CA2562329A1 - Therapeutic antimicrobial compositions and methods - Google Patents

Therapeutic antimicrobial compositions and methods Download PDF

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Publication number
CA2562329A1
CA2562329A1 CA002562329A CA2562329A CA2562329A1 CA 2562329 A1 CA2562329 A1 CA 2562329A1 CA 002562329 A CA002562329 A CA 002562329A CA 2562329 A CA2562329 A CA 2562329A CA 2562329 A1 CA2562329 A1 CA 2562329A1
Authority
CA
Canada
Prior art keywords
acid
chain length
alkyl chain
branched alkyl
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002562329A
Other languages
French (fr)
Other versions
CA2562329C (en
Inventor
Michael Lynch
Rudyard Istvan
Bart Chernow
Manzer Durrani
Robert Ya-Lin Pan
Abel Saud
Rosa Laura Moese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
GMP|ANTI-INFECTIVE SOLUTIONS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GMP|ANTI-INFECTIVE SOLUTIONS Inc filed Critical GMP|ANTI-INFECTIVE SOLUTIONS Inc
Priority to CA002686815A priority Critical patent/CA2686815A1/en
Publication of CA2562329A1 publication Critical patent/CA2562329A1/en
Application granted granted Critical
Publication of CA2562329C publication Critical patent/CA2562329C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Abstract

Therapeutic antimicrobial compositions and methods for providing enhanced immediate and residual anti-viral and antibacterial efficacy against rhinovirus, rotavirus, coronovirus, respiratory syricytial virus, Gram-positive bacteria, Gram-negative bacteria and combinations thereof. More specifically, therapeutic antimicrobial compositions comprising an organic acid or organic acid mixture and a short-chain anionic surfactant having at least one of a large head group; a branched alkyl chain and an unsaturated alkyl chain, and therapeutic methods of use thereof.

Claims (13)

1. A method of treating or preventing a microbial caused infection in a patient in need thereof, said method characterized by comprising the step of administering an effective amount of antimicrobial composition comprising: a. from 0.2% to 70% of an organic acid; and b. from 0.1% to 40% of an anionic surfactant mixture having (i) a linear alkyl chain length of from C4 to C12 and a total head group size of at least 4 Angstroms; and/or (ii) a branched alkyl chain length of from C4 to C12; and/or (iii) a branched alkyl chain length of from C4 to C12 and a total head group size of at least 4 Angstroms;
wherein said composition is characterized by a pH of from 2.0 to 4.5.
2. The method of claim 1, wherein said anionic surfactant is characterized by being selected from the group consisting of: alkyl glyceryl sulfonate, alpha sulfo fatty acid, alkyl phosphonate, branched alkyl sulfonate and branched alkyl benzene sulfonate, secondary alkyl sulfate, mono ester of alkyl sulfosuccinic acid, alkyl isethionate, alkyl amidosulfonate, and combinations thereof.
3. The method according to any of the preceding claims, further wherein said anionic surfactant is characterized by being substituted with a sulfonate, sulfate or phosphonate group.
4. The method according to any of the preceding claims, wherein said organic acid is characterized by being selected from the group consisting of pyroglutamic acid, adipic acid, gluconic acid, gluconolactone acid, glutamic acid, glutaric acid, glycolic acid, tartaric acid, ascorbic acid and combinations thereof.
5. The method according to any of the preceding claims, wherein the antimicrobial composition is characterized by comprising a nonionic agent.
6. The method according to any of the preceding claims, wherein said nonionic agent is characterized by being selected from the group consisting of 1-(2-ethylhexyl) glycerol ether, octyl glycerol ether, 2-(2-ethylhexylxoxy) propanol, octyloxy-propanol, 1-(2-ethylhexyloxy) ethanol, octyloxy ethanol, 1,2-hexylenediol, 1,2-cyclohexanedimethanol, isopropyl glycerol ether and combinations thereof.
7. The composition according to any of the preceding claims, wherein said nonionic agent is characterized by being present in an amount of 0.1% to 10% by weight of total composition.
8. The method according to any of the preceding claims, wherein the microbial infection is characterized by being caused by at least one of the following: yeast, molds, bacteria or viruses.
9. The method according to any of the preceding claims where in the yeast is characterized by being from a Candida strain.
10. The method according to any of the preceding claims, wherein the bacteria is characterized by being either a gram negative or a gram positive
11. A method of disinfecting devices characterized by comprising treating a device with an effective amount of an antimicrobial composition comprising: a. from 0.2%
to 70% of an organic acid; and b. from 0.1 % to 40% of an anionic surfactant mixture having i. a linear alkyl chain length of from C4 to C12 and a total head group size of at least 4 Angstroms; and/or ii. a branched alkyl chain length of from C4 to C12; and/or iii, a branched alkyl chain length of from C4 to C12 and a total head group size of at least 4 Angstroms; wherein said composition is characterized by a pH of from 2.0 to 4.5.
12 The method of claim 11 wherein the antimicrobial composition is characterized by being applied as a wash, spray, soak, or a wipe.
13. A method of preventing infections originating in medical devices in a patient in need thereof characterized by comprising disinfecting the devices with an effective amount of an antimicrobial composition comprising: a. from 0.2% to 70% of an organic acid; and b.
from 0.1% to 40% of an anionic surfactant mixture having i. a linear alkyl chain length of from C4 to C12 and a total head group size of at least 4 Angstroms; and/or ii.
a branched alkyl chain length of from C4 to C12; and/or iii. a branched alkyl chain length of from C4 to C12 and a total head group size of at least 4 Angstroms; wherein said composition is characterized by a pH of from 2.0 to 4.5.
CA002562329A 2004-04-26 2005-04-26 Therapeutic antimicrobial compositions and methods Active CA2562329C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002686815A CA2686815A1 (en) 2004-04-26 2005-04-26 Therapeutic antimicrobial compositions and methods

