CA2239694A1 - Indane dimer compounds and their pharmaceutical use - Google Patents

Indane dimer compounds and their pharmaceutical use

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Publication number
CA2239694A1
CA2239694A1 CA002239694A CA2239694A CA2239694A1 CA 2239694 A1 CA2239694 A1 CA 2239694A1 CA 002239694 A CA002239694 A CA 002239694A CA 2239694 A CA2239694 A CA 2239694A CA 2239694 A1 CA2239694 A1 CA 2239694A1
Authority
CA
Canada
Prior art keywords
pharmaceutical use
dimer compounds
activity
indane
indane dimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002239694A
Other languages
French (fr)
Other versions
CA2239694C (en
Inventor
John Walsh
Neil Frankish
Helen Sheridan
Ronan Farrell
William Byrne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Venantius Ltd
Original Assignee
Venantius Limited
John Walsh
Neil Frankish
Helen Sheridan
Ronan Farrell
William Byrne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Venantius Limited, John Walsh, Neil Frankish, Helen Sheridan, Ronan Farrell, William Byrne filed Critical Venantius Limited
Publication of CA2239694A1 publication Critical patent/CA2239694A1/en
Application granted granted Critical
Publication of CA2239694C publication Critical patent/CA2239694C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • C07C13/45—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings with a bicyclo ring system containing nine carbon atoms
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    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
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    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Abstract

Indame dimer compounds and their pharmaceutical use particularly to achieve smooth muscle relaxing activity and/or mast cell stabilising activity and/or anti-inflammatory activity are described.
CA002239694A 1995-12-06 1996-12-06 Indane dimer compounds and their pharmaceutical use Expired - Lifetime CA2239694C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IE950922 1995-12-06
IE950922 1995-12-06
IE960762 1996-10-31
IE960762 1996-10-31
PCT/IE1996/000080 WO1997020802A1 (en) 1995-12-06 1996-12-06 Indane dimer compounds and their pharmaceutical use

Publications (2)

Publication Number Publication Date
CA2239694A1 true CA2239694A1 (en) 1997-06-12
CA2239694C CA2239694C (en) 2008-05-06

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CA002239853A Expired - Fee Related CA2239853C (en) 1995-12-06 1996-12-06 Indane dimer compounds and their pharmaceutical use
CA002239694A Expired - Lifetime CA2239694C (en) 1995-12-06 1996-12-06 Indane dimer compounds and their pharmaceutical use

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CA002239853A Expired - Fee Related CA2239853C (en) 1995-12-06 1996-12-06 Indane dimer compounds and their pharmaceutical use

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US (3) US6300376B1 (en)
EP (3) EP0873301B1 (en)
JP (3) JP2000506497A (en)
KR (2) KR19990072007A (en)
AT (3) ATE260241T1 (en)
AU (3) AU1169397A (en)
CA (2) CA2239853C (en)
DE (3) DE69631688T2 (en)
DK (1) DK0865419T3 (en)
GB (3) GB2322858A (en)
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