WO2008000020A1 - Improved process - Google Patents
Improved process Download PDFInfo
- Publication number
- WO2008000020A1 WO2008000020A1 PCT/AU2007/000879 AU2007000879W WO2008000020A1 WO 2008000020 A1 WO2008000020 A1 WO 2008000020A1 AU 2007000879 W AU2007000879 W AU 2007000879W WO 2008000020 A1 WO2008000020 A1 WO 2008000020A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- keratin
- keratin sample
- abnormal component
- data
- detecting
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N23/00—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
- G01N23/20—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by using diffraction of the radiation by the materials, e.g. for investigating crystal structure; by using scattering of the radiation by the materials, e.g. for investigating non-crystalline materials; by using reflection of the radiation by the materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4742—Keratin; Cytokeratin
Definitions
- a method for detecting a presence of an abnormal component in a keratin sample taken from a subject suffering from a pathological -state comprising the steps of exposing the keratin sample to a swelling substance so as to penetrate the keratin sample thereby producing a derived chemical substance; obtaining data from the derived chemical substance; comparing the data obtained from the derived chemical substance with a second group of data contained in a reference database so as to identify the presence of the abnormal component in the keratin sample; whereby detection of the abnormal component is consistent with a presence of the pathological state in the subject.
- X-ray diffraction analysis has shown that subjects with a plurality of certain types of cancers (colon, breast and prostate) and other pathological states (Alzheimer's disease) produce hair samples that have abnormalities in them.
- the abnormalities are detectable using X-ray diffraction techniques and are consistent with the presence of the pathological state itself.
- X-ray diffraction techniques can identify the presence of an abnormality in hair or other keratin samples, X-ray diffraction techniques are limited in that they do not reveal the nature of the abnormal component (i.e. whether the abnormality represents an inclusion of a chemical substance not normally present or rather a defect in the structure of a keratin fibril for example in the hair) .
- a structural abnormality therefore can have the same proportion of chemical molecules present but differ structurally in geometric orientation of the molecules or their chemical bonding. Therefore, the pathological state can lead to structural changes in chemical bonding in the hair even though the chemical molecules forming the hair are in the same proportion as occurs in normal hair.
- the pathological state can be identified with greater specificity and sensitivity. Identification of the abnormal component means that additional information is then provided about the nature of the pathological state.
- a problem sought to be solved by the present invention is the ability to chemically penetrate a hair sample so as to detect an abnormal component within the hair sample taken from a subject with a pathological state.
- a method for detecting a presence of an abnormal component in a keratin sample taken from a subject suffering from a pathological state comprising the steps of:
- the swelling substance includes formic acid.
- the second group of data is correlated with the presence of the pathological state in the subject.
- the second group of data is causatively associated with the presence of the pathological state in the subject.
- the swelling substance is selected from a plurality of different swelling substances .
- the keratin sample is selected from a plurality of different keratin samples .
- the second group of data is selected from a plurality of different groups of data.
- the derived data and the second group of data are analyzed using a plurality of different methods of comparison .
- the keratin sample can be obtained and analyzed in association with at least one of a pharmacy, a test kit, the subject's home, a health care clinic and a testing laboratory or any convenient location (office, field or barn) .
- the subject is selected from the group consisting of a human, and an animal.
- Figure 1 shows the application of a swelling substance to a keratin sample for use in diagnostic testing.
- Figure 2 shows a plurality of different chemical substances being applied in the alternative to a keratin sample.
- Figure 3 shows a plurality of different keratin samples taken from different subjects with different pathological states (or the same subject with several pathological states) or from a plurality of different mammalian species.
- Figure 4 shows a plurality of different methods of analysis being used to analyze data produced according to the first embodiment disclosed in Figure 1.
- Figure 5 shows the method of analyzing a keratin sample being implemented in use, wherein a sample can be collected from a subject at a health care clinic, a collecting room or using a kit at a convenient location to rhe subject (home, field, barn, etc) .
- Figure 6 illustrates results of SAXS analysis applied to samples treated in accordance with embodiments of the method of the present invention.
- An “animal” is defined as a living organism characterized by the capacity for voluntary motion, sensation and the ingestion of food such as plants and other animals, and which has a non-cellulose cell wall.
- the plurality of different selections and forms pertaining to the invention as claimed include ⁇ .he selections and forms as appearing in the body of the specification.
- “Mammalian species” includes the types of species as appearing in the body of the specification. It can include a human, a pet such as a dog or cat or a variety of other animals with hair.
- a "keratin sample” or “keratin substance” is a sample that is substantially comprised of keratin.
- the keratin substance 16 can include human scalp or body hair and in particular pubic hair, pet hair, animal hair or hair from a member of a mammalian species in general, or other keratin based materials such as nail clippings or an eyelash.
- a "subject” can include a mammalian species.
- a mammalian species can include a human, a pet such as a dog or cat or a variety of other animals.
- Figure 1 illustrates a method of analyzing a keratin sample 16.
- Figure 1 shows a first container 12 which holds a swelling substance 14.
- a keratin sample 16 is taken from subject 11, wherein the subject 11 can include a mammalian species.
- a mammalian species can include a human, a pet such as a dog or cat or a variety of other animals.
- the keratin substance 16 can include human scalp or body hair and in particular pubic hair, pet hair, animal hair or hair from a mammalian species in general, or other keratin based materials such as nail clippings or an eyelash.
- the keratin sample 16 is exposed to the swelling substance 14.
- a derived chemical substance 18 is obtained from application of the swelling substance 14 to the keratin sample 16 whereby the swelling substance 14 penetrates the keratin sample 16.
- the derived chemical substance 18 is collected in the second container 19 (alternatively and without loss of generality only one container need be used) .
- the derived chemical substance 18 located in the second container 19 is then taken to a laboratory 20 at the place of application of the swelling substance 14.
- the laboratory 20 will then use a plurality of diagnostic tests to obtain data 22 which can be compared with data 24 located in a reference database 25 so as to determine if the subject 11 has a pathological state.
