US2641259A - Electrophysiotherapy apparatus - Google Patents

Electrophysiotherapy apparatus Download PDF

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US2641259A
US2641259A US52845A US5284548A US2641259A US 2641259 A US2641259 A US 2641259A US 52845 A US52845 A US 52845A US 5284548 A US5284548 A US 5284548A US 2641259 A US2641259 A US 2641259A
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capacitor
nerve
transformer
meter
nerves
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US52845A
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Batrow John
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BARTOW LAB Inc
BARTOW LABORATORIES Inc
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BARTOW LAB Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/3603Control systems
    • A61N1/36034Control systems specified by the stimulation parameters

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  • This invention relates to electro-physiotherapy, and this application is a continuation-in-part of my application, Serial No. 577,296, filed February 10, 1945. This application discloses circuit improvements not disclosed in said application Serial No. 577,296, now abandoned.
  • It is still another object to provide an improved electro-therapy apparatus relatively steepwalled initial surges or pulses of current may be induced in a body so that relatively deep penetration of the electrical impulses may take place.
  • Fig. 1 is a schematic diagram of an electrophysiotherapy apparatus embodying principles of the invention
  • Fig. 1a graphically illustrates the time variation of voltage, characteristic of a wave train produced by the apparatus of Fig. 1;
  • FIG. 2 schematically shows alternative apparatus incorporating features of the invention.
  • My improved equipment is designed to excite, stimulate or modulate upon the nervous system of the body. While the complete physical process of such stimulation and modulation has not yet been established to the satisfaction of all, it is possible that the process in accordance with which my improved equipment is believed to affect the body may be based upon one or more of the following premises:
  • That cellular membrane behaves like manmade electric condensers, and that the membrane capacitance is very high.
  • That chemical status of cells or organs is determined by the hydrogen-ion concentration.
  • That the autonomic nervous system is the regulating mechanism which maintains ionic balance of cells, or hydrogen-ion concentration.
  • the autonomic nervous system consists of two major branches-sympathetic and parasympathetic; the sympathetic system positively changes the organs (catabolic action), and the parasympathetic system negatively charges the organs (anabolic action).
  • both branches of the autonomic nervous system are antagonistic to one another in action; the frequency of charge or discharge of the cells, tissues, and organs must be at a rate so as to overcome the antagonistic action of the nerve-causing disturbance.
  • That the current flow and the current density at the skin must be of relatively low amplitude to avoid burns, shocks, or other unpleasant sensations.
  • My improved equipment therefore includes improved means essentially for the purpose of eifecting the charging negatively or the charging positively, as may be required, of cellular membranes of the human body, which cellular membranes, as indicated above, behave after the manner of man-made condensers.
  • My improved equipment is constructed and arranged to bias the membrane condensers as to polarity and to return them to that state required for normal health or at least to attempt the alleviation of a given pathological condition.
  • Novel indicating means may be employed to assist in making the necessary determinations.
  • Fig. 1 of the-drawings my invention is shown in application to a mechanically interrupted system for applying pulse excita tions to the body between a pair of electrodes 56.
  • One of the electrodes"5''6 may be a gas-filled discharge device having an envelope of non-conducting material and for direct application to the body.
  • the electrode or applicator 5 is such a gas-filled discharge device and is shown to comprise a relatively extensive Winding of non-conducting tubing, such as glass tubing, communicating with a handle portion 1.
  • a single electrode 8 may be supported within the handle portion 1, and the entire device may be 'filled with an ionizable inert gas, such as neon, under relatively low pressure.
  • the other body-contact electrode may be a metal plate, either for directcontact as by clamping to a'given part of the body, or for use as a platform on which-the patient may stand.
  • the means for stimulating a body by the electrodes 5 6- may include a capacitor 9 that is suitably charged.
  • the equipment' is designed to operate from a source of alternating current; the charging means for capacitor 9 may therefore include full-wave rectifier means with suitable smoothing elements ll, I2, and 13 to apply a smoothed direct-current potential across a load resistor l4.
  • Potentiometer means 15-46 may be employed for adjusting the magnitude of direct-current utilized to charge the capacitor 9, and in order toprovide' forthe selective reversal of polarity of this charge, there may be a reversing switch I! between the resistor l4 and the capacitor 9.
  • the capacitor 9 is intermittently discharge through suitable diiferentiating means for application of pulses (characterized by relatively sharp upswings or leading edges) across the bodycontact electrodes -6.
  • means may be a step-up transformer, such as the autotransformerv l8, and the capacitor 9 may be directly connected to the primary of the autotransformer l8 through a mechanical contactor or interrupter IS.
  • the contactor [9 may include a pair of opposed conductive segments (connected to each other) to be contacted periodically by a-continually rotating contact finger 2
  • the contactor I9 may include, two further opposed conductive segments-23,- which are also connected to each-other and which may be selectively utilized instead of the segments 20, depending upon the selected positioning of a switch 24.
  • the discharge. of capacitor 9 may be accompanied by such surges as to draw arcs between finger 2
  • the life of a contactor such as the contactor 19 may then be extended by-shifting the switch 24 so as to employ segments 23 (inplace of The differentiating segments 20) for the discharge of capacitor 9.
  • the single electrode 8 of the gas-discharge device 5 may be connected to one side of the secondary of transformer I8, and the secondary circuit may be completed through the body to ground, as through a number of selectively insertable resistances 25-2 6--2I between the electrode 6 and ground.
  • the resistances 25262'l form .part of what I term a meter or indicator circuit to be employed for quantitive diagnostic and pathological purposes.
  • This meter circuit is shown to include a current-responsive device 28. which may be merely an ammeter bridging the resistance 2'!, and the effective resistance of the element 2'! may be reduced as desired by selectively inserting further shunt resistances 29-30, as by operation of switches 3l32.
  • the meter circuit is completed by a further branch including a spark gap 33 and a resistor 34, bridging the rest of the described meter circuit between the electrode 6 and ground.
