DE69631688D1 - Indanverbindungen mit relaxierender wirkung auf die glatten muskeln und/oder mit mastzellen stabilisiernder und/oder entzuendungshemmender wirkung - Google Patents

Indanverbindungen mit relaxierender wirkung auf die glatten muskeln und/oder mit mastzellen stabilisiernder und/oder entzuendungshemmender wirkung

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Publication number
DE69631688D1
DE69631688D1 DE69631688T DE69631688T DE69631688D1 DE 69631688 D1 DE69631688 D1 DE 69631688D1 DE 69631688 T DE69631688 T DE 69631688T DE 69631688 T DE69631688 T DE 69631688T DE 69631688 D1 DE69631688 D1 DE 69631688D1
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bond
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DE69631688T2 (de
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John Walsh
Neil Frankish
Helen Sheridan
William Byrne
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Venantius Ltd
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Venantius Ltd
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    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
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    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
DE69631688T 1995-12-06 1996-12-06 Indanverbindungen mit relaxierender Wirkung auf die glatten Muskeln und/oder mit Mastzellen stabilisierender und/oder entzündungshemmender Wirkung Expired - Fee Related DE69631688T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IE950922 1995-12-06
IE950922 1995-12-06
IE960762 1996-10-31
IE960762 1996-10-31
PCT/IE1996/000082 WO1997020806A1 (en) 1995-12-06 1996-12-06 Indane compounds with smooth muscle relaxing and/or mast cell stabilising and/or anti-inflammatory activity

Publications (2)

Publication Number Publication Date
DE69631688D1 true DE69631688D1 (de) 2004-04-01
DE69631688T2 DE69631688T2 (de) 2005-01-20

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DE69629390T Expired - Fee Related DE69629390T2 (de) 1995-12-06 1996-12-06 Indandimerverbindungen mit relaxierender wirkung auf die glatten muskeln und/oder mit mastzellen stabilisiernder und/oder entzuendungshemmender wirkung
DE69629387T Expired - Lifetime DE69629387T2 (de) 1995-12-06 1996-12-06 Dimere indan verbindungen und ihre pharmazeutische verwendung
DE69631688T Expired - Fee Related DE69631688T2 (de) 1995-12-06 1996-12-06 Indanverbindungen mit relaxierender Wirkung auf die glatten Muskeln und/oder mit Mastzellen stabilisierender und/oder entzündungshemmender Wirkung

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DE69629390T Expired - Fee Related DE69629390T2 (de) 1995-12-06 1996-12-06 Indandimerverbindungen mit relaxierender wirkung auf die glatten muskeln und/oder mit mastzellen stabilisiernder und/oder entzuendungshemmender wirkung
DE69629387T Expired - Lifetime DE69629387T2 (de) 1995-12-06 1996-12-06 Dimere indan verbindungen und ihre pharmazeutische verwendung