- the reference database 25 can be obtained from a plurality of control samples taken from normal subjects and subjects with a plurality of different pathological states.
- the data 22 can be compared with dara 24 in the reference database 25 to determine whether or not the subject 11 has a pathological state, for example if the reference database 25 indicates that the result in question is both correlated and causatively linked to a pathological state then a meaningful comparison can be considered. Additionally zero correlation or no information being provided in rhe case of no association with an abnormal component being present 1 in the derived chemical substance 18 can in certain instances be consistent with an abnormality being a defect in protein folding, that is a structural defect in the keratin sample 16 as opposed to an additional inclusion of a component that may or may not be ordinarily found in the keratin sample 16 such as a metal or other compound (whereby no inclusion is washed out into the derived chemical substance 18) .
- Figure 2 shows an embodiment of the present invention in which the sensitivity or specificity of the method described in Figure 1 is improved by way of changing the swelling substance 14.
- Figure 2 shows a plurality of different swelling substances 14, being Sl, S2...SN.
- the data 22, not shown, is analyzed by comparing the data 22 with the data 24 (from a reference database 25 as seen in Figure 1) so as to select a swelling substance from the set Sl... SN, which is adapted to remove the defect in the keratin sample 16 by either altering the structural nature of the keratin sample 16 so as to restore normal folding and configuration of the keratin sample 16 or by transferring, by way of application of the swelling substance 14 to the keratin sample 16, the component causing the abnormality in the keratin sample 16 to the derived chemical substance 18 (this can involve for example formic acid penetrating and washing out an inclusion from a hair sample) .
- Dithio-Threitol or DTE (Dithioerythritol) and urea or other protein denaturing agents.
- DTE Dithioerythritol
- urea or other protein denaturing agents urea or other protein denaturing agents.
- formic acid other considerations are relevant such as toxicity and in the case of reducing agents the fact that the structure of the keratin sample 16 can be substantially destroyed by the application of the reducing agent.
- a swelling substance 14 which may not destroy the structure of a keratin sample 16 after application.
- Figure 3 shows the use of a specific swelling substance 14, for a given mode of operation in -association with a plurality of different keratin samples 16 to yield a derived chemical substance 18.
- the plurality of different keratin samples 16 can be taken from a plurality of different mammalian species. Alternatively or additionally, the plurality of different keratin samples 16 can be taken from subjects 11 who are suspected to have a plurality of different pathological states .
- the variations in swelling substances as disclosed in Figure 2 and the variations in keratin samples 16 as disclosed in Figure 3 can be used to identify a particular capability in a particular swelling substance 14 or a particular susceptibility in a given keratin sample 16. For example if a given swelling substance 14 such as formic acid was known to remove an abnormal component from a keratin sample 16 during a particular concentration range and a particular sub-range of the concentration was shown to yield a significantly improved result then a new availability in the formic acid could exist.
- a given swelling substance 14 such as formic acid was known to remove an abnormal component from a keratin sample 16 during a particular concentration range and a particular sub-range of the concentration was shown to yield a significantly improved result then a new availability in the formic acid could exist.
- a particular susceptibility will occur if a keratin sample 16 is known to yield a conclusive result in association with a given mode of operation and a given swelling substance 14 that leads to an improvement in specificity or sensitivity of a diagnostic test to look for the presence of the abnormal component.
- Figure 3 can include a keratin sample 16 taken from a subject 11 who is suspected of having a pathological state which can include one or more cancers or pathological states such as lung cancer, Creutzfeldt-Jacob disease, mad cow disease, infection (bacterial, viral, or a Prion or more generally by other agents), a metabolic disorder (which can include diabetes) , or alternatively hepatitis, heart disease or liver dysfunction.
- a pathological state which can include one or more cancers or pathological states such as lung cancer, Creutzfeldt-Jacob disease, mad cow disease, infection (bacterial, viral, or a Prion or more generally by other agents), a metabolic disorder (which can include diabetes) , or alternatively hepatitis, heart disease or liver dysfunction.
- the keratin sample 16 can include Keratin Type I and Keratin Type II.
- Figure 4 shows an embodiment of the method for detecting the presence of a pathological state in which a given swelling substance 14 and a given keratin sample 16 are used in association with a plurality of different types of methods of comparison between the data 22 and a second group of data 24 contained in the reference database 25 so as to produce an improvement in specificity or sensitivity of the method of analyzing the keratin sample 16.
- An advantage of the present embodiment is that if the abnormal component is present in the derived chemical substance 18 then the derived chemical substance 18 can be further analyzed for the purpose of identifying the nature of the abnormal component so as to provide a health care practitioner with more information about the pathological state. If the abnormal component is a trace metal then atomic absorption spectroscopy or ICP-mass spectrometry could be applied to the derived chemical substance 18 to confirm the nature of the abnormal component.
- the abnormal component in the derived chemical substance 18 is a protein, a carbohydrate, a fatty acid or more generally of organic origin and an antibody can be raised against the abnormal component then a plurality of different techniques such as Western blot analysis, ELISA or cell agglutination assays can be used in an attempt to characterize the abnormal component. In certain instances, immuno-electron microscopy can be used in an attempt to identify the abnormal component in the keratin sample 16 without the need for the use of the derived chemical substance 18 to subsequently be obtained. If the abnormal component is associated with genetic material (being hereditary in narure or acquired by way of a viral vector) then an amplification technique could be applied to determine the sequence and conformation of the abnormal component . In use
- Figure 5 shows an embodiment of the present invention in use.
- a keratin sample 16 can be collected from a subject at a pharmacy 26 .
- the keratin sample 16 can then be sent to a testing laboratory 34 so as to perform the method for detecting the presence of an abnormal component in the keratin sample 16 as seen in Figure 1.
- test kit 28 can be obtained so as to use the test kit 28 embodying the method of detection at the subject's home 30, in association with consultation of the subject's health care practitioner located at a health care clinic 32.
- the subject 11 can visit his or her health care clinic 32 so as to provide the keratin sample 16.
