Academia.edu no longer supports Internet Explorer.
To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to upgrade your browser.
2008, The Herptile
2007 •
2007 •
2008 •
Snakes of Medical importance in the Asian-Pacific Region
The Highly and Potentially Dangerous Elapids of Papua New Guinea1990 •
Journal of proteomics
Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka2014 •
The venom arsenal of the New Guinea small-eyed snake, Micropechis ikaheka, was investigated by a joint cDNA sequencing and venomics approach. Twenty-seven full-length DNA sequences encoding novel venom proteins were recovered in this study. Using this cDNA dataset we achieved locus-specific resolution for 19 out of the approximately 50 reverse-phase- and SDS-PAGE-separated venom proteins. The venom proteome of M. ikaheka is dominated by at least 29 D49-phospholipase A₂ (PLA₂) and 14 short and long neurotoxins of the three-finger toxin (3FTx) family. These protein classes represent, respectively, 80% and 9.2% of the total venom proteins. Two PIII-metalloproteinase (SVMP) molecules (7.6%), three CRISP isoforms (1.8%), and a single Kunitz-type inhibitor, vespryn, 5'-nucleotidase, serine proteinase and LAO molecules, none of which represents more than 0.7% of the total venom proteome, complete the protein arsenal of M. ikaheka. In concordance with clinical observations, this venom c...
Quarterly Journal of Medicine
The emerging syndrome of envenoming by the New Guinea small-eyed snake Micropechis ikaheka1996 •
Summary: The New Guinea small-eyed or Ikaheka snake, Micropechis ikaheka, which occurs throughout New Guinea and some adjacent islands, is feared by the indigenes. The first proven human fatality was in the 1950s and this species has since been implicated in many other cases of severe and fatal envenoming. Reliable attribution of envenoming to this species in victims unable to capture or kill the snake recently became possible by the use of enzyme immunoassay. Eleven cases of proven envenoming by M. ikaheka, with two fatalities, were identified in Papua New Guinea and Irian Jaya. Five patients showed no clinical signs of envenoming. The other six patients showed symptoms typical of envenoming by other Australasian elapids: mild local swelling, local lymphadenopathy, neurotoxicity, generalized myalgia, spontaneous systemic bleeding, incoagulable blood and passage of dark urine (haemoglobinuria or myoglobinuria). Two patients developed hypotension and two died of respiratory paralysis 19 and 38 h after being bitten. In vitro studies indicate that the venom is rich in phospholipase Az, is indirectly haemolytic, anticoagulant and inhibits platelets, but is not procoagulant or fibrinolytic. It shows predominantly post-synaptic neurotoxic and myotoxic activity. Anecdotally, Commonwealth Serum Laboratories' (CSL) death adder antivenom has proved ineffective whereas CSL polyvalent antivenom may be beneficial. Anticholinesterase drugs might prove effective in improving neuromuscular transmission and should be tested in patients with neurotoxic envenoming.
2000 •
Pseudonaja textilis is a widespread and common snake in eastern parts of Australia, but its distribution in New Guinea is poorly understood, and the origin of the New Guinea populations and its timing have been the subject of much specula- tion. Phylogenetic analysis of mitochondrial DNA sequences from three New Guinea populations of P. textilis indicates that New Guinea was
2008 •
Abstract: Pseudonaja textilis is a widespread and common snake in eastern parts of Australia, but its distribution in New Guinea is poorly understood, and the origin of the New Guinea populations and its timing have been the subject of much speculation. Phylogenetic analysis of mitochondrial DNA sequences from three New Guinea populations of P. textilis indicates that New Guinea was colonised from two independent eastern and western migration routes most likely in the Pleistocene. One dispersal event from northern Queensland led to the populations in eastern New Guinea (Milne Bay, Oro and Central Provinces, Papua New Guinea), whereas another, from Arnhem Land to central southern New Guinea, led to the populations from the Merauke area, Indonesian Papua. The results are consistent with the effects of Pleistocene sea level changes on the physical geography of Australasia, and are thus suggestive of a natural rather than anthropogenic origin of the New Guinea populations. The taxonomic status of the New Guinean populations is discussed. A pdf of this paper can be obtained from my website following the link.
