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The Goldfish Genome and Its Utility for Understanding Gene Regulation and Vertebrate Body Morphology

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Zebrafish

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2707))

Abstract

Goldfish, widely viewed as an ornamental fish, is a member of Cyprinidae family and has a very long history in research for both genetics and physiology studies. Among Cyprinidae, the chromosomal locations of orthologs and the amino acid sequences are usually highly conserved. Adult goldfish are 1000 times larger than adult zebrafish (who are in the same family of fishes), which can make it easier to perform several types of experiments compared to their zebrafish cousins. Comparing mutant phenotypes in orthologous genes between goldfish and zebrafish can often be very informative and provide a deeper insight into the gene function than studying the gene in either species alone. Comparative genomics and phenotypic comparisons between goldfish and zebrafish will provide new opportunities for understanding the development and evolution of body forms in the vertebrate lineage.

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Author information

Authors and Affiliations

  1. Laboratory of Functional Genomics, Graduate School of Bioscience, Nagahama Institute of Bioscience and Technology, Nagahama, Japan

    Yoshihiro Omori

  2. Translational and Functional Genomics Branch, National Human Genome Research Institute, Bethesda, MD, USA

    Shawn M. Burgess

Authors
  1. Yoshihiro Omori
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  2. Shawn M. Burgess
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Corresponding authors

Correspondence to Yoshihiro Omori or Shawn M. Burgess .

Editor information

Editors and Affiliations

  1. Department of Pediatrics Children’s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

    James F. Amatruda

  2. Centre for Developmental Neurobiology, MRC Centre for NeuroDevelopmental Disorders, King’s College London, London, UK

    Corinne Houart

  3. Laboratory of Molecular and Developmental Biology, National Institute of Genetics, Mishima, Shizuoka, Japan

    Koichi Kawakami

  4. Duke Regeneration Center, Department of Cell Biology, Duke University Medical Center, Durham, NC, USA

    Kenneth D. Poss

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© 2024 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Omori, Y., Burgess, S.M. (2024). The Goldfish Genome and Its Utility for Understanding Gene Regulation and Vertebrate Body Morphology. In: Amatruda, J.F., Houart, C., Kawakami, K., Poss, K.D. (eds) Zebrafish. Methods in Molecular Biology, vol 2707. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3401-1_22

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  • DOI: https://doi.org/10.1007/978-1-0716-3401-1_22

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3400-4

  • Online ISBN: 978-1-0716-3401-1

  • eBook Packages: Springer Protocols

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