- the health care clinic 32 can perform the method of analyzing the keratin sample 16 themselves or in a further, preferred embodiment. ⁇ .he health care clinic 32 can obtain the keratin sample 16 from the subject 11 so as to forward the keratin sample 16 to the testing laboratory 34.
- This methodology was applied to several hair fibers from individuals of known pathology to determine if the ring observed by Synchrotron Small Angle X-Ray Scatter (SAXS) of hair, specific for the presence of breast cancer, could be removed by such treatment.
- Hair fibers from subjects with breast cancer were immersed in an 85% (v/v) solution of formic acid or in glacial acetic acid for 3 minutes at room temperature. The acid was then decanted and replaced with several changes of Milli-Q water. The fibers were allowed to dry then mounted into a sample holder for exposure to an X-ray source. SAXS image data was collected for these hairs .
- Hair fibers that were taken from the same individual and subsequently treated with formic and acetic acid showed either significant reduction or complete removal of the ring in the zone of interest in the SAXS image.
- Figure 6A is a SAXS image of a hair from an individual with breast cancer.
- Figures 6B and 6C are SAXS images of hair fibers from the same individual post treatment with acetic acid and formic acid respectively. It can be seen from these images that the ring in the zone of interest is significantly diminished after treatment with either acid and hence such treatments may be used as a tool to investigate the underlying change in the fiber associated with the presence of breast cancer.
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009516820A JP2009541747A (en) | 2006-06-29 | 2007-06-27 | Improved method |
AU2007264394A AU2007264394B2 (en) | 2006-06-29 | 2007-06-27 | Improved process |
BRPI0713885-7A BRPI0713885A2 (en) | 2006-06-29 | 2007-06-27 | improved process |
ES07719118T ES2371368T3 (en) | 2006-06-29 | 2007-06-27 | DETECTION OF AN ABNORMAL CHANGE IN THE COMPONENT OF A SAMPLE OF HAIR IN SUBJECTS WHO SUFFER BREAST CANCER. |
CA002652955A CA2652955A1 (en) | 2006-06-29 | 2007-06-27 | Improved process |
AT07719118T ATE520345T1 (en) | 2006-06-29 | 2007-06-27 | DETECTION OF AN ABNORMAL CHANGE IN THE COMPONENT OF A HAIR SAMPLE FROM BREAST CANCER PATIENTS |
EP07719118A EP2032031B1 (en) | 2006-06-29 | 2007-06-27 | Detection of an abnormal change in the component of a hair sample in subjects suffering from breast cancer |
KR1020097001887A KR101087576B1 (en) | 2006-06-29 | 2007-06-27 | Improved process |
US12/306,134 US20090325303A1 (en) | 2006-06-29 | 2007-06-27 | Process |
CNA2007800243800A CN101478916A (en) | 2006-06-29 | 2007-06-27 | Improved process |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2006903508A AU2006903508A0 (en) | 2006-06-29 | Improved Process | |
AU2006903508 | 2006-06-29 | ||
AU2007900272A AU2007900272A0 (en) | 2007-01-19 | Improved Process | |
AU2007900272 | 2007-01-19 | ||
AU2007900308 | 2007-01-22 | ||
AU2007900308A AU2007900308A0 (en) | 2007-01-22 | Improved Process |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008000020A1 true WO2008000020A1 (en) | 2008-01-03 |
Family
ID=38845029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/AU2007/000879 WO2008000020A1 (en) | 2006-06-29 | 2007-06-27 | Improved process |
Country Status (13)
Country | Link |
---|---|
US (1) | US20090325303A1 (en) |
EP (1) | EP2032031B1 (en) |
JP (1) | JP2009541747A (en) |
KR (1) | KR101087576B1 (en) |
CN (1) | CN101478916A (en) |
AR (1) | AR061732A1 (en) |
AT (1) | ATE520345T1 (en) |
AU (1) | AU2007264394B2 (en) |
BR (1) | BRPI0713885A2 (en) |
CA (1) | CA2652955A1 (en) |
ES (1) | ES2371368T3 (en) |
TW (1) | TW200801513A (en) |
WO (1) | WO2008000020A1 (en) |
Cited By (264)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009043115A1 (en) * | 2007-10-04 | 2009-04-09 | Fermiscan Australia Pty Limited | Method for identifying biomarkers which are diagnostic for a pathological condition |
WO2009135902A2 (en) | 2008-05-07 | 2009-11-12 | Vestas Wind Systems A/S | A sectional blade |
WO2011000020A1 (en) * | 2009-06-12 | 2011-01-06 | Sbc Research Pty Ltd | Enhanced method of detection |
WO2011067465A1 (en) | 2009-12-04 | 2011-06-09 | Kristiina Rajala | Formulations and methods for culturing stem cells |
WO2011104644A1 (en) | 2010-02-24 | 2011-09-01 | Koninklijke Philips Electronics N.V. | Hid lighting system |
WO2011104713A1 (en) | 2010-02-25 | 2011-09-01 | Nova Measuring Instruments Ltd. | Method and system for measurng in patterned structures |
WO2011116811A1 (en) | 2010-03-24 | 2011-09-29 | Telefonaktiebolaget Lm Ericsson (Publ) | A node with an improved back up protocol |
WO2012043067A1 (en) | 2010-09-27 | 2012-04-05 | 日本電気株式会社 | Vehicle-mounted device and congestion control method |
WO2012043801A1 (en) | 2010-09-30 | 2012-04-05 | 積水メディカル株式会社 | Patch |
EP2440937A1 (en) * | 2009-06-12 | 2012-04-18 | SBC Research Pty Ltd | A diagnostic method |
WO2012070099A1 (en) | 2010-11-22 | 2012-05-31 | 東芝三菱電機産業システム株式会社 | Rolling mill control device |
