1953-10-20 | Riddell Products Ltd | Inhalation apparatus |
Cited By (172)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4454877A (en) * | 1981-05-26 | 1984-06-19 | Andrew Boettner | Portable nebulizer or mist producing device |
US4524769A (en) * | 1981-07-08 | 1985-06-25 | Aktiebolaget Draco | Dosage inhalator |
US4534345A (en) * | 1981-07-08 | 1985-08-13 | Aktiebolaget Draco | Dosage inhalator |
US4657007A (en) * | 1982-06-28 | 1987-04-14 | Whittaker General Medical Corporation | Nebulizer |
US4566451A (en) * | 1982-07-02 | 1986-01-28 | Plantorgan Werk Heinrich G. E. Christensen Kg | Vapor inhalation device |
US4792097A (en) * | 1987-03-31 | 1988-12-20 | Mallinckrodt, Inc. | Non-sputtering nebulizer |
US5235969A (en) * | 1990-08-20 | 1993-08-17 | Intersurgical (Guernsey) Limited | Nebulizer having combined structure for removing particles over two microns |
WO1992004066A1 (en) * | 1990-09-12 | 1992-03-19 | Hans Bisgaard | An inhaling device |
US5755221A (en) * | 1990-09-12 | 1998-05-26 | Bisgaard; Hans | Aerosol inhaler with piston dump |
US5062419A (en) * | 1991-01-07 | 1991-11-05 | Rider Donald L | Nebulizer with valved "T" assembly |
US5392768A (en) * | 1991-03-05 | 1995-02-28 | Aradigm | Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval |
US5497764A (en) * | 1991-03-05 | 1996-03-12 | Aradigm Corporation | Medication cassette for an automatic aerosol medication delivery |
US5655516A (en) * | 1991-03-05 | 1997-08-12 | Aradigm Corporation | Delivery of aerosol medications for inspiration |
US5622162A (en) * | 1991-03-05 | 1997-04-22 | Aradigm Corporation | Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval |
US5608647A (en) * | 1991-03-05 | 1997-03-04 | Aradigm Corporation | Method for releasing controlled amount of aerosol medication |
US5394866A (en) * | 1991-03-05 | 1995-03-07 | Aradigm Corporation | Automatic aerosol medication delivery system and methods |
US5404871A (en) * | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
US5450336A (en) * | 1991-03-05 | 1995-09-12 | Aradigm Corporation | Method for correcting the drift offset of a transducer |
US5826570A (en) * | 1991-03-05 | 1998-10-27 | Aradigm Corporation | Delivery of aerosol medications for inspiration |
US5743252A (en) * | 1991-03-05 | 1998-04-28 | Aradigm Corporation | Method for releasing controlled amount of aerosol medication |
US5755218A (en) * | 1991-03-05 | 1998-05-26 | Aradigm Corporation | Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval |
US5520166A (en) * | 1991-03-05 | 1996-05-28 | Aradigm Corporation | Medication cassette for an automatic aerosol medication delivery system |
US5542410A (en) * | 1991-03-05 | 1996-08-06 | Aradigm Corporation | Delivery of aeerosol medications for inspiration |
US5161524A (en) * | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
US5170782A (en) * | 1991-09-12 | 1992-12-15 | Devilbiss Health Care, Inc. | Medicament nebulizer with improved aerosol chamber |
US5549102A (en) * | 1991-11-07 | 1996-08-27 | Paul Ritzau Pari-Werk Gmbh | Nebulizer, especially for application in devices for inhalation therapy |
US5209225A (en) * | 1991-11-19 | 1993-05-11 | Glenn Joseph G | Flow through nebulizer |
US5355872A (en) * | 1992-03-04 | 1994-10-18 | Riggs John H | Low flow rate nebulizer apparatus and method of nebulization |
US5186166A (en) * | 1992-03-04 | 1993-02-16 | Riggs John H | Powder nebulizer apparatus and method of nebulization |
US5718222A (en) * | 1993-05-21 | 1998-02-17 | Aradigm Corporation | Disposable package for use in aerosolized delivery of drugs |