2018 •
Journal of proteomics
Preclinical efficacy of Australian antivenoms against the venom of the small-eyed snake, Micropechis ikaheka, from Papua New Guinea: an antivenomics and neutralization study2014 •
2016 •
Bulletin of the Museum of Comparative Zoology
A New Species of New Guinea Worm-eating Snake, Genus Toxicocalamus (Serpentes: Elapidae), from the Star Mountains of Western Province, Papua New Guinea, with a Revised Dichotomous Key to the Genus2015 •
2018 •
Reptiles: Proceedings of the 1986 U.K. Herpetological Societies Symposium on Captive Breeding
The Pythons of New Guinea1987 •
Molecular Phylogenetics …
Snakes across the Strait: trans-Torresian phylogeographic relationships in three genera of Australasian snakes (Serpentes: Elapidae: Acanthophis, Oxyuranus, and …2005 •
PLoS Neglected Tropical Diseases
Preclinical Evaluation of Caprylic Acid-Fractionated IgG Antivenom for the Treatment of Taipan (Oxyuranus scutellatus) Envenoming in Papua New Guinea2011 •
2011 •
2011 •
Herpetology Notes
Micropechis ikaheka (Elapidae) in Papua, Indonesia: A Study of Diet and Cannibalism2015 •
Molecular phylogenetics and evolution
Wüster, W., A.J. Dumbrell, C. Hay, C.E. Pook, D.J. Williams & B.G. Fry (2005) Snakes across the Strait: Trans-Torresian phylogeographic relationships in three genera of Australasian snakes (Serpentes: Elapidae: Acanthophis, Oxyuranus and Pseudechis). Molecular Phylogenetics and Evolution 34: 1-14.2005 •
Molecular Phylogenetics and Evolution
Snakes across the Strait: trans-Torresian phylogeographic relationships in three genera of Australasian snakes (Serpentes: Elapidae: Acanthophis, Oxyuranus, and Pseudechis)2005 •
2006 •
Asian Herpetological Research
Herpetological Diversity of Timor-Leste: Updates and a Review of Species Distributions2015 •
Journal of Herpetology
Revision of the Genus Leiopython Hubrecht 1879 (Serpentes: Pythonidae) with the Redescription of Taxa Recently Described by Hoser (2000) and the Description of New Species2008 •
HAYATI Journal of Biosciences
Skin Histology and Microtopography of Papuan White Snake (Micropechis ikaheka) in Relation to Their Zoogeographical Distribution2013 •
Toxicon : official journal of the International Society on Toxinology
Williams, D., W. Wüster & B.G. Fry (2006) The good, the bad and the ugly: Australian snake taxonomists and a history of the taxonomy of Australia’s venomous snakes. Toxicon 48: 919-9302006 •
Amphibian and Reptile Conservation
Rediscovery of the rare Star Mountains Worm-eating Snake, Toxicocalamus ernstmayri O'Shea et al., 2015 (Serpentes: Elapidae: Hydrophiinae) with the description of its coloration in life2018 •
Molecular phylogenetics and evolution
Phylogenetic Relationships of Terrestrial Australo-Papuan Elapid Snakes (Subfamily Hydrophiinae) Based on Cytochrome band 16S rRNA Sequences1998 •
2014 •
2016 •
Toxicon : official journal of the International Society on Toxinology
Wüster, W., P. Golay & D.A. Warrell (1998) Synopsis of recent developments in venomous snake systematics, No. 2. Toxicon, 36: 299-3071998 •
Emergency Medicine Australasia
So close and yet so far: Health care in our nearest neighbour2006 •
2003 •