US8437570B2 (en) | 2008-05-23 | 2013-05-07 | Microsoft Corporation | Geodesic image and video processing |
US8435428B2 (en) | 2007-02-21 | 2013-05-07 | Air Liquide Electronics U.S. Lp | Methods for forming a ruthenium-based film on a substrate |
US8436015B2 (en) | 2008-09-15 | 2013-05-07 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
US8437858B2 (en) | 2008-03-18 | 2013-05-07 | Imi Intelligent Medical Implants, Ag | Visual prosthesis system for displaying video image and text data |
US8436491B2 (en) | 2009-11-30 | 2013-05-07 | Broadcom Corporation | Low pin count wireless power IC |
US8436175B2 (en) | 2010-03-22 | 2013-05-07 | Rensselaer Polytechnic Institute | Carboxamide bioisosteres of opiates |
US8437177B2 (en) | 2011-01-20 | 2013-05-07 | Panasonic Corporation | Nonvolatile latch circuit and nonvolatile flip-flop circuit |
US8435648B2 (en) * | 2008-12-30 | 2013-05-07 | Cheil Industries, Inc. | Pyridinylene ring compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode |
US8437394B2 (en) | 2008-09-25 | 2013-05-07 | Mediatek Inc. | Adaptive filter |
US8437308B2 (en) | 2009-11-05 | 2013-05-07 | Telefonaktiebolaget L M Ericsson (Publ) | Handover measurements in a mobile communication system |
US8435107B2 (en) | 2005-07-06 | 2013-05-07 | Wms Gaming Inc. | Wagering game system with networked gaming devices |
US8436944B2 (en) | 2009-10-01 | 2013-05-07 | Panasonic Corporation | Wireless communications system, adaptor apparatus for video apparatus, video apparatus and control method for wireless communications system |
US8435961B2 (en) | 2009-06-26 | 2013-05-07 | Massachusetts Institute Of Technology | Methods and compositions for increasing the activity of inhibitory RNA |
US8434718B2 (en) | 2009-09-02 | 2013-05-07 | Eurocopter | Reusable rotorcraft bumper, and a rotorcraft having such a bumper |
US8436334B2 (en) | 2007-10-12 | 2013-05-07 | Agency For Science, Technology And Research | Fabrication of phosphor free red and white nitride-based LEDs |
US8434719B2 (en) | 2008-03-13 | 2013-05-07 | Patria Acostructures Oy | Leading edge element of aircraft, method for manufacturing one, wing and stabilizer |
US8435766B2 (en) | 2009-03-19 | 2013-05-07 | N.V. Desmet Ballestra Engineering S.A. | Enzymatic oil recuperation process |
US8435995B2 (en) | 2009-02-05 | 2013-05-07 | Takeda Pharmaceutical Company Limited | Pyridazinone compounds |
US8435987B2 (en) | 2007-05-07 | 2013-05-07 | Amgen Inc. | Pyrazolo-pyridinone and pyrazolo-pyrazinone compounds as P38 modulators and methods of use thereof |
US8436791B2 (en) * | 2009-01-26 | 2013-05-07 | Seiko Epson Corporation | Light-emitting device and mobility compensating method for driving the same, and electronic device |
US8436762B2 (en) | 2008-01-31 | 2013-05-07 | Bae Systems Information And Electronic Systems Integration Inc. | Determining at least one coordinate of an object using intersecting surfaces |
US8437083B2 (en) | 2009-05-21 | 2013-05-07 | Canon Kabushiki Kaisha | Optical element, optical system including the optical element, and optical apparatus including the optical system |
US8436413B2 (en) | 2008-10-15 | 2013-05-07 | Indian Institute Of Technology, Bombay | Nonvolatile floating gate analog memory cell |
US8436270B2 (en) | 2008-12-22 | 2013-05-07 | Hypertherm, Inc. | Method and apparatus for cutting high quality internal features and contours |
US8435207B2 (en) | 2006-11-06 | 2013-05-07 | Aardvark Medical, Inc. | Irrigation and aspiration devices and methods |
US8435409B2 (en) | 2010-05-28 | 2013-05-07 | Ecolab Usa Inc. | Activated sludge process in wastewater treatment |
US8435560B2 (en) | 2006-12-28 | 2013-05-07 | Dow Corning Corporation | Polynuclear microcapsules |
US8437963B2 (en) | 2008-02-08 | 2013-05-07 | Annica Önell | Method, computer program product and system for enabling clinical decision support |
US8436875B2 (en) | 2008-11-13 | 2013-05-07 | Sharp Kabushiki Kaisha | Display device |
US8436054B2 (en) | 2008-12-23 | 2013-05-07 | E I Du Pont De Nemours And Company | Fluorinated ionomer produced by aqueous polymerization using dispersed particulate of fluorinated ionomer produced in situ |
US8436200B2 (en) | 2008-11-18 | 2013-05-07 | Takeda Pharmaceutical Company Limited | Process for making (R)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-flouro-4- iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione and intermediates thereof |
US8437773B2 (en) | 2009-12-09 | 2013-05-07 | Qualcomm Incorporated | Hierarchical information dissemination for location based systems |
US8437286B2 (en) | 2007-02-22 | 2013-05-07 | Zte (Usa) Inc. | Signaling for multi-hop relay in wireless communication systems |
US8437228B2 (en) | 2008-08-06 | 2013-05-07 | Hitachi, Ltd. | Thermally-assisted magnetic recording head |
US8435960B2 (en) | 1998-12-30 | 2013-05-07 | Lakewood-Amedex, Inc. | Devices for improved wound management |
US8436820B2 (en) | 2008-12-04 | 2013-05-07 | Electronics And Telecommunications Research Institute | Touchpad using resistive electro-conductive fiber and input device having the same |