  • the patient may stand upon the electrode 6 with preferably bare or with stocking feet, and the manually unanipulable electrode or applicator 5 may be applied to certain parts of the body, depending upon the organ to be treated or examined, as will laterfbe clear.
  • the capacitor 9 is normally charged and, as soon as the contact finger 2
  • the transformer [8 will be understood to provide not only a vastly increased step-up in mag nitude of voltage, as compared with the voltage discharged from capacitor'9, but also in effect to differentiate the wave form of the'discharge from capacitor 9.
  • the differentiated output appearingin the secondary of the transformer 18 may be characterized by relatively highvoltage surge that may attain its maximum amplitude in a relatively short time.
  • thisfirst surge is merely the beginning of a highly damped oscillatory wave train (see Fig. la) that is repeatedly produced once for every discharge of the capacitor 9.
  • The, meter circuit may provide the principal component of the high resistance responsible for fast damping, thereby rapidly making available a relatively long quiescent period, in order to permit a certain amount of nerve recovery before application of the next succeeding stimulation impulse.
  • the relatively rapid initial polarized voltage surge'in the output of the transformer may be able to cause electrical penetration within the body where a more slowly rising wavewould otherwise be blocked by polarization effects in the nerves.
  • the rapid rise of current transmitted to the body may also be made possible by the non-linear impedance properties of the gas-discharge applicator 5.
  • the conducting gas and the fluids within the body become, in effect, opposite plates of a capacitative coupling element in the secondary circuit (which in,- cludes the body); the glass of electrode 5 and the skin of the body constitute the dielectric of the capacitative coupling.
  • the capacitance of this coupling may present a relatively low impedance to the very high frequency components of the initial surge of the stimulating wave train.
  • Fig. 2 I show a modified form of the invention in which completelyelectric means are employed not only for the generation of stimulating impulses but also for periodically discharging a capacitor 46.
  • the means for charging the capacitor 40 may employ half-wave rectifier means 4
  • the relay 44 may be energized by an indirectly-heated full-wave rectifier 45, as when emission becomes estabilshed in rectifier 45; and, of course, the solenoid of relay 44 will thereafter remain energized as long as the required voltage is applied to the system.
  • I employ a gasdischarge device, such as a thyratron 46, periodically to apply to capacitor 40 the charging voltage from the circuit of rectifier 4
  • a gasdischarge device such as a thyratron 46
  • the cathode of thyratron 46 will be at the high anode potential, so that the full voltage output of rectifier 4
  • Due to the high capacitance of capacitor 4
  • the secondary of the transformer 41 may include a connection to a manually manipulable gas-filled applicator 48, which may be generally similar toithe applicator 5 described in connection with Fig. 1.
  • reversing-switch means 49 may serve to reverse polarity of the capacitor discharge as it is applied to the primary of transformer 41, thus providing a means for control of the direction of the initial surges of the wave trains generated in the secondary circuit of transformer 41.
  • may be included in the secondary circuit of the transformer 41.
  • a meter circuit as described in connection with Fig. 1 such a meter circuit may employ a body-contact electrode 52 connected to ground, on the one hand, through a resistor 53 and spark gap 54 and, on the other hand, through a meter 55 associated with a plurality of adjustably selectable resistances.
  • Operation of the switching means 46 for pcriodically discharging the capacitor 40 may employ any desired technique that provides periodic control or firing impulses for the grid circuit of the thyratron 46, as via the coupling transformer 56.
  • I assume a source of alternating current having a frequency of n cycles per second, and I employ a cascaded frequency divider of 0: stages, such that n/zc may provide the desired repetition rate of discharging capacitor 40. It will be recalled that this desired rate is of the order of '10 to 20 per second; for the 60 cycle case, therefore, a five-stage frequency divider may provide a desired excitation rate of 12 per second.
  • the frequency divider of Fig. 2 may operate from a full-wave rectifier 5 8, which may provide through its cathode circuit a suitable B supply for a pulse-generating tube 66, and which through one of its anode circuits may provide bias control for the grid of tube 60.
  • a single short triggering impulse i. e. one for every full cycle of the supply voltage
  • the tube 60 will thus be rendered conductive once every cycle of the supply voltage.
  • a control impulse or surge derived from a potentiometer 6
  • each of the tubes 62 to 66 may be in its particular cathode circuit and, from left to right in the sense of drawing, each oathode load resistor of each tube is coupled to the grid of the next-succeeding tube stage.
  • Each of the cathode circuits of the switching tubes 62-66 may be bridged by a capacitor, such as the capacitor 61 across the load resistor 66 in the circuit of tube 62, so that upon conduction of a switching tube, such as the tube 62, the voltage appearing across its load resistor (68) may charge its load capacitor (61).
  • the charge on capacitor 61 may be held sufiiciently long to maintain a reduced bias on the control grid of the next-succeeding tube stage 63, so that upon generation of the next pulse (corresponding to the next cycle of the supply voltage), as derived from potentiometer 6
  • the voltage appearing across .theloadxresistor 89 is available Ito 'charge: capacitor 10' for appropriate reduction of the. bias on the control grid of theinext succeeding stage 64; and, of course, the next succeeding. impulse maybe: effective to operate the tube GLtothe. exclusionof the other switching tubesfl til, and, 66.
  • the switching or tubetrlggeringsequence maybe rendered self-recycling by coupling the cathode-circuit output" of tube 66 back to the control grid of the first switching stag-e62,- as will be clear. It will thus be seen that-for every timing impulse supplied a) the thyratron 46-, there will have been five successive operations ofthe various stages of the frequency divider and that these stages will have beenoperatedby five successive cycles of the supply voltage. For a GO-cycle supply, the thyratron 46 will-thusbe'fired at a repetition rate ofl2' per second.
  • the rise time of the principal pulse output shall be of the order of 50- microseconds, with a rise to'75 percent of the peak of this pulse in an interval of the order of 20 n icroseconds; It is known that the preferred repetition rate of 12 per second (or at least between 10 and 20" per secondlis below the normal impulse rateof nerve action; for these rates, a preferred duty cycle of; the order of 10" i's-tlius indicated.
