WO2007102957B1 - Skin care compositions including hexapeptide complexes and methods of their manufacture - Google Patents

Skin care compositions including hexapeptide complexes and methods of their manufacture

Info

Publication number
WO2007102957B1
WO2007102957B1 PCT/US2007/002473 US2007002473W WO2007102957B1 WO 2007102957 B1 WO2007102957 B1 WO 2007102957B1 US 2007002473 W US2007002473 W US 2007002473W WO 2007102957 B1 WO2007102957 B1 WO 2007102957B1
Authority
WO
WIPO (PCT)
Prior art keywords
extract
composition
argireline
recited
skin
Prior art date
Application number
PCT/US2007/002473
Other languages
French (fr)
Other versions
WO2007102957A2 (en
WO2007102957A3 (en
Inventor
Natalie Dilallo
Original Assignee
Guthy Renker Corp
Natalie Dilallo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guthy Renker Corp, Natalie Dilallo filed Critical Guthy Renker Corp
Publication of WO2007102957A2 publication Critical patent/WO2007102957A2/en
Publication of WO2007102957A3 publication Critical patent/WO2007102957A3/en
Publication of WO2007102957B1 publication Critical patent/WO2007102957B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212Face masks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755Gymnosperms [Coniferophyta]
    • A61K8/9767Pinaceae [Pine family], e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02Preparations containing skin colorants, e.g. pigments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Abstract

Skin care compositions disclosed herein include, at a minimum, safe and effective amounts of at least one wrinkle reduction agent, which is a hexapeptide, and a natural exfoliating complex. The skin care compositions provide natural skin exfoliation, reduce fine lines and wrinkles, and improve skin elasticity and firmness.