US8434703B2 (en) | 2008-02-15 | 2013-05-07 | E2V Technologies (Uk) Limited | Apparatus and method for comminution of mineral ore |
US8435540B2 (en) | 2005-04-06 | 2013-05-07 | Ibc Pharmaceuticals, Inc. | Dimeric alpha interferon PEGylated site-specifically shows enhanced and prolonged efficacy in VIVO |
US8434372B2 (en) | 2008-09-12 | 2013-05-07 | Fras Technology As | Fluid analysis system and method for operation of an analysis system |
US8438479B2 (en) | 2008-11-25 | 2013-05-07 | Panasonic Corporation | Operation support apparatus and method of the same |
US8437224B2 (en) * | 2006-08-03 | 2013-05-07 | Wfs Technologies Ltd. | Underwater communications |
US8435476B2 (en) | 2006-08-03 | 2013-05-07 | Spawnt Private S.A.R.L. | Process for supplying a fuel cell with hydrogen by means of silanes or polysilanes |
US8436134B2 (en) | 2008-07-18 | 2013-05-07 | University Of Chicago | Semiconducting polymers |
US8437114B2 (en) | 2008-11-26 | 2013-05-07 | Murata Manufacturing Co., Ltd. | ESD Protection Device |
US8435275B2 (en) | 2011-03-30 | 2013-05-07 | Valkee Oy | Portable ear light device |
US8434242B2 (en) | 2010-09-16 | 2013-05-07 | Velico Medical, Inc. | Spray dried human plasma |
US8434183B2 (en) | 2010-08-13 | 2013-05-07 | Braun Gmbh | Brush section for an electric toothbrush |
US8436312B2 (en) * | 2008-10-08 | 2013-05-07 | National Institute Of Radiological Sciences | DOI type radiation detector |
US8437069B2 (en) | 2008-03-11 | 2013-05-07 | Sipix Imaging, Inc. | Luminance enhancement structure for reflective display devices |
US8435928B2 (en) | 2007-07-13 | 2013-05-07 | Ishihara Sangyo Kaisha, Ltd. | Herbicidal composition |
US8437827B2 (en) | 2009-06-30 | 2013-05-07 | Abbott Diabetes Care Inc. | Extruded analyte sensors and methods of using same |
US8435513B2 (en) | 2008-07-08 | 2013-05-07 | Oncomed Pharmaceuticals, Inc. | NOTCH1 receptor antibodies and methods of treatment |
US8435914B2 (en) | 2009-05-14 | 2013-05-07 | Univation Technologies, Llc | Mixed metal catalyst systems having a tailored hydrogen response |
US8436060B2 (en) | 2010-03-30 | 2013-05-07 | Samsung Electronics Co., Ltd. | Organic aerogel and composition for the organic aerogel |
US8436918B2 (en) | 2009-02-27 | 2013-05-07 | Deluxe Laboratories, Inc. | Systems, apparatus and methods for subtitling for stereoscopic content |
US8438600B2 (en) | 2009-08-20 | 2013-05-07 | Lg Electronics Inc. | Method of processing EPG metadata in network device and network device for controlling the same |
US8435246B2 (en) | 2009-11-02 | 2013-05-07 | Synvasive Technology, Inc. | Knee arthroplasty apparatus and method |
US8438616B2 (en) | 2008-09-28 | 2013-05-07 | Huawei Technologies Co., Ltd. | Method for terminal configuration and management and terminal device |
US8436092B2 (en) | 2009-01-16 | 2013-05-07 | Tsinghua University | Giant magnetoresistance composite material containing carbon nanotubes |
US8435454B2 (en) | 2009-07-09 | 2013-05-07 | Siemens Medical Solutions Usa, Inc. | Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure |
US8438272B2 (en) | 2010-08-31 | 2013-05-07 | Sap Ag | Methods and systems for managing quality of services for network participants in a networked business process |
US8435970B2 (en) | 2006-06-29 | 2013-05-07 | Astex Therapeutics Limited | Pharmaceutical combinations of 1-cyclopropyl-3-[3-(5-morpholin-4-ylmethyl-1H-benzoimidazol-2-yl)-1H-pyrazol-4-yl]-urea |
US8436383B2 (en) * | 2010-02-17 | 2013-05-07 | Lg Innotek Co., Ltd. | Light emitting device, light emitting device package, and lighting system |
US8434488B2 (en) | 2009-06-08 | 2013-05-07 | Covidien Lp | Endotracheal tube with dedicated evacuation port |
US8435749B2 (en) | 2008-06-30 | 2013-05-07 | Oncotherapy Science, Inc. | Anti-CDH3 antibodies labeled with radioisotope label and uses thereof |
US8438020B2 (en) | 2007-10-12 | 2013-05-07 | Panasonic Corporation | Vector quantization apparatus, vector dequantization apparatus, and the methods |
US8437597B2 (en) | 2009-06-19 | 2013-05-07 | Corning Cable Systems Llc | Mounting of fiber optic cable assemblies within fiber optic shelf assemblies |
US8435997B2 (en) | 2007-08-10 | 2013-05-07 | Marquette University | Cysteine prodrugs to treat schizophrenia and drug addiction |
US8435770B2 (en) | 2007-05-09 | 2013-05-07 | Mascoma Corporation | Gene knockout mesophilic and thermophilic organisms, and methods of use thereof |
US8434344B2 (en) * | 2007-12-12 | 2013-05-07 | Service Solutions U.S. Llc | Verification of scale calibration method and apparatus |
US8435993B2 (en) | 2010-12-07 | 2013-05-07 | Philadelphia Health And Education Corporation | Methods of inhibiting metastasis from cancer |
US8436028B2 (en) | 2007-06-20 | 2013-05-07 | Merck Sharp & Dohme Corp | CETP inhibitors derived from benzoxazole arylamides |
US8435828B2 (en) | 2010-01-13 | 2013-05-07 | Renesas Electronics Corporation | Method of manufacturing semiconductor device |
US8434872B2 (en) | 2007-07-30 | 2013-05-07 | National Institute Of Information And Communications Technology | Multi-viewpoint floating image display device |