  • duty cycle is meant the fraction al relation between the time duration of the principal outpu't'- pulse and the time'interval between successive principal-output pulsesl
  • a nerve-cell membrane is a rectifier with a limiting resistance for outward currentflow of approximately. M thatifcr inward flow.
  • a healthy nerve is'a chain of cells, each of which has. properties. resembling an electric oscillating circuit 'with a self-contained source c.
  • a finite, but relatively short, interval of time is required in which to excite a nerve this interval ofitl'me 'willdepend upon the magnitude of the applied sign'al (the greater the applied signal,.the' shorter the time for excitation); once excited, the response ofthe nerve is substantially the same; more or less regardless of the amplitude of the applied signal; and, once excited, the'nerv'e exhibits an absolute refractory period followed by'a relative refractory periodfiduring which time a'repetition of the same applied signal will have no excitative efiect on the nerve.
  • the electrical resistance of a nerve, in the conductive direction; and for the period after signalapplication and before excitation, is low, very much lower than skin resistance, even much lower than the resistance of sweaty or otherwise wetted skin.
  • el Nerves terminate at the skin; and particular nerve systems terminate at particular points at the skin'(i. e. at particular parts over the body).
  • the b'o dy under treatment may be inserted directly between a manually manipulable applicator (548' and one of the other bodycontact electrodes (6- 5l--52) alternatively, the operatorrnay'graspone of the electrodes, say, the manually manipula-ble electrode (5-48) while the patientstands'on or is otherwise in contact with the otlier electrode (65I' 5 2).
  • the operator may then use his fingers or hand" to contact the desired parts of the patients body; thusinterposing parts ofhis own (theoperators) y' n the secondary circuit "of the apparatus.
  • each viscus is connected with the surface of the body through afferent (sympathetic) nerves.
  • afferent nerve viz. parasympathetic nerve, corresponding to a motor nerve for the skeletal system.
  • the present invention is, in effect, a nerve modulator (i. e. it will stimulate via a nerve), and when applied to these areas in which the threshold is lowered, the system of the invention will produce pain when it does not affect adjacent areas supplied by nerves from other spinal segments. By so stimulating these areas, the system of the invention effects a change in nerve action in the viscus itself.
  • cervical 3 will be understood to refer to the third cervical nerve (of which there are eight on each side of man).
  • the cervical nerves branch out from the upper or neck portions of the vertebra; the dorsal or thoracic nerves branch out from the vertebra below the cervical nerves; the lumbar nerves branch out below the dorsal nerves; and the sacral nerves branch out from the lower portions of the vertebra.
  • the procedure is to affect the organ or organs through the nervous system; this treatment may necessitate a particular po larized position of the reversing-switch means (IL-49) depending upon the observed meter in- 10 dications (on one of the meters 28-50-55), depending upon which equipment is employed).
  • IL-49 reversing-switch means
  • One position of the reversing switch means (IT-49) may be termed a positive position (corresponding to the generation of positive initial surges of the wave trains), and the other position of the reversing-switch means H49) may be termed a negative position (corresponding to the generation of negative initial surges of the wave trains).
  • a negative meter reading may be obtained for a positive position of the reversing-switch means, and a positive meter reading may be obtained for a negative position of the reversing-switch means.
  • a given adjustment of the charge-control means (16-31) may result in changing a positive meter reading to a zero reading, or in changing a negative meter reading to zero-
  • the meter reading, the potentiometer settings, and the switch polarity settings may all be correlated with the healthy state of particular internal organs examined by the referred-pain method, so that upon a diagnosis any deviation from .these correlated findings may indicate the health condition of the particular organ thatis affected. Often this trouble or health condition will be evidenced by a referred pain which merely serves to check the meter observations.
  • the method of treatment contemplates applying appropriately polarized stimulation in the abovedescribed manner, thereby tending to effect the desired correction in the meter reading for the organ under consideration.
  • the meter indication may be visibly altered in a single treatment (indicating a corresponding improvement in the health condition of the treated organ) for with a given setting of the charge control (l6--31) and with a given polarity setting of the reversing-switch means (l149), the meter may be observed to swing from what may be termed an unhealthy indication in the direction of the expected normal or healthy indication.
  • an electrical-capacitor means connected to said capacitor for charging said capacitor, a transformer including aninput and an output, means connectingvsaid inputto said capacitor, said connecting meansincludingv'a mechanical interrupter and drive means therefor providing a timed switching operation at the in put-of said transformer ata; repetition rate of the order of 10 to 20 per second, and body applicator means comprising a'gas-filled tube having a dielectric envelope and aniinterior'electrode con-' nected to the output of said transformer.
  • an electrophysica1neurostimu'lator of the characterindicated-an electrical capacitor means connected to said capacitor for charging said 'capacitor, a transformer'includingan input and an output, means connecting saidinput, to said capacitor, said connecting: :means including electronic switching means havingiza 'controlprovidin a timed switching operation at'ithe-input of said transformer-at a repetition rate tof the order of 10 to 20 per second, and-body applicator means comprising a gas-filledtube havingxza dielectric envelope and an-interiorelectrod'e' connected to the output of saidtransformer.
  • pulseegenerator means including an telectrica-lqcapacitor, means connected. to said capacitorforrcharging said capacitor,- electrical. impedance means, means com:
  • said connecting means including switching means having a control providing atimed switching operation at said con-.
  • nection to said impedance means at. a repetition rate oith'e orderof .10 to 205perrsecond, the rise time of-the principal-pulse output of said genera,- tor means being ofthe order 'of .microsecom'ls,v and body-'applicatonmeans. including .two separate' electrodes connected" respectively across :at-

Description

June 9, 1953 Filed Oct. 5,
J. BATROW 2,641 ,259
ELECTROPHYSIOTHERAPY APPARATUS 1948 2 Sheets-Sheet 1 FIG. l.