US5709202A (en) * | 1993-05-21 | 1998-01-20 | Aradigm Corporation | Intrapulmonary delivery of aerosolized formulations |
US5544646A (en) * | 1993-05-21 | 1996-08-13 | Aradigm Corporation | Systems for the intrapulmonary delivery of aerosolized aqueous formulations |
US5823178A (en) * | 1993-05-21 | 1998-10-20 | Aradigm Corporation | Disposable package for use in aerosolized delivery of drugs |
US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
US6014969A (en) * | 1993-05-21 | 2000-01-18 | Aradigm Corporation | Disposable package for use in aerosolized delivery of antibiotics |
US6123068A (en) * | 1993-05-21 | 2000-09-26 | Aradigm Corporation | Systems for the intrapulmonary delivery of aerosolized aqueous formulations |
US5509404A (en) * | 1994-07-11 | 1996-04-23 | Aradigm Corporation | Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values |
USRE40591E1 (en) * | 1994-11-11 | 2008-12-02 | Profile Respiratory Systems Limited | Atomizer |
USRE42911E1 (en) | 1994-11-11 | 2011-11-15 | Ric Investments, Llc | Atomizer |
US5983893A (en) * | 1994-12-21 | 1999-11-16 | Astra Aktiebolag | Inhalation device |
US6085741A (en) * | 1995-06-06 | 2000-07-11 | Pari Gmbh Spezialisten Fur Effektive Inhalation | Device for atomisation of fluids |
US5584285A (en) * | 1995-06-07 | 1996-12-17 | Salter Labs | Breathing circuit apparatus for a nebulizer |
US6612303B1 (en) | 1996-02-13 | 2003-09-02 | 1263152 Ontario Inc. | Nebulizer apparatus and method |
US20040173209A1 (en) * | 1996-02-13 | 2004-09-09 | Trudell Medical International. | Nebulizer apparatus and method |
US7080643B2 (en) | 1996-02-13 | 2006-07-25 | Trudell Medical Internationl | Nebulizer apparatus and method |
US6748945B2 (en) | 1996-02-13 | 2004-06-15 | Trudell Medical International | Nebulizer apparatus and method |
US20070204864A1 (en) * | 1996-02-13 | 2007-09-06 | Trudell Medical International | Aerosol Delivery Apparatus And Method |
US6644304B2 (en) | 1996-02-13 | 2003-11-11 | 1263152 Ontario Inc. | Nebulizer apparatus and method |
US7634995B2 (en) | 1996-02-13 | 2009-12-22 | Trudell Medical International | Nebulizer apparatus and method |
US8061352B2 (en) | 1996-02-13 | 2011-11-22 | Trudell Medical International | Aerosol delivery apparatus and method |
WO1997048431A3 (en) * | 1996-06-20 | 1998-03-05 | Aid Medic Ltd | Dispensing system |
EP1245244A3 (en) * | 1996-06-20 | 2003-05-21 | Medic-Aid Limited | Dispensing system |
US6062214A (en) * | 1996-10-30 | 2000-05-16 | Bespak Plc | Inhaler for medicament |
US5829435A (en) * | 1997-02-24 | 1998-11-03 | Aradigm Corporation | Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles |
US6450163B1 (en) | 1997-08-29 | 2002-09-17 | Trudell Medical International | Breath actuated nebulizer with valve assembly having a relief piston |
US6044841A (en) * | 1997-08-29 | 2000-04-04 | 1263152 Ontario Inc. | Breath actuated nebulizer with valve assembly having a relief piston |
US5954047A (en) * | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
US6095141A (en) * | 1997-10-17 | 2000-08-01 | Sheffield Pharmaceuticals, Inc. | Methods and apparatus for delivering aerosolized medication |
US6026808A (en) * | 1997-10-17 | 2000-02-22 | Sheffield Pharmaceuticals, Inc. | Methods and apparatus for delivering aerosolized medication |
US6557552B1 (en) | 1998-10-14 | 2003-05-06 | Chrysalis Technologies Incorporated | Aerosol generator and methods of making and using an aerosol generator |
US20040050383A1 (en) * | 1998-10-14 | 2004-03-18 | Cox Kenneth A. | Aerosol generator and methods of making and using an aerosol generator |