US8435785B2 (en) | 2005-06-01 | 2013-05-07 | Wisconsin Alumni Research Foundation | Method of forming dendritic cells from embryonic stem cells |
US8436053B2 (en) | 2008-12-23 | 2013-05-07 | E.I. Du Pont De Nemours And Company | Fluorinated ionomer produced by aqueous polymerization using dispersed particulate of fluorinated ionomer |
US8437845B2 (en) | 2007-02-01 | 2013-05-07 | Ls Biopath, Inc. | Electrical methods for detection and characterization of abnormal tissue and cells |
US8438044B2 (en) | 2011-01-18 | 2013-05-07 | Audiahealth, Llc | Systems and methods combining print and audio technologies to deliver and personalize health information |
US8435978B2 (en) * | 2006-09-29 | 2013-05-07 | Gruenenthal Gmbh | Substituted sulfonamide compounds |
US8436444B2 (en) * | 2008-12-10 | 2013-05-07 | Si-Nano Inc. | Thin film photoelectric conversion device and method for manufacturing thin film photoelectric conversion device |
US8435768B2 (en) | 2009-01-30 | 2013-05-07 | Ajinomoto Co., Inc. | Method for producing succinic acid using a yeast belonging to the genus Yarrowia |
US8436078B2 (en) * | 2008-04-28 | 2013-05-07 | Kuraray Noritake Dental Inc. | Dental composition and composite resin |
US8436011B2 (en) | 2008-07-08 | 2013-05-07 | Sanofi | Pyridinopyridinone derivatives, preparation thereof and therapeutic use thereof |
US8436158B2 (en) | 2008-06-18 | 2013-05-07 | Pfizer Inc. | Antibodies to IL-6 and their uses |
US8435988B2 (en) | 2010-10-06 | 2013-05-07 | Glaxosmithkline Llc | Benzimidazole derivatives as P13 kinase inhibitors |
US8436546B2 (en) | 2006-10-20 | 2013-05-07 | Luxim Corporation | Electrodeless lamps and methods |
US8438452B2 (en) | 2008-12-29 | 2013-05-07 | Intel Corporation | Poison bit error checking code scheme |
US8435742B2 (en) | 2007-11-01 | 2013-05-07 | Yamaguchi University | Method and kit for detection/quantification of target RNA |
US8434659B2 (en) * | 2008-10-14 | 2013-05-07 | Hesse & Knipps Gmbh | Bonding device, ultrasonic transducer, and bonding method |
US8435289B2 (en) | 2005-02-11 | 2013-05-07 | Abbott Medical Optics Inc. | Rapid exchange IOL insertion apparatus and methods of using |
US8437247B2 (en) | 2008-10-31 | 2013-05-07 | Htc Corporation | Methods of packet element transmission in wireless communications system |
US8436862B2 (en) | 2008-12-11 | 2013-05-07 | Nvidia Corporation | Method and system for enabling managed code-based application program to access graphics processing unit |
US8434972B2 (en) | 2007-02-17 | 2013-05-07 | Hartmetall-Werkzeugfabrik Paul Horn Gmbh | Broaching tool, in particular keyway broaching tool |
US8435986B2 (en) | 2008-08-14 | 2013-05-07 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Bicyclic traizole derivatives for treating of tumors |
US8435272B2 (en) | 2009-04-09 | 2013-05-07 | Arthrex, Inc. | Clavicle nail with locking end cap |
US8435341B2 (en) | 2009-11-03 | 2013-05-07 | Agfa-Gevaert N.V. | Preparing and dispersing surface-modified colour pigments |
US8437594B2 (en) | 2010-03-16 | 2013-05-07 | Furukawa Electric Co., Ltd. | Holey fiber |
US8434893B2 (en) | 2007-10-17 | 2013-05-07 | Lsi Industries, Inc. | Luminaire and methods of use |
US8434605B2 (en) | 2008-06-06 | 2013-05-07 | Nsk-Warner K.K. | One-way clutch of roller type for starter of motor bike |
US8435552B2 (en) | 2007-02-09 | 2013-05-07 | Royal College Of Surgeons In Ireland | Collagen/hydroxyapatite composite scaffold, and process for the production thereof |
US8435769B2 (en) | 2007-04-13 | 2013-05-07 | Monsanto Technology Llc | Use of glyphosate to produce shikimic acid in microorganisms |
US8437173B2 (en) | 2010-03-19 | 2013-05-07 | Panasonic Corporation | Nonvolatile memory element, manufacturing method thereof, design support method therefor, and nonvolatile memory device |
US8437057B2 (en) | 2007-05-16 | 2013-05-07 | Seereal Technologies S.A. | Method for rendering and generating color video holograms in real time |
US8435636B2 (en) | 2007-03-29 | 2013-05-07 | Akron Polymer Systems, Inc. | Optical compensation films of brominated styrenic polymers and related methods |
US8435383B2 (en) | 2006-08-25 | 2013-05-07 | Edwin X Graf | Process and machine for making air dried tissue |
US8437357B2 (en) | 2007-05-29 | 2013-05-07 | Packetfront Network Products Ab | Method of connecting VLAN systems to other networks via a router |
US8434647B2 (en) | 2009-08-08 | 2013-05-07 | Riad Aamar | Device for measuring and dispensing a prescribed amount of liquid |
US8436157B2 (en) | 2008-03-26 | 2013-05-07 | Tate & Lyle Technology Limited | Method for the production of sucralose |
US8435276B2 (en) | 2006-02-27 | 2013-05-07 | Thomas Perez | Method and apparatus for the combined application of light therapy, optic diagnosis, and fluid to tissue |
US8434311B2 (en) | 2006-11-01 | 2013-05-07 | Alstom Technology Ltd. | System for controlling a combustion process for a gas turbine |
US8437951B2 (en) | 2009-09-14 | 2013-05-07 | Research In Motion Limited | Methods, device and systems for determining route metrics using stored route information |