VOLTAGE I 44f INVENTOR JOHN BATROW FIG. l0.
ATTORNEY J. BATROW ELECTROPI-IYSIOTHERAPY APPARATUS June 9, 1953 2 Sheets-Sheet 2 INVENTOR Filed 001;. 5, 1948 m M .w B N m N HMW A Patented June 9, 1953 UNITED STATES PATENT OFFICE ELECTROPHYSIOTHERAPY APPARATUS- John Batrow, Branford, Conn., assignor to Bartow Laboratories, Inc., Branford, Conn., a. corporation of Connecticut Claims.
This invention relates to electro-physiotherapy, and this application is a continuation-in-part of my application, Serial No. 577,296, filed February 10, 1945. This application discloses circuit improvements not disclosed in said application Serial No. 577,296, now abandoned.
It is the general object of the invention to provide improved means to check for pathology and for correcting the cause when determined.
It is another object to provide improved nervestimulating means that may excite nerves at a repetition rate that is below the normal impulse rate of nerve action, whereby the excited nerve may have time to recover between successive excitations, the rate being sufficiently fast to accomplish results within a reasonable time.
It is a further object to provide an improved electro-therapy apparatus which may utilize relatively high voltages for nerve excitation and which may, nevertheless, be applied with complete safety to the human body more or less regardless of the area of close contact with the skin and also more or less regardless of the sweat condition of the skin.
It is still another object to provide an improved electro-therapy apparatus relatively steepwalled initial surges or pulses of current may be induced in a body so that relatively deep penetration of the electrical impulses may take place.
Other objects and various further features of the invention will be pointed out or will occur to those skilled in the art from a reading of the following specification in conjunction with the accompanying drawings. In said drawings, which show, for illustrative purposes only, preferred forms of the invention:
Fig. 1 is a schematic diagram of an electrophysiotherapy apparatus embodying principles of the invention;
Fig. 1a graphically illustrates the time variation of voltage, characteristic of a wave train produced by the apparatus of Fig. 1; and
Fig. 2 schematically shows alternative apparatus incorporating features of the invention.
My improved equipment is designed to excite, stimulate or modulate upon the nervous system of the body. While the complete physical process of such stimulation and modulation has not yet been established to the satisfaction of all, it is possible that the process in accordance with which my improved equipment is believed to affect the body may be based upon one or more of the following premises:
1. That cellular membrane behaves like manmade electric condensers, and that the membrane capacitance is very high.
2. That myoneural junctions and synaptic connections between neurons are poled or directional in conduction of excitations.
3. That chemical status of cells or organs is determined by the hydrogen-ion concentration.
4. That the autonomic nervous system is the regulating mechanism which maintains ionic balance of cells, or hydrogen-ion concentration.
5. That when the pH of cells or tissue is minus, the cellular membranes, or electrical condensers, are charged negatively; when the pH is plus, the cellular membrances are charged positively.
6. That when these membranes, or condensers, are charged, the organs and tissues are in a negative electrical state and, when discharged, they are in a positive electrical state.
7. That many diseases with metabolic disturbances are the result of this negatively charged or positively charged condition of cells, tissues, and organs; when there is a feeling of well being, the anabolic and catabolic phases of metabolism are regulated within physiological limits as indicated by basal metabolic-rate instruments.
8. That the autonomic nervous system consists of two major branches-sympathetic and parasympathetic; the sympathetic system positively changes the organs (catabolic action), and the parasympathetic system negatively charges the organs (anabolic action).
9. That both branches of the autonomic nervous system are antagonistic to one another in action; the frequency of charge or discharge of the cells, tissues, and organs must be at a rate so as to overcome the antagonistic action of the nerve-causing disturbance.
10. That this antagonistic action manifests itself in the living, and not then if one is under the influence of drugs or other inhibitors; therefore, what is the proper frequency is based on this fact.
11. That the indication of overcharge negatively results in hypersensitivity, and overcharge positively results in hyposensitivity; the action potential must be varied to meet the status quo of the nerve or nerves stimulated.
12. That the current flow and the current density at the skin must be of relatively low amplitude to avoid burns, shocks, or other unpleasant sensations.
My improved equipment therefore includes improved means essentially for the purpose of eifecting the charging negatively or the charging positively, as may be required, of cellular membranes of the human body, which cellular membranes, as indicated above, behave after the manner of man-made condensers.
My improved equipment is constructed and arranged to bias the membrane condensers as to polarity and to return them to that state required for normal health or at least to attempt the alleviation of a given pathological condition. Novel indicating means may be employed to assist in making the necessary determinations.
Referring to Fig. 1 of the-drawings, my invention is shown in application to a mechanically interrupted system for applying pulse excita tions to the body between a pair of electrodes 56. One of the electrodes"5''6 may be a gas-filled discharge device having an envelope of non-conducting material and for direct application to the body. In the form shown, the electrode or applicator 5 is such a gas-filled discharge device and is shown to comprise a relatively extensive Winding of non-conducting tubing, such as glass tubing, communicating with a handle portion 1. A single electrode 8 may be supported within the handle portion 1, and the entire device may be 'filled with an ionizable inert gas, such as neon, under relatively low pressure. The other body-contact electrode may be a metal plate, either for directcontact as by clamping to a'given part of the body, or for use as a platform on which-the patient may stand.
As indicated generally above, the means for stimulating a body by the electrodes 5 6-may include a capacitor 9 that is suitably charged. In the form shown, the equipment'is designed to operate from a source of alternating current; the charging means for capacitor 9 may therefore include full-wave rectifier means with suitable smoothing elements ll, I2, and 13 to apply a smoothed direct-current potential across a load resistor l4. Potentiometer means 15-46 may be employed for adjusting the magnitude of direct-current utilized to charge the capacitor 9, and in order toprovide' forthe selective reversal of polarity of this charge, there may be a reversing switch I! between the resistor l4 and the capacitor 9.