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56531104P 2004-04-26 2004-04-26
US60/565,311 2004-04-26
PCT/US2005/014279 WO2005105070A2 (en) 2004-04-26 2005-04-26 Therapeutic antimicrobial compositions and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002686815A Division CA2686815A1 (en) 2004-04-26 2005-04-26 Therapeutic antimicrobial compositions and methods

Publications (2)

Publication Number Publication Date
CA2562329A1 true CA2562329A1 (en) 2005-11-10
CA2562329C CA2562329C (en) 2009-12-22

Family

ID=35149038

Family Applications (2)

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CA002686815A Abandoned CA2686815A1 (en) 2004-04-26 2005-04-26 Therapeutic antimicrobial compositions and methods
CA002562329A Active CA2562329C (en) 2004-04-26 2005-04-26 Therapeutic antimicrobial compositions and methods

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002686815A Abandoned CA2686815A1 (en) 2004-04-26 2005-04-26 Therapeutic antimicrobial compositions and methods

Country Status (15)

Country Link
US (1) US20050271711A1 (en)
EP (2) EP2298351A3 (en)
JP (1) JP2007534701A (en)
CN (1) CN1946428A (en)
AR (1) AR052399A1 (en)
AT (1) ATE492272T1 (en)
AU (1) AU2005237546B2 (en)
BR (1) BRPI0510327A (en)
CA (2) CA2686815A1 (en)
DE (1) DE602005025466D1 (en)
ES (1) ES2360803T3 (en)
IL (1) IL178894A0 (en)
MX (1) MXPA06012442A (en)
NO (1) NO20065457L (en)
WO (1) WO2005105070A2 (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050260243A1 (en) * 2004-04-26 2005-11-24 The Procter & Gamble Company Method of treating microbial plant diseases
CA2588782A1 (en) * 2004-12-09 2006-06-15 The Dial Corporation Compositions having a high antiviral and antibacterial efficacy
US20090012174A1 (en) * 2004-12-09 2009-01-08 The Dial Corporation Compositions Having a High Antiviral and Antibacterial Efficacy
CA2588802A1 (en) * 2004-12-09 2006-06-15 The Dial Corporation Compositions having a high antiviral and antibacterial efficacy
EP1830638A2 (en) * 2004-12-09 2007-09-12 The Dial Corporation Compositions having a high antiviral and antibacterial efficacy
US9629361B2 (en) 2006-02-09 2017-04-25 Gojo Industries, Inc. Composition and method for pre-surgical skin disinfection
US8119115B2 (en) 2006-02-09 2012-02-21 Gojo Industries, Inc. Antiviral method
US20070275929A1 (en) * 2006-05-24 2007-11-29 The Dial Corporation Composition and method for controlling the transmission of noroviruses
EP2040544A2 (en) * 2006-05-26 2009-04-01 The Dial Corporation Method of inhibiting the transmission of viruses
WO2007142919A2 (en) * 2006-05-30 2007-12-13 The Dial Corporation Compositions having a high antiviral effeicacy
US20070281999A1 (en) * 2006-05-31 2007-12-06 The Dial Corporation Alcohol-containing antimicrobial compositions having improved efficacy
EP2034826A2 (en) 2006-06-02 2009-03-18 The Dial Corporation Method of inhibiting the transmission of influenza virus
RU2008152442A (en) * 2006-06-05 2010-07-20 Дзей Дайл Корпорейшн (Us) METHODS AND PRODUCTS HAVING HIGH ANTIVIRAL AND ANTI-BACTERIAL EFFICIENCY