Claims

AMENDED CLAIMS received by the International Bureau on 29 November 2007 (29.11.2007).1. A skin care composition, comprising: a) a muscular contraction inhibiting agent comprising an effective amount of acetyl hexapeptide Argireline®, whereby said acetyl hexapeptide specifically targets the repeated, biomechanical, muscular contractions of facial expressions by functioning to reduce the intensity of these muscle contractions, and further reduces the release of catecholamines and limits the production of SNARE complexes; b) an exfoliation component comprising an effective amount of Ahnfeltia Concinna extract, whereby said Ahnfeltia Concinna extract increases cellular turnover and density of collagen bundles of the upper dermis of the skin; and c) at least one additional peptide component selected from the group consisting of Serilesine™(Hexapeptide-10), Palmitoyl Tripeptide-3, tetrapeptide-3, pentapeptide-3, tripeptied-1, palmitoyl oligopeptide, palmitoyl peptide-3, Tripeptide-
1. and actyl tetrapeptide-5; whereby components a), b), and c) work in concert to reduce wrinkles and improve overall skin appearance.
2. A composition as recited in claim 1, further comprising an additional ingredient selected from the group comprising: grapefruit Peel extract, Hydrolyzed Rice Protein, Oxido Reductases, cucumber fruit extract, licorice extract, cola nitida seed extract, Ilex Paraguariensis, fennel fruit extract, Melissa Officinalis leaf extract, mistletoe leaf extract, and Pullulan.
3. A composition as recited in claim of claim 1, comprising Bulyrospermum (Shea) Fruit Butter, Theobroma Cacao (Cocoa) Seed Butter, Lignoceryl Erucate, Trideccyl Trimellitate, Glyceryl Stearate, PEG-100 Stearate, Dipalmitoyl Hydroxproline, Emulsifying Wax, Dimethicone, Mica, Silica, Phenoxyethanol, Salix Nigra (Willow) Bark Extract, Hexapeptide- 10 Serilesine, Argireline®, grapefruit Peel extract, and Ahnfeltia Concinna Extract, whereby said composition is a skin cream.
4. A composition as recited in claim of claim 1, comprising Willow Bark Extract Isostearyl Palmitate, Squalane, Caprylic/Capric Triglyceride, Cetearyl Alcohol
i (and) Ceteareth-20, Stearic Acid, Cetyl Lactate, Triethanolamine, Polycrylamide, C13-14 Isoparaffin, Cyclomethicone, Mica, Silica, Titanium Dioxide, Caprylic/Capric Triglyceride, Cucumis MeIo (Melon) Extract, Musa Sapientum (Banana) Fruit Extract, Vitis Vinifera (Grape) Fruit Extract, Iris Florentina Root Extract, Hibiscus Abelmoschuus, Phenoxyethanol, Hyaluronic Acid, Palmitoyl Tripeptide-3, Hydrolyzed Soy Protein, Argireline®, Ceramide 3, Ceramide 6, Ceramide 1, Phytosphingosine, Cholesterol, Sodium Lauroyl Lactylate, Carbomer, and Ahnfeltia Concinna Extract, whereby said composition is a skin cream.
5. A composition as recited in claim of claim 1, comprising Ahnfeltia Concinna Extract, Argireline™, Serilesine™, Magnesium Aluminum Silicate, Acrylates/CiO-30 Alkyl Acrylate Crosspolymer, Titaniun Dioxide, Iron Oxides, Titanium Dioxide, Mica, Silica, Hydrogenated Lecithin, Isoeicosane, Isostearic Acid, Glyceryl Stearate, Tridecyl Trimellitate, Dimethicone, Cyclomethicone, Polysilicone-1 1, Phenoxyethanol, Melon Extract, Banana Extract, Vitis Vinifera (Grape) Fruit Extract, Iris Florentina Root Extract, and Hibiscus Abelmoschuus, whereby said composition is formulated as a skin foundation.
6. A composition as recited in claim of claim 1, comprising Ahnfeltia Concinna Extract, Argireline™, Serilesine™, Palmitoyl Tripeptide 3, grapefruit Peel extract, Willow Bark Extract, Shea Butter, PEG-8/SMDI Copolymer, Carbomer, Carrageenan, Bisabolol, Neopentyl Glycol Dicaprylate/Dicaprate, Octyldodecyl Neopentanoate, Octisalate, Octinoxate, Butyl Methoxydibenzoylmethane, Benzophenone-3, PEG-4 Olivate, Glyceryl Stearate, Squalane, Cetyl Lactate, Hydrogenated Lecithin, Triethanolamine, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Titanium Dioxide, Silica, Mica, Phenoxyethanol, whereby said composition is formulated as a skin lotion.
7. A composition as recited in claim of claim 1, comprising Ahnfeltia Concinna Extract, Argireline™, Aloe Barbadensis Leaf Juice, Shea Butter, Carrageenan, Bisabolol, PEG-4 Olivate, Sorbitan Olivate, Squalane, Cetyl Lactate, Dipalmitoyl Hydroxyproline, Hydrogenated Lecithin, Dimethylmethoxy Chromol, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide- 1, Phenoxyethanol, White Tea, Green Tea, Saccharide Isomerate, Hydrolyzed Rice Protein, Soybean Protein, Oxido Reductases, Ceramide 3, Ceramide 6, Ceramide I, Phytosphingosine, N-Hydroxysuccinimide-Chrysin, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-3, Cucumber Fruit Extract, Licorice Extract, and Phenoxyethanol, whereby said composition is formulated as a skin cream.