In accordance with the invention, the capacitor 9 is intermittently discharge through suitable diiferentiating means for application of pulses (characterized by relatively sharp upswings or leading edges) across the bodycontact electrodes -6. means may be a step-up transformer, such as the autotransformerv l8, and the capacitor 9 may be directly connected to the primary of the autotransformer l8 through a mechanical contactor or interrupter IS. The contactor [9 may include a pair of opposed conductive segments (connected to each other) to be contacted periodically by a-continually rotating contact finger 2|, and the finger may be drivenby a motor 22. The contactor I9 may include, two further opposed conductive segments-23,- which are also connected to each-other and which may be selectively utilized instead of the segments 20, depending upon the selected positioning of a switch 24.
It will be understood that with the frequent contacting called for'by operationinaccordance with the invention, the discharge. of capacitor 9 may be accompanied by such surges as to draw arcs between finger 2| and segments 29. Such arcs may pit the surfaces of segments 20. and thus impair their reliability-of operation. The life of a contactor such as the contactor 19 may then be extended by-shifting the switch 24 so as to employ segments 23 (inplace of The differentiating segments 20) for the discharge of capacitor 9.
The single electrode 8 of the gas-discharge device 5 may be connected to one side of the secondary of transformer I8, and the secondary circuit may be completed through the body to ground, as through a number of selectively insertable resistances 25-2 6--2I between the electrode 6 and ground. For purposes which will later be clear, the resistances 25262'l form .part of what I term a meter or indicator circuit to be employed for quantitive diagnostic and pathological purposes. This meter circuit is shown to include a current-responsive device 28. which may be merely an ammeter bridging the resistance 2'!, and the effective resistance of the element 2'! may be reduced as desired by selectively inserting further shunt resistances 29-30, as by operation of switches 3l32. The meter circuit is completed by a further branch including a spark gap 33 and a resistor 34, bridging the rest of the described meter circuit between the electrode 6 and ground.
In operation, the patient may stand upon the electrode 6 with preferably bare or with stocking feet, and the manually unanipulable electrode or applicator 5 may be applied to certain parts of the body, depending upon the organ to be treated or examined, as will laterfbe clear. The capacitor 9 is normally charged and, as soon as the contact finger 2| contacts one of the conducting segments 29, there may be a direct connection to the primary of the transformer 19 so as to cause animmediate lowresistance discharging of the capacitor 9. The transformer [8 will be understood to provide not only a vastly increased step-up in mag nitude of voltage, as compared with the voltage discharged from capacitor'9, but also in effect to differentiate the wave form of the'discharge from capacitor 9. Since the discharge represents a sudden break, the differentiated output appearingin the secondary of the transformer 18 may be characterized by relatively highvoltage surge that may attain its maximum amplitude in a relatively short time. Actually, thisfirst surge is merely the beginning of a highly damped oscillatory wave train (see Fig. la) that is repeatedly produced once for every discharge of the capacitor 9. The, meter circuit may provide the principal component of the high resistance responsible for fast damping, thereby rapidly making available a relatively long quiescent period, in order to permit a certain amount of nerve recovery before application of the next succeeding stimulation impulse. .Since the capacitor 9'ischarged with directcurrent of a given polarity, it will be appreciated that the initial surge of the output of transformer I8 will be of a polarized sense that: refiects the polarization of capacitor 9. Thus, if the terminal 9 is charged to a potential greater than that of terminal 9", the initial surge in the secondary of the transformer I8 may be negative with respect to ground (i. e. image or reverse of the wave form of Fig. la). On the other hand, with the reversing switch I] thrown, the potential at terminal 9 will exceed that at terminal 9', and the differentiated output appearing in the secondary of transformer [8 may include an initial positive (with respect to ground) surge for each discharge operation of the interrupter 19 (as in Fig. la). As indicated generally above, it is not known what mechanism produces the beneficial results of the invention, but it is thought that. the relatively rapid initial polarized voltage surge'in the output of the transformer may be able to cause electrical penetration within the body where a more slowly rising wavewould otherwise be blocked by polarization effects in the nerves. The rapid rise of current transmitted to the body may also be made possible by the non-linear impedance properties of the gas-discharge applicator 5. When excited sufficiently to render the gas conductive, the conducting gas and the fluids within the body become, in effect, opposite plates of a capacitative coupling element in the secondary circuit (which in,- cludes the body); the glass of electrode 5 and the skin of the body constitute the dielectric of the capacitative coupling. The capacitance of this coupling may present a relatively low impedance to the very high frequency components of the initial surge of the stimulating wave train.
It has been indicated generally above that my preferred repetition rate for the successive discharging of capacitor 9 is 10 to 20 per second. In practice, a repetition rate of 12 or 13 per second has been found to produce very satisfactory results. These interruption rates will be observed as being less than the normal impulse rate of nerve action, which is from 40 to 100 per second. This fact suggests that myapparatus may permit the nerve sufficient timeto recover between successive applications of current surges, and that my preferred rate is rapid enough to accomplish results before the stimulating effect of each pulse may have been completely dissipated.
In Fig. 2, I show a modified form of the invention in which completelyelectric means are employed not only for the generation of stimulating impulses but also for periodically discharging a capacitor 46. The means for charging the capacitor 40 may employ half-wave rectifier means 4| in conjunction with smoothing elements 4242'-43, and the voltage output of rectifier 4| may be controlled by a variable trans former 31. For the protection of the system I prefer that ample time be allowed for the filaments of the vacuum tubes to warm up prior to initiating the normal operation of the system. To this end, full voltage cannot be applied across the rectifier 4| until operation of a delayedaction starting relay 44. The relay 44 may be energized by an indirectly-heated full-wave rectifier 45, as when emission becomes estabilshed in rectifier 45; and, of course, the solenoid of relay 44 will thereafter remain energized as long as the required voltage is applied to the system.