US8435751B2 (en) | 2008-09-25 | 2013-05-07 | Gambro Lundia Ab | Membrane for cell expansion |
US8435968B2 (en) | 2008-09-19 | 2013-05-07 | Pimco 2664 Limited | Aryl-phenyl-sulfonamido-cycloalkyl compounds and their use |
US8436754B2 (en) | 2009-03-27 | 2013-05-07 | Huawei Technologies Co., Ltd. | Encoding and decoding method and device |
US8436069B2 (en) | 2009-03-30 | 2013-05-07 | Fujifilm Corporation | Ink composition |
US8435064B2 (en) | 2009-02-12 | 2013-05-07 | Fronius International Gmbh | Mounting for a DC-AC converter and method for fitting a DC-AC converter |
US8435539B2 (en) | 2004-02-13 | 2013-05-07 | Immunomedics, Inc. | Delivery system for cytotoxic drugs by bispecific antibody pretargeting |
US8435745B2 (en) | 2005-02-14 | 2013-05-07 | Zymogenetics, Inc. | Methods of using IL-31 antagonists in diseases mediated by cutaneous lymphocyte antigen positive T cells |
US8436185B2 (en) | 2008-01-08 | 2013-05-07 | Merck Sharp & Dohme Corp. | Pharmaceutically acceptable salts of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide |
US8435209B2 (en) | 2009-12-30 | 2013-05-07 | Medtronic Minimed, Inc. | Connection and alignment detection systems and methods |
US8435459B2 (en) | 2003-01-07 | 2013-05-07 | Micropyretics Heaters International, Inc. | Heating and sterilizing apparatus and method of using same |
US8437792B2 (en) | 2007-02-14 | 2013-05-07 | Qualcomm Incorporated | Uplink power control for LTE |
US8436698B2 (en) | 2009-11-02 | 2013-05-07 | Harris Corporation | MEMS-based tunable filter |
US8438231B2 (en) | 2010-01-08 | 2013-05-07 | Alcatel Lucent | Telecommunication messaging through a social networking service |
US8435545B2 (en) * | 2011-09-01 | 2013-05-07 | Qualicaps, Inc. | Capsule having broad color spectrum |
US8434323B2 (en) | 2008-07-14 | 2013-05-07 | Johnson Controls Technology Company | Motor cooling applications |
US8435555B2 (en) | 2008-05-01 | 2013-05-07 | Eminate Limited | Salt product |
US8437418B2 (en) | 2008-04-30 | 2013-05-07 | Huawei Technologies Co., Ltd. | Method and apparatus for detecting signals of multi-input multi-output system |
US8435524B2 (en) | 2008-07-16 | 2013-05-07 | Institute For Research In Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
US8436342B2 (en) | 2009-01-12 | 2013-05-07 | Samsung Display Co., Ltd. | Organic light emitting display device and method of manufacturing the same |
US8437997B2 (en) | 2008-01-22 | 2013-05-07 | Exxonmobil Upstream Research Company | Dynamic connectivity analysis |
US8434308B2 (en) | 2009-09-15 | 2013-05-07 | General Electric Company | Heat pipes for transferring heat to an organic rankine cycle evaporator |
US8435402B2 (en) * | 2010-03-29 | 2013-05-07 | Marathon Canadian Oil Sands Holding Limited | Nozzle reactor and method of use |
US8435976B2 (en) | 2009-09-08 | 2013-05-07 | F. Hoffmann-La Roche | 4-substituted pyridin-3-yl-carboxamide compounds and methods of use |
US8436156B2 (en) | 2008-01-04 | 2013-05-07 | Tate & Lyle Technology Limited | Method for the production of sucralose |
US8435939B2 (en) | 2000-09-05 | 2013-05-07 | Biokine Therapeutics Ltd. | Polypeptide anti-HIV agent containing the same |
US8436614B2 (en) | 2008-12-17 | 2013-05-07 | Siemens Aktiengesellschaft | Local coil arrangement for magnetic resonance applications with activatable marker |
US8434524B2 (en) | 2011-01-31 | 2013-05-07 | Vanderbilt University | Elastic hydraulic accumulator/reservoir system |
US8435761B2 (en) | 2006-06-29 | 2013-05-07 | Ucb Pharma Sa | DNA encoding antibody molecules which bind human IL-17 |
US8437964B2 (en) | 2005-12-19 | 2013-05-07 | Analiza, Inc. | Systems and methods involving data patterns such as spectral biomarkers |
US8436833B2 (en) | 2009-11-25 | 2013-05-07 | Corning Incorporated | Methods and apparatus for sensing touch events on a display |
US8435980B2 (en) | 2009-07-15 | 2013-05-07 | Abbvie Inc. | Pyrrolopyridine inhibitors of kinases |
US8435446B2 (en) | 2007-07-25 | 2013-05-07 | Alcoa Inc. | Surfaces and coatings for the removal of carbon dioxide |
US8436008B2 (en) | 2008-12-22 | 2013-05-07 | Incyte Corporation | Substituted heterocyclic compounds |
US8435228B2 (en) | 2009-08-12 | 2013-05-07 | Medrad, Inc. | Interventional catheter assemblies incorporating guide wire brake and management systems |
US8436235B2 (en) | 2001-11-13 | 2013-05-07 | U.S. Smokeless Tobacco Company | Cloning of cytochrome p450 genes from Nicotiana |
US8434716B2 (en) | 2006-01-19 | 2013-05-07 | The Boeing Company | Compliant crown panel for an aircraft |
US8434781B2 (en) | 2009-04-16 | 2013-05-07 | Doona Holdings Ltd | Baby safety car seat convertible into a rollable baby seat |
US8436488B2 (en) * | 2009-03-03 | 2013-05-07 | Bluewater Energy Services B.V. | Semi-direct variable speed drive with N+1 power availability |
US8434889B2 (en) | 2010-03-19 | 2013-05-07 | GE Lighting Solutions, LLC | Lighted display case having reduced glare |
US8435775B2 (en) | 2006-09-06 | 2013-05-07 | Medical Research Council | Mutant Pfu DNA polymerase |
US8436002B2 (en) | 2009-10-23 | 2013-05-07 | Eli Lilly And Company | AKT inhibitors |
