CN102872200A

CN102872200A - Externally-applied medicine for treating alopecia areata

Info

Publication number: CN102872200A
Application number: CN2011101935614A
Authority: CN
Inventors: 郑绯丹
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-07-12
Filing date: 2011-07-12
Publication date: 2013-01-16

Abstract

The invention discloses an externally-applied medicine for treating alopecia areata, comprising 8 kinds of ingredients consisting of dalbergia odorifera, polygonum multiflorum, herba ecliptae, fructus psoraleae, salviae miltiorrhizae, cortex mori radicis, borneol and 95% alcohol. The medicine disclosed herein has significant effect of treating alopecia areata and alopecia with the advantages of reliable curative effect, rapid effect, convenient usage, and no toxic and side effect. Clinical application for many years prove that the effective rate is more than 98%, the cure rate is 97%, and the medicine is an optimum traditional Chinese medicine preparation for treating alopecia areata and alopecia at present.

Description

A kind of medicine for external use for the treatment of alopecia areata

Technical field: the present invention is a kind of medicine for external use for the treatment of alopecia areata, belongs to the technical field of traditional Chinese medicine and preparation method.

Background technology: the traditional Chinese medical science is thought the common green grass or young crops of primary disease, postadolescent, and by containing in the heat in blood, multiple irritated by mind, seven emotions are unsuccessful, and strongly fragrant fire-transformation of a specified duration accumulates in burning hot, intense heat bringing about wind syndrome, " pneumatic leaf falls ", hair is alopecia therefore.So teenager is suffered from primary disease, mostly is due to the interior-heat, its treatment also should be with clearing away heat and cooling blood, the agent of the hair growth promoting of dispeling the wind.Can't absurdly take tonic.Otherwise more benefit is hotter, and more Re Zefa more falls.The spirit emotion changes is one of major reason of primary disease, and Chinese and western medicine is consistent on this aspect.As long as keep in daily life stable, the sufficient sleep of emotion, just can prevent the alopecia that causes because of direct stimulation, overfatigue as far as possible.Alopecia areata (Alopecia areata) is commonly called as " alopecia areata ", is a kind of patchy alopecia trichopathy of limitation that suddenly occurs.It has three kinds of alopecia areatas, alopecia totalis, alopecia universalis.Its lesion scalp is normal, NIP and subjective symptoms.The primary disease course of disease is through slow, but spontaneous remission and recurrence.If whole hair of scalp all comes off, claim alopecia totalis (alopecia totalis); The person if all hairs of whole body all do not come off claims alopecia universalis (alopecia universalis).Primary disease and deficiency in both Qi and blood, deficiency of the liver and kindey, blood stasis hair key is relevant.Hair is the sign of blood condition, the deficiency of vital energy then blood are difficult living, and Rhizoma Imperatae must not need to support, therefore deal with in flakes; Blood stored in the liver, kidney storing essence, asthenia of essence and blood are then sent out the source without growth; Block bloody path, fresh blood can not hair care, therefore falling out.Dialectical being divided into: heart deficiency of spleen-QI (dream that mind is smooth, have a dizzy spell, sleep night many, have a sleepless night), stagnation of liver-QI blood stasis (that gas rushes down is uncomfortable in chest, hepatosplenomegaly, sternal rib pain), QI and blood deficiency (after being ill or sick for a long time alopecia, refreshing disease is weak, pale complexion, emaciated physique), deficiency of the liver and kindey (dizziness and tinnitus, lumbago and backache, seminal emission lingering diarrhea, the sexual impotence xerostomia).Their cause of disease and treat roughly the same, the degree difference of clinical manifestation just.The alopecia of head burst limitation speckle shape, circular or oval, differ in size, the border is obvious, and local hair purifies and NIP, no conscious sympton, Chang Yu stumbles on.Indivedual severe patients can be developed to alopecia totalis, and very person's eyebrow, armpit hair, pubes also can come off entirely.The sustainable several months of the course of disease is to the several years.What have shows as the alopecia of head limitation patch shape, and rounded, ellipse or map shape differ in size, sharpness of border, and the smooth NIP of alopecia place scalp, and hair is easily pulled out around it.Some patient hair within a couple of days or several months all comes off, and is referred to as alopecia totalis; Severe patient eyebrow, armpit hair, pubes, fine hair on birds or animals hair can doublely occur and come off, and is referred to as alopecia universalis.General alopecia district no conscious sympton, minority can occur that local scalp is little itches or feeling of numbness etc.In general, mostly recovery process is to have first tiny soft white hair growth to go out, and sometimes can take off with the personal attendant, and the chap blackening recovers normal gradually.Occur more suddenly, on the rear discovery head of sometimes getting up in the morning the circular alopecia spot that differs in size is arranged.The morbidity of alopecia areata is relevant with neural Nervous and Mental Factors.May be because spiritual high-pressure has affected neural regulative mechanism, directly or indirectly damage hair follicle, cause alopecia.Alopecia areata is circle, oval alopecia to occur suddenly as feature take hair.Any position at human body can be given birth to by first alopecia district, but is common in head.Be the general multiple scalp of being born in of alopecia areata, but also other positions can occur, locate such as eyebrow, beard etc.Primary disease Chang Yu stumbles on or is found by other people, no conscious sympton, and minority case at the initial stage of a disease affected part can have the mile abnormality sensation.Any position at human body can be given birth to by first alopecia district, but is apt to occur in head.Generally at scalp, or eyebrow, beard etc. are located.According to estimates, among the crowd sickness rate of alopecia areata less than 0.1%; Approximately there is 95% patients with alopecia areata pathological changes only to be confined to scalp.Alopecia areata often shows as the hair position and independently circumscribed alopecia in blocks occurs, and is circular or oval, edge clear, diameter 1～2cm or larger.Alopecia district skin smooth, shinny, without significantly atrophy, but still have pore as seen, hair difficult drop-off around the infringement, the hair root that comes off attenuates, ball top dwindles, can form the exclamation mark shape "! ".If infringement increases gradually, number increases, and adjacent skin lesion district can be fused into mutually and differ in size, patch in irregular shape.Often there are some pines in the edge in alopecia district and the hair that easily takes off, and what have fractures, the often atrophy of proximal hair.As this hair is extracted, can see this hair upper coarse and lower fine and the picture exclamation mark (! ), and the trichochromes of bottom also takes off mistake.This phenomenon is advanced sign.If the state of an illness continues development, skin lesion can involve full head, so that hair all comes off.At this moment, scalp still can keep normal appearance, is to be alopecia totalis.Serious case, except hair came off entirely, other hairs everywhere of whole body comprised eyebrow, eyelashes, beard, armpit hair, pubes and whole body chaeta etc., all can come off, this situation is called alopecia universalis.In male's patients with alopecia areata, approximately there is 10% people may develop into alopecia universalis.