US7117867B2 (en) | 1998-10-14 | 2006-10-10 | Philip Morris Usa | Aerosol generator and methods of making and using an aerosol generator |
US6551542B1 (en) | 1998-11-16 | 2003-04-22 | Aradigm Corporation | Method of fabricating porous membrane with unique pore structure for aerosolized delivery of drugs |
US6887848B2 (en) | 1999-05-20 | 2005-05-03 | Scios, Inc. | Vascular endothelial growth factor variants |
US20040241800A1 (en) * | 1999-05-20 | 2004-12-02 | Jue Rodney Alan | Vascular endothelial growth factor dimers |
US20050119165A1 (en) * | 1999-05-20 | 2005-06-02 | Scios, Inc. | Vascular endothelial growth factor dimers |
US6475796B1 (en) | 1999-05-20 | 2002-11-05 | Scios, Inc. | Vascular endothelial growth factor variants |
US20030096754A1 (en) * | 1999-05-20 | 2003-05-22 | Pollitt N. Stephen | Vascular endothelial growth factor variants |
EP1941868A2 (en) | 2000-02-28 | 2008-07-09 | PharmaKodex Limited | Improvements in or relating to the delivery of oral drugs |
US20050158394A1 (en) * | 2000-02-28 | 2005-07-21 | Vectura Limited | Delivery of oral drugs |
USRE45068E1 (en) | 2000-04-11 | 2014-08-12 | Trudell Medical International | Aerosol delivery apparatus |
USRE46050E1 (en) | 2000-04-11 | 2016-07-05 | Trudell Medical International | Aerosol delivery apparatus |
US20040016427A1 (en) * | 2000-04-27 | 2004-01-29 | Byron Peter R. | Method and apparatus for generating an aerosol |
US7128067B2 (en) | 2000-04-27 | 2006-10-31 | Philip Morris Usa Inc. | Method and apparatus for generating an aerosol |
US6883516B2 (en) | 2000-04-27 | 2005-04-26 | Chrysalis Technologies Incorporated | Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution |
US7173222B2 (en) | 2000-12-22 | 2007-02-06 | Philip Morris Usa Inc. | Aerosol generator having temperature controlled heating zone and method of use thereof |
US7163014B2 (en) | 2000-12-22 | 2007-01-16 | Philip Morris Usa Inc. | Disposable inhaler system |
US20040182389A1 (en) * | 2000-12-22 | 2004-09-23 | Sprinkel F. Murphy | Aerosol generator having heater in multilayered composite and method of use thereof |
US7373938B2 (en) | 2000-12-22 | 2008-05-20 | Philip Morris Usa Inc. | Disposable aerosol generator system and methods for administering the aerosol |
US6681998B2 (en) | 2000-12-22 | 2004-01-27 | Chrysalis Technologies Incorporated | Aerosol generator having inductive heater and method of use thereof |
US20040255941A1 (en) * | 2000-12-22 | 2004-12-23 | Chrysalis Technologies Incorporated | Disposable aerosol generator system and methods for administering the aerosol |
US20020078951A1 (en) * | 2000-12-22 | 2002-06-27 | Nichols Walter A. | Disposable aerosol generator system and methods for administering the aerosol |
US6701921B2 (en) | 2000-12-22 | 2004-03-09 | Chrysalis Technologies Incorporated | Aerosol generator having heater in multilayered composite and method of use thereof |
US7077130B2 (en) | 2000-12-22 | 2006-07-18 | Chrysalis Technologies Incorporated | Disposable inhaler system |
WO2002051466A2 (en) | 2000-12-22 | 2002-07-04 | Chrysalis Technologies Incorporated | Disposable aerosol generator system and methods for administering the aerosol |
US6501052B2 (en) | 2000-12-22 | 2002-12-31 | Chrysalis Technologies Incorporated | Aerosol generator having multiple heating zones and methods of use thereof |
US6491233B2 (en) | 2000-12-22 | 2002-12-10 | Chrysalis Technologies Incorporated | Vapor driven aerosol generator and method of use thereof |