In the form shown in Fig. 2, I employ a gasdischarge device, such as a thyratron 46, periodically to apply to capacitor 40 the charging voltage from the circuit of rectifier 4|, and then to cut off the application of such charging voltage in order that capacitor 4|] may discharge into the primary circuit of an output transformer. Upon firing the thyratron 46, it will be understood that the cathode of thyratron 46 will be at the high anode potential, so that the full voltage output of rectifier 4| (as modified by the setting of potentiometer 39) may be applied across capacitor 40 and across a small part of a bias potentiometer 38. Due to the high capacitance of capacitor 4|], there may then be such a surge of charging current as to produce a quenching or cut-off voltage in bias potentiometer 38 for almost immediately quenching the thus cut off, capacitor 40 may discharge directly into, the primary of transformer 41.
The secondary of the transformer 41 may include a connection to a manually manipulable gas-filled applicator 48, which may be generally similar toithe applicator 5 described in connection with Fig. 1. Again, reversing-switch means 49 may serve to reverse polarity of the capacitor discharge as it is applied to the primary of transformer 41, thus providing a means for control of the direction of the initial surges of the wave trains generated in the secondary circuit of transformer 41. If desired, meter or indicator means 50 and a'further body-contact electrode 5| may be included in the secondary circuit of the transformer 41. Alternatively, it maybe preferred to employ a meter circuit as described in connection with Fig. 1 such a meter circuit may employ a body-contact electrode 52 connected to ground, on the one hand, through a resistor 53 and spark gap 54 and, on the other hand, through a meter 55 associated with a plurality of adjustably selectable resistances.
Operation of the switching means 46 for pcriodically discharging the capacitor 40 may employ any desired technique that provides periodic control or firing impulses for the grid circuit of the thyratron 46, as via the coupling transformer 56. In the form shown, I assume a source of alternating current having a frequency of n cycles per second, and I employ a cascaded frequency divider of 0: stages, such that n/zc may provide the desired repetition rate of discharging capacitor 40. It will be recalled that this desired rate is of the order of '10 to 20 per second; for the 60 cycle case, therefore, a five-stage frequency divider may provide a desired excitation rate of 12 per second.
The frequency divider of Fig. 2 may operate from a full-wave rectifier 5 8, which may provide through its cathode circuit a suitable B supply for a pulse-generating tube 66, and which through one of its anode circuits may provide bias control for the grid of tube 60. By suitable adjustment of the bias resistor 51, a single short triggering impulse (i. e. one for every full cycle of the supply voltage) may be applied to the control electrode of tube 66. The tube 60 will thus be rendered conductive once every cycle of the supply voltage. For each such conduction of tube 60 there may be a control impulse or surge derived from a potentiometer 6| in the cathode circuit of tube 60, for direct application to each of the tubes 6263-64-65-66 of the five-stage frequency divider.
The load of each of the tubes 62 to 66 may be in its particular cathode circuit and, from left to right in the sense of drawing, each oathode load resistor of each tube is coupled to the grid of the next-succeeding tube stage. Each of the cathode circuits of the switching tubes 62-66 may be bridged by a capacitor, such as the capacitor 61 across the load resistor 66 in the circuit of tube 62, so that upon conduction of a switching tube, such as the tube 62, the voltage appearing across its load resistor (68) may charge its load capacitor (61). The charge on capacitor 61 may be held sufiiciently long to maintain a reduced bias on the control grid of the next-succeeding tube stage 63, so that upon generation of the next pulse (corresponding to the next cycle of the supply voltage), as derived from potentiometer 6|, there may be a starting of tube 63 to the exclusion of the other tubes firing of thyratron 46; when thyratron .46 is 7 62, 64, 65, and 66. Upon conduction of tube 63,
the voltage appearing across .theloadxresistor 89 is available Ito 'charge: capacitor 10' for appropriate reduction of the. bias on the control grid of theinext succeeding stage 64; and, of course, the next succeeding. impulse maybe: effective to operate the tube GLtothe. exclusionof the other switching tubesfl til, and, 66.
ln like manner,..tubes =65ian'd. 68 will. be successively operated for. the nexttwo succeeding cycles ofv the supply voltage; and, upon conduction of the laststage 66, acontrol-impulse may be fed to the primary of the coupling transformer 56, as through a coupling capacitance .H, for the controlled firing of thyratron 45 and, hence, for the generation-of axwave train for application to 'thebod y between electrodes and..5l or between electrodes lil and 52, depending upon the connections employed. The switching or tubetrlggeringsequence maybe rendered self-recycling by coupling the cathode-circuit output" of tube 66 back to the control grid of the first switching stag-e62,- as will be clear. It will thus be seen that-for every timing impulse supplied a) the thyratron 46-, there will have been five successive operations ofthe various stages of the frequency divider and that these stages will have beenoperatedby five successive cycles of the supply voltage. For a GO-cycle supply, the thyratron 46 will-thusbe'fired at a repetition rate ofl2' per second.
- As indicated, generally above, it is not known exactly what mechanism is involved when a body is placed between the manually manipulable gasfilled applicator (5, 48') and one of the other body-contactelectrodes. It'is known, however, that th'e Wave-train generated upon each discharge'of acapacitor'w, 40-) is characterized by an extremely steep-walled initial surge of voltage to a"relatively high magnitude and that this surge, is followed'by a highly damped oscillationwhi ch decays after-some 6 or 8 swings; the fre quency of the swings may be from 2,000 to 5,000 cycles per second, depending upon the inductance capacitance constants of the step-up transformer 18, '41 and of various other elements in the circuit; and, upon the first half-cycle of this oscillation, there, always appears to'be superimposed a further highly damped oscillation of higher frequency (at least 6 or 8' times the characteristic 2,000 to 5,000 cycles per second). As far as, is, known ofthe p-ulse characteristics of my device, it is preferred that the rise time of the principal pulse output shall be of the order of 50- microseconds, with a rise to'75 percent of the peak of this pulse in an interval of the order of 20 n icroseconds; It is known that the preferred repetition rate of 12 per second (or at least between 10 and 20" per secondlis below the normal impulse rateof nerve action; for these rates, a preferred duty cycle of; the order of 10" i's-tlius indicated. By duty cycle" is meant the fraction al relation between the time duration of the principal outpu't'- pulse and the time'interval between successive principal-output pulsesl It is known that a gaseousdischarge applicator, such asthe applicators and'28', may provide a convenient means of applying current to the body, due. to the -substantially purelycapacitance characteristics ofthese applicators when so appliedto the body; thesecharacteristics make-possible current distribution more or less independent ofthe area 0t close contact with the skin and more or less independent of the sweat condition of: the skin, sincethe skin itselr is subjected to little or no actual flowotcurrent; Y I I The nature of current conduction within. the body is admittedly obscure, particularly-when capacitatively subjectedttothe short high-peaked pulses produced. by applicants'e'quipment; However, the following is believed to be well-established:
a. A nerve-cell membrane is a rectifier with a limiting resistance for outward currentflow of approximately. M thatifcr inward flow.