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JP (3) JP2000502328A (de)
KR (2) KR19990071978A (de)
AT (3) ATE246670T1 (de)
AU (3) AU1169197A (de)
CA (2) CA2239853C (de)
DE (3) DE69629390T2 (de)
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GB (3) GB2322858A (de)
IE (1) IE960865A1 (de)
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AU8031698A (en) * 1997-06-05 1998-12-21 Venantius Limited Indane compounds and their pharmaceutical use
JP2001064202A (ja) * 1999-08-25 2001-03-13 Kissei Pharmaceut Co Ltd 心不全予防治療剤
DE10142660A1 (de) 2001-08-31 2003-03-20 Aventis Pharma Gmbh Verwendung von Derivaten von C2-substituierten Indan-1-ol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
DE10142663B4 (de) * 2001-08-31 2004-08-19 Aventis Pharma Deutschland Gmbh C2-Disubstituierte Indan-1-ol-Systeme
DE10142668A1 (de) * 2001-08-31 2003-03-20 Aventis Pharma Gmbh Verwendung von C2-substituierten Indan-1-on-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
DE10142661B4 (de) 2001-08-31 2004-06-09 Aventis Pharma Deutschland Gmbh Mehrfach substituierte Indan-1-ol-Systeme und ihre Verwendung als Arzneimittel
DE10142665B4 (de) 2001-08-31 2004-05-06 Aventis Pharma Deutschland Gmbh C2-Disubstituierte Indan-1-one und ihre Derivate
DE10142667B4 (de) 2001-08-31 2004-06-09 Aventis Pharma Deutschland Gmbh C2-substituierte Indan-1-ole und ihre Derivate und ihre Verwendung als Arzneimittel
DE10142662B4 (de) 2001-08-31 2004-07-08 Aventis Pharma Deutschland Gmbh Derivate von C2-substituierten Indan-1-ol-Systemen und ihre Verwendung als Arzneimittel
DE10142659A1 (de) * 2001-08-31 2003-03-20 Aventis Pharma Gmbh Verwendung von mehrfach substituierten Indan-1-ol. Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
DE10142666A1 (de) 2001-08-31 2003-03-20 Aventis Pharma Gmbh Verwendung von C2-substituierten Indan-1-ol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
DE10142722A1 (de) * 2001-08-31 2003-03-27 Aventis Pharma Gmbh C2-substituierte Indan-1-one und ihre Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US10517839B2 (en) * 2008-06-09 2019-12-31 Cornell University Mast cell inhibition in diseases of the retina and vitreous
US9260376B2 (en) 2011-07-22 2016-02-16 Venantius Limited Compounds for use in the treatment of immune related inflammatory disease
CA2839606A1 (en) 2011-07-22 2013-01-31 Venantius Limited Indene derivatives for use in the treatment of inflammatory bowel disease
EP2734497A1 (de) * 2011-07-22 2014-05-28 Venantius Limited Indandimere zur verwendung bei der behandlung von autoimmunentzündlichen krankheiten
US20150141506A1 (en) * 2012-05-24 2015-05-21 Venantius Limited Indane dimers for use in the treatment of autoimmune inflammatory disease
EP2864279B1 (de) 2012-05-24 2016-11-02 Venantius Limited Verbindungen zur verwendung bei der behandlung von entzündlichen autoimmunkrankheiten
CN113660932A (zh) * 2019-03-29 2021-11-16 景凯生物科技股份有限公司 具有侧链烷基与烯基延伸的苯基衍生物及包括有其的药学组合物
CN111533764B (zh) * 2020-05-12 2023-06-06 杭州师范大学 一种利用多米诺反应制备硅氧基茚衍生物的方法

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GB2322859A (en) 1998-09-09
GB9812216D0 (en) 1998-08-05
GB2322858A (en) 1998-09-09
EP0873301A1 (de) 1998-10-28
KR19990071978A (ko) 1999-09-27
ATE260241T1 (de) 2004-03-15
DE69629387T2 (de) 2004-06-24
IE960865A1 (en) 1997-06-06
CA2239694C (en) 2008-05-06
EP0865419B1 (de) 2003-08-06
CA2239853A1 (en) 1997-06-12
US6297399B1 (en) 2001-10-02
JP2000502328A (ja) 2000-02-29
CA2239853C (en) 2006-11-28
DE69631688T2 (de) 2005-01-20
AU1169197A (en) 1997-06-27
US6300376B1 (en) 2001-10-09
EP0874800B1 (de) 2003-08-06
AU1169297A (en) 1997-06-27
WO1997020805A1 (en) 1997-06-12
EP0874800A1 (de) 1998-11-04
IL124756A0 (en) 1999-01-26
IL124756A (en) 2006-04-10
ATE246668T1 (de) 2003-08-15
DE69629390D1 (de) 2003-09-11
WO1997020806A1 (en) 1997-06-12
CA2239694A1 (en) 1997-06-12
IL124795A0 (en) 1999-01-26
DE69629387D1 (de) 2003-09-11
GB9812213D0 (en) 1998-08-05
WO1997020802A1 (en) 1997-06-12
EP0865419A1 (de) 1998-09-23
DE69629390T2 (de) 2004-06-24
DK0865419T3 (da) 2003-11-10
GB2323088A (en) 1998-09-16
GB9812215D0 (en) 1998-08-05
KR19990072007A (ko) 1999-09-27
AU1169397A (en) 1997-06-27
JP2000506497A (ja) 2000-05-30
EP0873301B1 (de) 2004-02-25
JP2000502072A (ja) 2000-02-22
US6423752B1 (en) 2002-07-23
ATE246670T1 (de) 2003-08-15
AU724648B2 (en) 2000-09-28
IL124795A (en) 2001-01-28
US20020052530A1 (en) 2002-05-02

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