US6929003B2 (en) | 2001-03-20 | 2005-08-16 | Trudell Medical International | Nebulizer apparatus and method |
US7131439B2 (en) | 2001-03-20 | 2006-11-07 | Trudell Medical International | Nebulizer apparatus and method |
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US20020157663A1 (en) * | 2001-03-20 | 2002-10-31 | Rick Blacker | Nebulizer apparatus and method |
US9364618B2 (en) | 2001-03-20 | 2016-06-14 | Trudell Medical International | Nebulizer apparatus and method |
EP2335726A1 (en) | 2001-05-01 | 2011-06-22 | The Regents of the University of California | Fusion molecules and methods for treatment of immune diseases |
WO2002088317A2 (en) | 2001-05-01 | 2002-11-07 | The Regents Of The University Of California | Fusion molecules and methods for treatment of immune diseases |
US6568390B2 (en) | 2001-09-21 | 2003-05-27 | Chrysalis Technologies Incorporated | Dual capillary fluid vaporizing device |
US6715487B2 (en) | 2001-09-21 | 2004-04-06 | Chrysalis Technologies Incorporated | Dual capillary fluid vaporizing device |
US6640050B2 (en) | 2001-09-21 | 2003-10-28 | Chrysalis Technologies Incorporated | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
US20030089367A1 (en) * | 2001-11-12 | 2003-05-15 | Riccardo Abate | Device for washing nasal cavities and collecting catarrhal matter |
US7143763B2 (en) * | 2001-11-12 | 2006-12-05 | Flaem Nuova S.P.A. | Device for washing nasal cavities and collecting catarrhal matter |
US6804458B2 (en) | 2001-12-06 | 2004-10-12 | Chrysalis Technologies Incorporated | Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate |
US6681769B2 (en) | 2001-12-06 | 2004-01-27 | Crysalis Technologies Incorporated | Aerosol generator having a multiple path heater arrangement and method of use thereof |
US20030108342A1 (en) * | 2001-12-06 | 2003-06-12 | Sherwood Timothy S. | Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate |
US20040170405A1 (en) * | 2001-12-06 | 2004-09-02 | Chrysalis Technologies Incorporated | Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate |
WO2003049792A1 (en) | 2001-12-07 | 2003-06-19 | Chrysalis Technologies Incorporated | Disposable aerosol generator system and methods for administering the aerosol |
US6701922B2 (en) | 2001-12-20 | 2004-03-09 | Chrysalis Technologies Incorporated | Mouthpiece entrainment airflow control for aerosol generators |
US7568480B2 (en) | 2001-12-21 | 2009-08-04 | Trudell Medical International | Nebulizer apparatus and method |
US8397712B2 (en) | 2001-12-21 | 2013-03-19 | Trudell Medical International | Nebulizer apparatus and method |
US6994083B2 (en) | 2001-12-21 | 2006-02-07 | Trudell Medical International | Nebulizer apparatus and method |
US8844520B2 (en) | 2001-12-21 | 2014-09-30 | Trudell Medical International | Nebulizer apparatus and method |
US7559322B2 (en) | 2001-12-21 | 2009-07-14 | Trudell Medical International | Nebulizer apparatus and method |
US20060213507A1 (en) * | 2001-12-21 | 2006-09-28 | Trudell Medical International | Nebulizer apparatus and method |
US20090272820A1 (en) * | 2001-12-21 | 2009-11-05 | Trudell Medical International | Nebulizer apparatus and method |
US20060157052A1 (en) * | 2001-12-21 | 2006-07-20 | Trudell Medical International | Nebulizer apparatus and method |
US8459252B2 (en) | 2002-05-02 | 2013-06-11 | Pari Innovative Manufacturers, Inc. | Aerosol medication inhalation system |
US9308335B2 (en) | 2002-05-02 | 2016-04-12 | Pre Holding, Inc. | Aerosol medication inhalation system |
US8973571B1 (en) | 2002-05-02 | 2015-03-10 | Pre Holding, Inc. | Aerosol medication inhalation system |