' b. A healthy nerve is'a chain of cells, each of which has. properties. resembling an electric oscillating circuit 'with a self-contained source c. A finite, but relatively short, interval of time is required in which to excite a nerve this interval ofitl'me 'willdepend upon the magnitude of the applied sign'al (the greater the applied signal,.the' shorter the time for excitation); once excited, the response ofthe nerve is substantially the same; more or less regardless of the amplitude of the applied signal; and, once excited, the'nerv'e exhibits an absolute refractory period followed by'a relative refractory periodfiduring which time a'repetition of the same applied signal will have no excitative efiect on the nerve.
d. The electrical resistance of a nerve, in the conductive direction; and for the period after signalapplication and before excitation, is low, very much lower than skin resistance, even much lower than the resistance of sweaty or otherwise wetted skin.
el Nerves, or at leastthe nerves of present concern, terminate at the skin; and particular nerve systems terminate at particular points at the skin'(i. e. at particular parts over the body).
In use, the b'o dy under treatment may be inserted directly between a manually manipulable applicator (548' and one of the other bodycontact electrodes (6- 5l--52) alternatively, the operatorrnay'graspone of the electrodes, say, the manually manipula-ble electrode (5-48) while the patientstands'on or is otherwise in contact with the otlier electrode (65I' 5 2). The operator may then use his fingers or hand" to contact the desired parts of the patients body; thusinterposing parts ofhis own (theoperators) y' n the secondary circuit "of the apparatus.
Inusing my improved equipment, the referredpai'n' method of'diagnosis is employed. Referred pains can only beunderstood when'the organ is carefully studied with reference to its embryologic development'in whichcase it will be seen thatlth'eusual Visceral pain follows thesegmental relationshipwhich determined the innervation in early development life. Heads clinical investigations' are "of practical importance" and have :beenverified and are oftenused with my improved equipment. .Below are listed some of Heads charted areas of important organs, which have been verified with my improved equipment:
Heartcervical 3,, cervical4, dorsal 2 to dorsal8; llun s-cervical 3, cervical a, dorsal 4 to dorsal9; Stomach -.d.orsal 7 to dorsal,9;. v I Intestines-dor'sal 9 to dorsal 12; Liver'ce.rvical.3, cervical '4, dorsal: 7 to dorsal 10; Kidney dorsal ll to lumbar. l-;
Bladder'asacral 8 to sacral 4.
The above listing is helpful in. illustrating d agnostic use of the; invention in visceral neurology." The visceral organs have" previously been 'shown" (syn-cad; int'eralia) to be served by'part'iculannervef systems; andin" each of these nerve systems there is an aflerentnerve'mz:
sympathetic nerve, corresponding to a senso y nerve for the skeletal system) and an efferent nerve (viz. parasympathetic nerve, corresponding to a motor nerve for the skeletal system). According to visceral neurology, each viscus is connected with the surface of the body through afferent (sympathetic) nerves. When a viscus is diseased, the threshold of response in these nerves (serving this particular viscus) is lowered,
so that under various stimuli the areas connected with that viscus show pain more readily than they ordinarily would; such pain has been termed a referred pain. The present invention is, in effect, a nerve modulator (i. e. it will stimulate via a nerve), and when applied to these areas in which the threshold is lowered, the system of the invention will produce pain when it does not affect adjacent areas supplied by nerves from other spinal segments. By so stimulating these areas, the system of the invention effects a change in nerve action in the viscus itself. With a knowledge of the viscera, and of the skin-terminated nerve systems associated with each particular viscus, it will be clear that one may diagnose a particular visceral abnormality and that one may therapeutically stimulate the abnormal viscus.
Now the above chart lists nerve systems of the character above-discussed, serving certain vicera. The term cervical 3 will be understood to refer to the third cervical nerve (of which there are eight on each side of man). The cervical nerves branch out from the upper or neck portions of the vertebra; the dorsal or thoracic nerves branch out from the vertebra below the cervical nerves; the lumbar nerves branch out below the dorsal nerves; and the sacral nerves branch out from the lower portions of the vertebra.
Specifically, and to illustrate, if the heart of the patient is in a pathologic state, we find that the patient will feel pain when the manually manipulable electrode 5 or when the operators finger is placed on the skin ending of the cervical-3 nerves. As will be seen from the above listing, this will not be a conclusive diagnosis, because the heart, lungs, and liver are all served by the cervical-3 nerves. However, it will be noted that no two organs are served by the same combination of nerve systems, and that therefore the illustrated referred-pain method may serve for a definite identification of the abnormal organ.
The theory upon which my treatments are based is the reciprocal reflex relationship which exists between dermal or somatic and visceral or splanchnic structures. This reciprocal relationship is closer than is generally realized. For many years, physicians have attempted to treat visceral disease by applications to the surface of the body. The study of pathologic physiology gives us definite for such therapeutic measures, especially when using the proper electrical modulation upon the nervous system.