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
JP2010505964A (en) * 2006-10-10 2010-02-25 リンチ マイケル How to inactivate viruses
CN101662935A (en) * 2007-05-04 2010-03-03 宝洁公司 Antimicrobial compositions, products, and methods of use
US20090062391A1 (en) * 2007-08-27 2009-03-05 Kent Christopher New Use of a virucidal ointment in the nares for prevention of transmission and contraction of common colds
US20090136430A1 (en) * 2007-11-27 2009-05-28 Dugger Harry A Antihistamine/Corticosteroid preparations for the treatment of atopic dermatitis
GB0800788D0 (en) * 2008-01-16 2008-02-27 Glaxo Group Ltd Niovel formulation
JP5126745B2 (en) * 2008-07-22 2013-01-23 国立大学法人鳥取大学 Antiviral agent and antiviral sheet
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
US8106111B2 (en) 2009-05-15 2012-01-31 Eastman Chemical Company Antimicrobial effect of cycloaliphatic diol antimicrobial agents in coating compositions
US9744125B2 (en) * 2010-01-15 2017-08-29 Nuance Health, Llc Use of a virucidal preparation on an area of the face for prevention of transmission or contraction of viral illnesses, or to shorten the duration of, or lessen the severity of viral illnesses
CN103037934A (en) 2010-03-15 2013-04-10 安特提米派尼克有限公司 Device and method for delivering medicine into the tympanic cavity, with sliding assist
CA2841832C (en) 2011-07-12 2019-06-04 Pursuit Vascular, Inc. Device for delivery of antimicrobial agent into a trans-dermal catheter
US8841640B1 (en) 2013-03-13 2014-09-23 Inceptus Technologies, Llc Apparatus for infection control
FR3019714B1 (en) * 2014-04-10 2017-07-07 Salveco NEW BIOCIDAL PRODUCTS
EP3294404A4 (en) 2015-05-08 2018-11-14 ICU Medical, Inc. Medical connectors configured to receive emitters of therapeutic agents
FR3045382B1 (en) * 2015-12-17 2020-02-07 Tereos Starch & Sweeteners Belgium ANTIBACTERIAL COMPOSITION CONTAINING A MONOETHER OR A MONOACETAL OF DEOXYHEXOSE ALKYL
WO2018071717A1 (en) 2016-10-14 2018-04-19 Icu Medical, Inc. Sanitizing caps for medical connectors
JP6951421B2 (en) 2017-03-28 2021-10-20 ロンザ・ソリューションズ・アー・ゲー Water-soluble antibacterial composition
WO2018204206A2 (en) * 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
SG11202002632VA (en) 2017-09-26 2020-04-29 Ecolab Usa Inc Acidic/anionic antimicrobial and virucidal compositions and uses thereof
KR101968028B1 (en) 2017-12-26 2019-04-10 롯데첨단소재(주) Thermoplastic resin composition and article produced therefrom
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
EP3883638A1 (en) 2018-11-21 2021-09-29 ICU Medical, Inc. Antimicrobial device comprising a cap with ring and insert
CN111467338B (en) * 2020-04-07 2021-04-23 中国科学院深圳先进技术研究院 Application of pyroglutamic acid in preparation of medicine for preventing and treating novel coronavirus resistant to new coronary pneumonia
EP4255552A1 (en) 2020-12-07 2023-10-11 ICU Medical, Inc. Peritoneal dialysis caps, systems and methods