US8550067B2 (en) | 2002-05-21 | 2013-10-08 | Trudell Medical International | Visual indicator for an aerosol medication delivery apparatus and system |
US20070235028A1 (en) * | 2002-05-21 | 2007-10-11 | Trudell Medical International | Visual indicator for an aerosol medication delivery apparatus and system |
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US9700689B2 (en) | 2002-05-21 | 2017-07-11 | Trudell Medical International | Medication delivery apparatus and system and methods for the use and assembly thereof |
US8074642B2 (en) | 2002-05-21 | 2011-12-13 | Trudell Medical International | Visual indicator for an aerosol medication delivery apparatus and system |
US20040031485A1 (en) * | 2002-08-19 | 2004-02-19 | Andre Rustad | Small volume nebulizer |
US7267120B2 (en) | 2002-08-19 | 2007-09-11 | Allegiance Corporation | Small volume nebulizer |
US20060140595A1 (en) * | 2002-12-12 | 2006-06-29 | Hansgrohe Ag | Device for fragrance generation with a steam production |
CN100566677C (en) * | 2003-07-22 | 2009-12-09 | 斯恩蒂斯有限公司 | The intraarticular prosthese |
US7270123B2 (en) | 2003-08-13 | 2007-09-18 | Trudell Medical International | Nebulizer apparatus and method |
US7954487B2 (en) | 2003-08-13 | 2011-06-07 | Trudell Medical International | Nebulizer apparatus and method |
US20050081844A1 (en) * | 2003-08-13 | 2005-04-21 | Jerry Grychowski | Nubulizer apparatus and method |
US20080083407A1 (en) * | 2003-08-13 | 2008-04-10 | Trudell Medical International | Nebulizer Apparatus And Method |
US7367334B2 (en) | 2003-08-27 | 2008-05-06 | Philip Morris Usa Inc. | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
US7571722B2 (en) | 2004-02-24 | 2009-08-11 | Boehringer Ingelheim International Gmbh | Nebulizer |
US20070062519A1 (en) * | 2004-02-24 | 2007-03-22 | Boehringer Ingelheim International Gmbh | Nebulizer |
US7488804B2 (en) | 2005-02-02 | 2009-02-10 | The Regents Of The University Of California | Modified fusion molecules for treatment of allergic disease |
US20090136493A1 (en) * | 2005-02-02 | 2009-05-28 | Andrew Saxon | Modified fusion molecules for treatment of allergic disease |
US20060171942A1 (en) * | 2005-02-02 | 2006-08-03 | Andrew Saxon | Modified fusion molecules for treatment of allergic disease |
US20100006096A1 (en) * | 2008-07-13 | 2010-01-14 | Prashant Kakade | Methods and apparatus for delivering aerosolized medication |
US8517009B2 (en) | 2008-07-13 | 2013-08-27 | Map Pharmaceuticals, Inc. | Methods and apparatus for delivering aerosolized medication |
US9216259B2 (en) | 2008-07-13 | 2015-12-22 | Map Pharmaceuticals, Inc. | Methods and apparatus for delivering aerosolized medication |
US11672279B2 (en) | 2011-09-06 | 2023-06-13 | Nicoventures Trading Limited | Heating smokeable material |
US11241042B2 (en) | 2012-09-25 | 2022-02-08 | Nicoventures Trading Limited | Heating smokeable material |
CN104884110B (en) * | 2012-10-31 | 2018-11-02 | 特鲁德尔医学国际公司 | Atomiser-type appts |
CN104884110A (en) * | 2012-10-31 | 2015-09-02 | 特鲁德尔医学国际公司 | Nebulizer apparatus |
WO2014068387A1 (en) * | 2012-10-31 | 2014-05-08 | Trudell Medical International | Nebulizer apparatus |
US9539408B2 (en) | 2012-10-31 | 2017-01-10 | Trudell Medical International | Nebulizer apparatus |
US10668229B2 (en) | 2012-10-31 | 2020-06-02 | Trude Medical International | Nebulizer apparatus |
US9511202B1 (en) * | 2012-12-04 | 2016-12-06 | Mercury Enterprises, Inc. | Breathing assistance device with nebulizer |
US10036574B2 (en) | 2013-06-28 | 2018-07-31 | British American Tobacco (Investments) Limited | Devices comprising a heat source material and activation chambers for the same |