Summary of the invention: the present invention has: Lignum Dalbergiae Odoriferae, Radix Polygoni Multiflori, Herba Ecliptae, Fructus Psoraleae, Radix Salviae Miltiorrhizae, Cortex Mori, Borneolum Syntheticum and 95% ethanol 8 flavor medicines form.

Specific implementation method: have in per 1000 milliliters of finished medicines: Lignum Dalbergiae Odoriferae 20 gram, Radix Polygoni Multiflori 30 grams, Herba Ecliptae 20 grams, Fructus Psoraleae 30 grams, Radix Salviae Miltiorrhizae 20 grams, Cortex Mori 30 grams, Borneolum Syntheticum 10 grams are 950 milliliters of totally 160 grams and 95% ethanol.

Production technology may further comprise the steps:

1, with crude drug by the prescription weight standard of weighing.

2, the crude drug that weighs up is put under the burning sun (or oven dry) dehydrate that is exposed to the sun.

3, the crude drug of dehydrate being pulverized with the high speed medicinal material pulverizer is the above medicated powder of 150 orders.

4, medicated powder being put into 95% ethanol soaked 72 hours.

5, medicated wine is centrifugal with centrifuge, precipitation, filter.

6, will filter in the plastic bottle that good medicated wine is filled to 2.5 milliliters, sealing, packing, for subsequent use.

Fang Zhongdan medicine pharmacology analysis: Lignum Dalbergiae Odoriferae blood circulation promoting and blood stasis dispelling, expansion blood improve local blood circulation, and the treatment speckle is bald; Radix Polygoni Multiflori invigorating the liver and kidney, benefiting essence-blood, black beard and hair; The sweet acid of Herba Ecliptae, cold clinically are usually used in treating early whitening of beard and hair; Fructus Psoraleae has warming the kidney to activate YANG, and improving inspiration by invigorating kidney-QI waits effect, is used for curing vitiligo, the cards such as alopecia areata outward; Radix Salviae Miltiorrhizae improves microcirculation, increases blood flow; Cortex Mori sweet in the mouth, cold enters spleen channel, and alopecia is had certain effect; The Borneolum Syntheticum awaking drug, external can increase skin penetration, and compatibe drug skin is absorbed, and plays therapeutical effect.Reasonable recipe of the present invention, compatibility is proper, scientific and precise, the treatment alopecia areata is evident in efficacy reliable.

Implement case 1, Zhang Jing, woman, 42 years old, cotton mill, Weifang nurse, the head alopecia areata was used multiple medicines such as " 101 " for many years, poor effect, rear medicine for external use of the present invention, the affected part of exterior coating 10 days accepted, the alopecia areata place sees that namely hair grows, and after 30 days, new long hair covers the alopecia areata place, slightly short except institute's growing new hair, scalp has loseed the alopecia areata point, follows up a case by regular visits to after 3 years, hair is dense, reaches the clinical cure purpose.

Implement case 2, He Tongfu, man 38, Linqu five well people, because causing the head alopecia areata, seborrheic dermatitis counts the place, Chinese medicine and western medicine has been used much, has little effect, and cures under patient's the introduction in here afterwards, accept medicine for external use treatment of the present invention, one week of affected part of exterior coating, namely see new growing, continue to smear at the acomia place of alopecia areata, after 30 days everywhere alopecia areata new growing all arranged, cover scalp.

Claims

1. medicine for external use for the treatment of alopecia areata, it is characterized in that this invention is as raw material take Chinese herbal medicine, its composition and formulation weight are as follows: Lignum Dalbergiae Odoriferae 20 gram, Radix Polygoni Multiflori 30 grams, Herba Ecliptae 20 grams, Fructus Psoraleae 30 grams, Radix Salviae Miltiorrhizae 20 grams, Cortex Mori 30 grams, Borneolum Syntheticum 10 grams, totally 160 grams and 95% ethanol are 950 milliliters.

2. production technology may further comprise the steps:

1) with crude drug by the prescription weight standard of weighing.

2) crude drug that weighs up is put under the burning sun (or oven dry) dehydrate that is exposed to the sun.

3) crude drug of dehydrate being pulverized with the high speed medicinal material pulverizer is the above medicated powder of 150 orders.

4) medicated powder being put into 95% ethanol soaked 72 hours.

5) medicated wine is centrifugal with centrifuge, precipitation, filter.

6) will filter in the plastic bottle that good medicated wine is filled to 2.5 milliliters, sealing, packing, for subsequent use.