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Synonyms

Exanthem subitum; Sixth disease; Exanthem criticum

Definition and Characteristics

Roseola infantum is characterized by high fever that lasts 3–4 days followed by the sudden appearance of rash at defervescence (hence the term “exanthem subitum” meaning “sudden rash”) [1]. The fever has an abrupt onset and the temperature commonly is in the range of 39–40.5°C. Most children are otherwise well and appear to be happy, alert, and playful. However, some children may exhibit periods of restlessness and irritability during times of increased fever. With defervescence, the typical exanthem appears. Characteristically, the rash is rose pink in color, macular, measuring 2–3 mm in diameter (Fig. 1).

Roseola Infantum. Figure 1
figure 1_3347

A 10-month-old infant with roseola infantum. Note the rose-pink macules on the trunk.

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References

  1. Leung AK, Kao CP (2006) Consultant Pediatrician 5:561–564

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  2. Scott LA, Stone MS (2003) Dermatol Online J 9(3):4

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  3. Dockrell DH (2003) J Med Microbiol 52:5–18

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  4. Leach CT (2000) Curr Opin Pediatr 269–274

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  5. Dyer JA (2007) Pediatr Ann 36:21–29

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© 2009 Springer-Verlag GmbH Berlin Heidelberg

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Leung, A.K.C. (2009). Roseola Infantum. In: Lang, F. (eds) Encyclopedia of Molecular Mechanisms of Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29676-8_3347

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