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1407997A (en) * 1972-08-01 1975-10-01 Procter & Gamble Controlled sudsing detergent compositions
US4136045A (en) * 1976-10-12 1979-01-23 The Procter & Gamble Company Detergent compositions containing ethoxylated nonionic surfactants and silicone containing suds suppressing agents
US4828912A (en) * 1981-07-20 1989-05-09 Kimberly-Clark Corporation Virucidal product having virucidal and/or germicidal properties
DE3229097A1 (en) * 1982-08-04 1984-02-09 Schülke & Mayr GmbH, 2000 Hamburg Microbicidal agents
US5006529A (en) * 1988-05-27 1991-04-09 Lever Brothers Company Soap compositions of enhanced antimicrobial effectiveness
DE4140473C2 (en) * 1991-12-09 1995-12-21 Schuelke & Mayr Gmbh Skin antiseptic and hand sanitizer
AU671208B2 (en) * 1993-06-30 1996-08-15 Colgate-Palmolive Company, The Anti-bacterial cleansing composition
US5681802A (en) * 1994-06-01 1997-10-28 Lever Brothers Company, Division Of Conopco, Inc. Mild antimicrobial liquid cleansing formulations comprising buffering compound or compounds as potentiator of antimicrobial effectiveness
US5653970A (en) * 1994-12-08 1997-08-05 Lever Brothers Company, Division Of Conopco, Inc. Personal product compositions comprising heteroatom containing alkyl aldonamide compounds
US6110445A (en) * 1995-06-26 2000-08-29 Colgate-Palmotive Company Oral composition exhibiting improved uptake and retention of antibacterial compounds on dental tissue surfaces
GB2309706B (en) * 1996-01-31 2000-02-09 Reckitt & Colman Inc Liquid detergent composition comprising quaternary ammonium surfactant having germicidal properties
US6190674B1 (en) * 1997-06-04 2001-02-20 Procter & Gamble Company Liquid antimicrobial cleansing compositions
US6190675B1 (en) * 1997-06-04 2001-02-20 Procter & Gamble Company Mild, rinse-off antimicrobial liquid cleansing compositions which provide improved residual benefit versus gram positive bacteria
US6488943B1 (en) * 1999-04-13 2002-12-03 The Procter & Gamble Company Antimicrobial wipes which provide improved immediate germ reduction
TR200201048T2 (en) * 1999-10-19 2002-08-21 The Procter & Gamble Company Compositions for the prevention and treatment of cold and flu-like symptoms
AU2001234509A1 (en) * 2000-01-20 2001-07-31 The Procter And Gamble Company Antimicrobial compositions
DE60124906T2 (en) * 2000-06-05 2007-05-24 S.C. Johnson & Son, Inc., Racine BIOZIDE CLEANING AGENTS
US20020192407A1 (en) * 2001-03-01 2002-12-19 The Procter & Gamble Company Pre-moistened wipe with improved feel and softness
FR2822377A1 (en) * 2001-03-23 2002-09-27 Oreal USE OF FIBERS AS ANTI-IRRITANT AGENT IN A COSMETIC OR DERMATOLOGICAL COMPOSITION
US6846846B2 (en) * 2001-10-23 2005-01-25 The Trustees Of Columbia University In The City Of New York Gentle-acting skin disinfectants
US7067227B2 (en) 2002-05-23 2006-06-27 Applied Materials, Inc. Sensitized chemically amplified photoresist for use in photomask fabrication and semiconductor processing
NZ536482A (en) 2002-06-21 2007-03-30 Procter & Gamble Antimicrobial compositions, hygiene and personal care products and use thereof
US20040001797A1 (en) * 2002-06-21 2004-01-01 Abel Saud Antimicrobial compositions, products and methods employing same
US20050260243A1 (en) * 2004-04-26 2005-11-24 The Procter & Gamble Company Method of treating microbial plant diseases

Also Published As

Publication number Publication date
AU2005237546A1 (en) 2005-11-10
EP2298351A2 (en) 2011-03-23
EP1740166B1 (en) 2010-12-22
AR052399A1 (en) 2007-03-21
IL178894A0 (en) 2007-03-08
MXPA06012442A (en) 2007-01-17
BRPI0510327A (en) 2007-10-23
CN1946428A (en) 2007-04-11
JP2007534701A (en) 2007-11-29
EP1740166A2 (en) 2007-01-10
CA2686815A1 (en) 2005-11-10
US20050271711A1 (en) 2005-12-08
NO20065457L (en) 2006-11-27
ATE492272T1 (en) 2011-01-15
ES2360803T3 (en) 2011-06-09
WO2005105070A3 (en) 2006-03-16
AU2005237546B2 (en) 2009-09-10
DE602005025466D1 (en) 2011-02-03
CA2562329C (en) 2009-12-22
EP2298351A3 (en) 2012-06-06
WO2005105070A2 (en) 2005-11-10

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