After locating the organ responsible for the causes of the disease by the diagnostic method outlined above, and also after taking advantage of the existing methods of checking to verify the findings when possible (methods such as blood count, urine analysis, X-ray and fluoroscope study, etc.), the procedure is to affect the organ or organs through the nervous system; this treatment may necessitate a particular po larized position of the reversing-switch means (IL-49) depending upon the observed meter in- 10 dications (on one of the meters 28-50-55), depending upon which equipment is employed). One position of the reversing switch means (IT-49) may be termed a positive position (corresponding to the generation of positive initial surges of the wave trains), and the other position of the reversing-switch means H49) may be termed a negative position (corresponding to the generation of negative initial surges of the wave trains).
Although the phenomenon has not been identified or fully explained, it is known that for a given setting of the charge control (potentiometer l6, transformer 31), that is, for a given charge on". the capacitor (9-40), and for application of the body-contact electrodes between given parts of the body, a positive meter indication may be obtained for a positive position of the reversing-switch means (ll49); in like manner, a negative meter reading may be obtained for a negative position of the reversingswitch means (|l49). Similarly, for the same instrument settings, but between different parts of the body, or for another health condition of the organs affected by contact with the same parts of the body, a negative meter reading may be obtained for a positive position of the reversing-switch means, and a positive meter reading may be obtained for a negative position of the reversing-switch means. Furthermore, depending upon the parts of the body contacted, and depending upon the condition of the organ thereby under examination, a given adjustment of the charge-control means (16-31) may result in changing a positive meter reading to a zero reading, or in changing a negative meter reading to zero- The meter reading, the potentiometer settings, and the switch polarity settings may all be correlated with the healthy state of particular internal organs examined by the referred-pain method, so that upon a diagnosis any deviation from .these correlated findings may indicate the health condition of the particular organ thatis affected. Often this trouble or health condition will be evidenced by a referred pain which merely serves to check the meter observations. Knowing the direction in which the meter reading must be caused to change in order to produce a healthier state in a diseased organ, the method of treatment contemplates applying appropriately polarized stimulation in the abovedescribed manner, thereby tending to effect the desired correction in the meter reading for the organ under consideration. Often, the meter indication may be visibly altered in a single treatment (indicating a corresponding improvement in the health condition of the treated organ) for with a given setting of the charge control (l6--31) and with a given polarity setting of the reversing-switch means (l149), the meter may be observed to swing from what may be termed an unhealthy indication in the direction of the expected normal or healthy indication.
The following diseases, among others, have been treated with my improved equipment under close medical supervision, with good results; multiple sclerosis; peripheral neuritis; paralysis agitans; Mnieres disease; arthritis deforman's; hypertension; hypotension; hyperthyroid; hypothyroid; and osteo-arthritis While the invention has been described in considerable detail and preferred forms of apparatus illustrated and described, and preferred procedure indicated, it is to be understood that various changes and modifications may be made within pacitor, said-connecting means includingswitch-w ing means having a control providing a timed; switching operation at the input of 1 said transformer at a repetition rateof the'order 'of to '20, per second, and body-applicatorimeanscomprisingagas-filled tube having'a dielectric envelope and an interiorelectrode connected to the output of said transformer; e a
2. In an electrophysical neurostimulator of the character indicated, an electrical-capacitor, means connected to said capacitor for charging said capacitor, a transformer including aninput and an output, means connectingvsaid inputto said capacitor, said connecting meansincludingv'a mechanical interrupter and drive means therefor providing a timed switching operation at the in put-of said transformer ata; repetition rate of the order of 10 to 20 per second, and body applicator means comprising a'gas-filled tube having a dielectric envelope and aniinterior'electrode con-' nected to the output of said transformer.
3. In an electrophysica1neurostimu'lator of the characterindicated-an electrical capacitor; means connected to said capacitor for charging said 'capacitor, a transformer'includingan input and an output, means connecting saidinput, to said capacitor, said connecting: :means including electronic switching means havingiza 'controlprovidin a timed switching operation at'ithe-input of said transformer-at a repetition rate tof the order of 10 to 20 per second, and-body applicator means comprising a gas-filledtube havingxza dielectric envelope and an-interiorelectrod'e' connected to the output of saidtransformer.
4. In an ele'ctrophysicalneuronmsculan-stimulater of the character indicated, pulseegenerator means-including an telectrica-lqcapacitor, means connected. to said capacitorforrcharging said capacitor,- electrical. impedance means, means com:
necting said capacitor across at least a part :01 said impedance means, said connecting meansincluding switching means having a control providing atimed switching operation at said con-.
nection to said impedance means at. a repetition rate oith'e orderof .10 to 205perrsecond, the rise time of-the principal-pulse output of said genera,- tor means being ofthe order 'of .microsecom'ls,v and body-'applicatonmeans. including .two separate' electrodes connected" respectively across :at-
least a part otsaid 'impedance means, anda dielectric envelope filled witha conductive gas electrically' inserieswith one .of said electrodes.
5, 'An electroph-ysical stimulator according "to claim 4, in which therise. to percent :of the pea}; .value of -the principal-pulse. output of said generator means is of the order of 20 microseconds.
JOHN BA'IR'OW.
mama. omem the file of this patent v V V UNITED STATES PATENTS Number OTHER'RE FERENCES 1 .TheBritish. Journal of Physical Medicine for November 1941, pages 153-4. Copy in Scientific Library.
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US3077884A (en) * 1957-06-13 1963-02-19 Batrow Lab Inc Electro-physiotherapy apparatus
DE1181826B (en) * 1959-11-09 1964-11-19 Dr Med Willy Seuss Electro-therapeutic device for analgesic manipulation of the nerves and treatment of diseases using an electric field
US3160159A (en) * 1960-01-04 1964-12-08 Hoody Jusha Borisovich Device for inducing sleep
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US20090198293A1 (en) * 2003-12-19 2009-08-06 Lawrence Cauller Microtransponder Array for Implant
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