8. A composition as recited in claim of claim 1, comprising Ahnfeltia Concinna Extract, Argireline™, panthenol, Aloe Barbadensis Leaf Juice, Hydroxyethylcellulose, Pentapeptide-3, Serilesesine, Palmitoyl Tripeptide-3, Corn Extract, Licorice Extract, Hydrolyzed Soy Protein, Dimethylmethoxy Chromanol, Green Tea, White Leaf Tea, Tripeptide- 1, hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Phenoxyethanol, Cola Nitida Seed Extract, Ilex Paraguariensis, Fennel Fruit Extract, Humulus Lupulus (Hops) Extract, Melissa Officinalis Leaf Extract, Viscum Album (Mistletoe) Leaf Extract, Chamomilla Reticutita (Matricaria) Flower Extract, Achillea Millefolium Extract, N- Hydroxysuccinimide, Chrysin, Palmitoyl Oligopeptide, Palmitoyl Peptide-3, Acetyl Tetrapeptide-5, whereby said composition is formulated as a serum or semi- viscous gel.
9. A composition as recited in claim of claim 1, comprising Ahnfeltia Concinna Extract, Argireline™, Panthenol, Aloe Barbadensis Leaf Juice, Hydroxyethylcellulose, Pentapeptide-3, Serilesesine™, Palmitoyl Tripeptide-3, Corn Extract, Licorice Extract, Hydrolyzed Soy Protein, Dimethylmethoxy Chromanol, Hydrolyzed Wheat Protein, Tripeptide- 1, Phenoxyethanol, white tea extract, green tea extract, and melon extract, whereby said composition is formulated as a serum or semi-viscous gel.
10. A composition as recited in claim of claim 1, comprising Ahnfeltia Concinna Extract, Argireline™, Panthenol, Aloe Barbadensis Leaf Juice, Algae Extract, Pullulan, Palmitoyl Tripeptide-3, Corn Extract, Dimethylmethoxy Chromanol, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide-1, Phenoxyenthanol, green tea extract, white tea extract, Ascorbic-Acid-2 Glucoside, meolon extract, Mica, Titanium Dioxide, whereby said composition is formulated as a skin mask.
11. A composition as recited in claim of claim 1 , comprising Ahnfeltia Concinna Extract, Argireline™, Palmitoyl Oligopeptide, Ethylhexyl Palmitate, Dimethicone, Ethyhexyl Palmitate, Tribehenin, Soribtan Isostearate, Aluminum Starch Octenysuccinate, Phenoxyethanol, Phospholipid, Tocopheryl Acetate, Retinyl Palmitate, Ascorbyl Palmitate, Benzalkonium Choloride, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Xanthan Gum, Tripeptide-1, Dimethylmethoxy Chromanol, white tea extract, green tea extract, whereby said composition is formulated as a lip treatment composition.
12. A skin care composition, comprising: a) a muscular contraction inhibiting agent comprising an effective amount of acetyl hexapeptide Argireline®, whereby said acetyl hexapeptide specifically targets the repeated, biomechanical, muscular contractions of facial expressions by functioning to reduce the intensity of these muscle contractions, and further reduces the release of catecholamines and limits the production of SNARE complexes, b) an exfoliation component comprising an effective amount of Ahnfeltia Concinna extract, whereby said Ahnfeltia Concinna extract increases cellular turnover and density of collagen bundles of the upper dermis of the skin; and c) a combination of vitamins and lipids comprising Retinyl Palmitate, Tocopheryl Acetate, Ascorbyl Palmitate, Pantothenic Acid, and Phospholipids; whereby components a), b), and c) work in concert to reduce wrinkles and improve overall skin appearance.
13. A composition as recited in claim of claim 12, comprising Ahnfeltia Concinna Extract, Argireline™, Zinc oxide, Pentylene Glycol, Sodium Dihydroxycetyl Phosphate, Beeswax, Ethylhexyl Ethylhexanoate, Polyglyceryl-3 Dicaprate, Triisononanoin, Bisabolol, Meridamate, Octinoxate, Oxybenzone, Melon Extract, Banana Extract, Vitis Vinifera (Grape) Fruit Extract, Iris Florentina Root Extract, Hibiscus, Phospholipids, Retinyl Palmitate, Tocopheryl Acetate, Ascorbyl Palmitate, and Pantothenic Acid, whereby said composition is formulated as a cream.
14. (New) A composition as recited in claim of claim 12, comprising Ahnfeltia Concinna Extract, Argireline™, Aloe Barbadensis Leaf Juice, Magnesium Aluminum Silicate, Shea Butter, PEG-4 Olivate, Sorbitan Olivate, Squalane, Cetyl Lactate, Vitis Vinifera (Grape) Seed Oil, Hydrogenated Lecithin, Gossypium Herbaceum (Cotton), Silica, Nylon 12, Phospholipids, Retinyl Palmitate, Tocopheryl Acetate, Ascorbyl Palmitate, Pantothenic Acid, Hydrolyzed Rice Protein, Glycine Soja (Soybean) Protein, Oxido Reductases, Methyldihydrojasmonate, Phenoxethanol, and Cyclomethicone, whereby said composition is formulated as a cream.
PCT/US2007/002473 2006-02-04 2007-01-29 Skin care compositions including hexapeptide complexes and methods of their manufacture WO2007102957A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/347,587 2006-02-04
US11/347,587 US20060198800A1 (en) 2003-08-14 2006-02-04 Skin care compositions including hexapeptide complexes and methods of their manufacture

Publications (3)

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WO2007102957A2 WO2007102957A2 (en) 2007-09-13
WO2007102957A3 WO2007102957A3 (en) 2007-12-13
WO2007102957B1 true WO2007102957B1 (en) 2008-02-07

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WO (1) WO2007102957A2 (en)

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