WO2014175852A1 - Enteric coated multiparticulate controlled release peppermint oil composition and related methods - Google Patents
Enteric coated multiparticulate controlled release peppermint oil composition and related methods Download PDFInfo
- Publication number
- WO2014175852A1 WO2014175852A1 PCT/US2013/000217 US2013000217W WO2014175852A1 WO 2014175852 A1 WO2014175852 A1 WO 2014175852A1 US 2013000217 W US2013000217 W US 2013000217W WO 2014175852 A1 WO2014175852 A1 WO 2014175852A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cores
- peppermint oil
- multiparticulate composition
- enteric
- multiparticulate
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
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- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/5005—Wall or coating material
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR112015006499A BR112015006499A2 (en) | 2013-04-23 | 2013-09-23 | enteric coated microparticulate controlled release peppermint oil composition and related methods |
JP2015536756A JP5869735B2 (en) | 2013-04-23 | 2013-09-23 | Enteric coated multiparticulate sustained release peppermint oil composition and related methods |
ES13883071.6T ES2616701T3 (en) | 2013-04-23 | 2013-09-23 | Composition of multiparticulate controlled release peppermint oil with enteric coating and related methods |
RU2015136984A RU2606593C1 (en) | 2013-04-23 | 2013-09-23 | Controlled release peppermint oil composition coated with enteric-soluble shell, consisting of multiple particles, and related to it methods |
CA2881992A CA2881992C (en) | 2013-04-23 | 2013-09-23 | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
MX2015005913A MX344705B (en) | 2013-04-23 | 2013-09-23 | Enteric coated multiparticulate controlled release peppermint oil composition and related methods. |
AU2013387678A AU2013387678B2 (en) | 2013-04-23 | 2013-09-23 | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
EP13883071.6A EP2872123B1 (en) | 2013-04-23 | 2013-09-23 | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
CN201380052353.XA CN105263480B (en) | 2013-04-23 | 2013-09-23 | The multiparticulates controlled release mint oil combination object and correlation technique of enteric coating |
KR1020157005776A KR101616679B1 (en) | 2013-04-23 | 2013-09-23 | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361815073P | 2013-04-23 | 2013-04-23 | |
US61/815,073 | 2013-04-23 | ||
US201361880294P | 2013-09-20 | 2013-09-20 | |
US61/880,294 | 2013-09-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2014175852A1 true WO2014175852A1 (en) | 2014-10-30 |
Family
ID=51792243
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2013/061141 WO2014175916A1 (en) | 2013-04-23 | 2013-09-23 | Enteric coated multiparticulate composition with proteinaceous subcoat |
PCT/US2013/000217 WO2014175852A1 (en) | 2013-04-23 | 2013-09-23 | Enteric coated multiparticulate controlled release peppermint oil composition and related methods |
PCT/US2013/061146 WO2014175917A1 (en) | 2013-04-23 | 2013-09-23 | Multiparticulate-menthol formulations and related methods |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2013/061141 WO2014175916A1 (en) | 2013-04-23 | 2013-09-23 | Enteric coated multiparticulate composition with proteinaceous subcoat |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2013/061146 WO2014175917A1 (en) | 2013-04-23 | 2013-09-23 | Multiparticulate-menthol formulations and related methods |
Country Status (21)
Country | Link |
---|---|
US (7) | US8895086B2 (en) |
EP (2) | EP2872123B1 (en) |
JP (3) | JP5869735B2 (en) |
KR (2) | KR101616679B1 (en) |
CN (2) | CN105263480B (en) |
AU (2) | AU2013387678B2 (en) |
BR (2) | BR112015006499A2 (en) |
CA (2) | CA2881992C (en) |
CY (1) | CY1121582T1 (en) |
DK (1) | DK2988824T3 (en) |
ES (2) | ES2706152T3 (en) |
HR (1) | HRP20190210T1 (en) |
HU (1) | HUE042996T2 (en) |
LT (1) | LT2988824T (en) |
MX (2) | MX344705B (en) |
PL (2) | PL2872123T3 (en) |
PT (2) | PT2872123T (en) |
RS (1) | RS58325B1 (en) |
RU (2) | RU2647462C2 (en) |
SI (1) | SI2988824T1 (en) |
WO (3) | WO2014175916A1 (en) |
Cited By (1)
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WO2022148672A1 (en) * | 2021-01-08 | 2022-07-14 | Société des Produits Nestlé S.A. | Oral solid cannabinoid oil composition for treating central nervous system disorders |
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US9532952B2 (en) | 2011-01-28 | 2017-01-03 | Physician's Seal, LLC | Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients |
WO2012103411A2 (en) | 2011-01-28 | 2012-08-02 | Zx Pharma, Llc | Controlled-release melatonin composition and related methods |
DK3305285T3 (en) | 2012-09-26 | 2020-10-26 | Aragon Pharmaceuticals Inc | ANTI-ANDROGENES FOR THE TREATMENT OF NON-METASTATIC CASTRATION RESISTANT PROSTATE CANCER |
CN105263480B (en) * | 2013-04-23 | 2018-08-28 | Zx制药有限责任公司 | The multiparticulates controlled release mint oil combination object and correlation technique of enteric coating |
CN109562137A (en) | 2015-09-01 | 2019-04-02 | 第波生物公司 | For treating the method and composition for reacting the related patient's condition with abnormal inflammatory |
US10588864B2 (en) | 2016-03-11 | 2020-03-17 | Gateway Pharmaceuticals LLC | Pharmaceutical compositions for colon-specific delivery |
CN117482062A (en) | 2016-05-06 | 2024-02-02 | 雀巢产品有限公司 | Valerian compositions and related methods |
KR102568459B1 (en) | 2016-10-26 | 2023-08-22 | 에스엘 주식회사 | The Apparatus For Controlling Vehicle Lamp |
CN107049992A (en) * | 2017-05-31 | 2017-08-18 | 盛林 | A kind of EGCG micro pill capsules and preparation method thereof |
SG11202003402QA (en) | 2017-10-16 | 2020-05-28 | Aragon Pharmaceuticals Inc | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
CN109864982A (en) * | 2019-03-22 | 2019-06-11 | 大连医诺生物股份有限公司 | Epigallo-catechin gallate (EGCG) microcapsule powder and preparation method thereof |
US20230102999A1 (en) | 2020-01-10 | 2023-03-30 | First Wave Bio, Inc. | Deuterated niclosamide |
US20230190684A1 (en) | 2020-03-16 | 2023-06-22 | First Wave Bio, Inc. | Methods of treating covid-19 with a niclosamide compound |
US10980756B1 (en) | 2020-03-16 | 2021-04-20 | First Wave Bio, Inc. | Methods of treatment |
KR102608047B1 (en) * | 2020-12-29 | 2023-12-01 | 주식회사 우제아이엠 | Balanced nutrition included food composition for preventing or improving reflux esophageal disease or functional dyspepsia |
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