ITVR20130279A1 (en) * | 2013-12-12 | 2015-06-13 | Elettroplastica S P A | DEVICE FOR NEBULIZATION OF SUBSTANCES FOR AEROSOL |
US9109030B1 (en) | 2014-04-02 | 2015-08-18 | Tunitas Therapeutics, Inc. | Epsigam fusion protein |
US8961992B1 (en) | 2014-04-02 | 2015-02-24 | Tunitas Therapeutics, Inc. | Epsigam fusion protein |
US10542777B2 (en) | 2014-06-27 | 2020-01-28 | British American Tobacco (Investments) Limited | Apparatus for heating or cooling a material contained therein |
WO2016089981A1 (en) * | 2014-12-04 | 2016-06-09 | Carefusion 2200, Inc. | Breath-actuated nebulizer for medicine inhalation |
US11291780B2 (en) | 2014-12-04 | 2022-04-05 | Vyaire Medical Consumables Llc | Breath-actuated nebulizer for medicine inhalation |
US11659863B2 (en) | 2015-08-31 | 2023-05-30 | Nicoventures Trading Limited | Article for use with apparatus for heating smokable material |
US11064725B2 (en) | 2015-08-31 | 2021-07-20 | British American Tobacco (Investments) Limited | Material for use with apparatus for heating smokable material |
US11924930B2 (en) | 2015-08-31 | 2024-03-05 | Nicoventures Trading Limited | Article for use with apparatus for heating smokable material |
US11825870B2 (en) | 2015-10-30 | 2023-11-28 | Nicoventures Trading Limited | Article for use with apparatus for heating smokable material |
US11452313B2 (en) | 2015-10-30 | 2022-09-27 | Nicoventures Trading Limited | Apparatus for heating smokable material |
US10850050B2 (en) | 2016-05-19 | 2020-12-01 | Trudell Medical International | Smart valved holding chamber |
US10786638B2 (en) | 2016-07-08 | 2020-09-29 | Trudell Medical International | Nebulizer apparatus and method |
US11839716B2 (en) | 2016-07-08 | 2023-12-12 | Trudell Medical International | Smart oscillating positive expiratory pressure device |
US11452823B2 (en) * | 2016-09-02 | 2022-09-27 | Inspirx, Inc. | Breath-enhanced jet nebulizer |
US11497867B2 (en) | 2016-12-09 | 2022-11-15 | Trudell Medical International | Smart nebulizer |
RU2771733C2 (en) * | 2017-07-19 | 2022-05-11 | ФЛАЕМ НУОВА С.п.А. | Spraying device for medical mixture |
IT201700082273A1 (en) * | 2017-07-19 | 2019-01-19 | Flaem Nuova Spa | Spray device for a medical mixture |
WO2019016257A1 (en) | 2017-07-19 | 2019-01-24 | Flaem Nuova S.P.A. | Nebulization device for medical mixture |
US11389602B2 (en) * | 2017-07-19 | 2022-07-19 | Flaem Nuova S.P.A. | Nebulization device for medical mixture |
US11666801B2 (en) | 2018-01-04 | 2023-06-06 | Trudell Medical International | Smart oscillating positive expiratory pressure device |
US11712175B2 (en) | 2019-08-27 | 2023-08-01 | Trudell Medical International | Smart oscillating positive expiratory pressure device with feedback indicia |
Also Published As
Publication number | Publication date |
---|---|
CH513656A (en) | 1971-10-15 |
GB1283988A (en) | 1972-08-02 |
DE1813993C3 (en) | 1974-01-24 |
DE1813993A1 (en) | 1970-06-18 |
AT306224B (en) | 1973-03-26 |
DE1813993B2 (en) | 1973-06-28 |
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AS | Assignment |
Owner name: RITZAU PAUL PARI-WERK GMBH 8130 STARNBERG WEST GER Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:PAUL RITZAU PARI BETEILIGUNGS-UND VERWALTUNGSESELLSCHAFTMIT BESCHANKTER HAFTUNG & CO. HOLDING;REEL/FRAME:004361/0345 Effective date: 19841204 Owner name: RITZAU PAUL PARI BETEILIGUNGS- UND VERWALTUNGSGELL Free format text: CHANGE OF NAME;ASSIGNOR:RITZUA PAUL PARI-WERK KG.;REEL/FRAME:004361/0347 Effective date: 19840806 |