US8434383B2 (en) | 2009-12-04 | 2013-05-07 | Hyundai Motor Company | Transmission shifting apparatus for vehicle |
US8437962B2 (en) | 2009-11-25 | 2013-05-07 | Halliburton Energy Services, Inc. | Generating probabilistic information on subterranean fractures |
US8435319B2 (en) | 2007-12-07 | 2013-05-07 | Cedric Dackam | Filter unit for the filtration of gaseous fluids, in particular air filter in internal combustion engines |
US8436024B2 (en) | 2009-10-02 | 2013-05-07 | Astrazeneca Ab | 2-pyridone compounds |
US8436537B2 (en) | 2008-07-07 | 2013-05-07 | Samsung Sdi Co., Ltd. | Substrate structure for plasma display panel, method of manufacturing the substrate structure, and plasma display panel including the substrate structure |
US8436149B2 (en) | 2006-10-27 | 2013-05-07 | Abbvie Biotechnology Ltd | Crystalline anti-hTNFalpha antibodies |
US8434913B2 (en) | 2008-05-30 | 2013-05-07 | Koninklijke Philips Electronics N.V. | Round illumination device |
US8437857B2 (en) | 2008-09-04 | 2013-05-07 | Boston Scientific Neuromodulation Corporation | Multiple tunable central cathodes on a paddle for increased medial-lateral and rostral-caudal flexibility via current steering |
US8435313B2 (en) | 2008-05-19 | 2013-05-07 | Furanix Technologies, B.V. | Fuel composition |
US8436510B2 (en) * | 2008-04-30 | 2013-05-07 | Murata Manufacturing Co., Ltd. | Boundary acoustic wave device |
US8434184B2 (en) | 2010-08-13 | 2013-05-07 | Braun Gmbh | Fracture resistant brush head |
US8434910B2 (en) | 2010-06-01 | 2013-05-07 | Lg Innotek Co., Ltd. | Light emitting device package and lighting system |
US8435984B2 (en) | 2007-02-26 | 2013-05-07 | Achillion Pharmaceuticals, Inc. | Tertiary amine substituted peptides useful as inhibitors of HCV replication |
US8434522B2 (en) | 2007-05-31 | 2013-05-07 | Tokyo Electron Limited | Fluid control apparatus |
US8434195B2 (en) | 2007-04-05 | 2013-05-07 | Siemens Ag Österreich | Door rail and door attachment system for passenger rail cars |
US8435556B2 (en) | 2000-12-22 | 2013-05-07 | Alltranz, Llc | Transdermal delivery of cannabidiol |
US8438210B2 (en) | 2009-05-04 | 2013-05-07 | Comcast Cable Communications, Llc | Sharing media content based on a media server |
US8436172B2 (en) | 2009-08-31 | 2013-05-07 | Udc Ireland Limited | Material selecting method upon purifying iridium complex by sublimation |
US8437183B2 (en) | 2009-12-16 | 2013-05-07 | Sandisk Il Ltd. | Auxiliary parity bits for data written in multi-level cells |
US8434285B2 (en) | 2007-01-19 | 2013-05-07 | Steven L. Harrison | Tiled transition bracketing |
US8437293B2 (en) | 2007-06-19 | 2013-05-07 | Telefonaktiebolaget L M Ericsson (Publ) | Methods and systems for scheduling resources in a telecommunication system |
US8436036B2 (en) | 2009-04-24 | 2013-05-07 | Janssen R&D Ireland | Diaryl ethers |
US8435342B2 (en) | 2009-12-15 | 2013-05-07 | Shell Oil Company | Concrete composition |
US8437970B2 (en) | 2009-06-05 | 2013-05-07 | Apple Inc. | Restoring and storing magnetometer calibration data |
US8435752B2 (en) | 2007-01-18 | 2013-05-07 | University Of Southern California | Gene polymorphisms predictive for dual TKI therapy |
US8435325B2 (en) | 2008-10-23 | 2013-05-07 | Hitachi, Ltd. | Method and device for removing CO2 and H2S |
US8434906B2 (en) | 2010-02-23 | 2013-05-07 | General Electric Company | Lighting system with thermal management system |
US8436925B2 (en) | 2008-12-08 | 2013-05-07 | Sony Corporation | Solid-state imaging device, method for processing signal of solid-state imaging device, and imaging apparatus |
US8435355B2 (en) | 2008-12-29 | 2013-05-07 | Weyerhaeuser Nr Company | Fractionation of lignocellulosic material using ionic liquids |
US8436459B2 (en) | 2008-11-28 | 2013-05-07 | Mitsubishi Electric Corporation | Power semiconductor module |
US8435119B2 (en) | 2007-12-26 | 2013-05-07 | Scientific Games Holdings Limited | User-controlled sweepstakes entries |
US8438021B2 (en) | 2009-10-15 | 2013-05-07 | Huawei Technologies Co., Ltd. | Signal classifying method and apparatus |
US8436182B2 (en) | 2008-05-23 | 2013-05-07 | Zaklady Farmaceutyczne Polpharma Sa | Process for preparation of solifenacin and/or the pharmaceutically acceptable salts thereof of high pharmaceutical purity |
US8436213B2 (en) | 2008-10-10 | 2013-05-07 | Exxonmobil Chemical Patents Inc. | Process for producing phenol and methyl ethyl ketone |
US8437882B2 (en) * | 2010-02-17 | 2013-05-07 | Inscope Energy, Llc | Managing power utilized within a local power network |
US8435792B2 (en) | 2010-01-14 | 2013-05-07 | Baxter International Inc. | Methods and compositions for treating bleeding disorders |
US8437794B2 (en) | 2010-01-28 | 2013-05-07 | Alcatel Lucent | Methods of determining uplink target signal-to-interfence-and-noise ratios and systems thereof |
US8436171B2 (en) | 2008-02-01 | 2013-05-07 | Akinion Pharmaceuticals Ab | Amino substituted pyrazines as inhibitors or protein kinases |
US8434776B2 (en) | 2010-08-16 | 2013-05-07 | Andy WUTHRICH | Bicycle frame with rear suspension system |
US8435002B2 (en) | 2004-08-30 | 2013-05-07 | Lord Corporation | Helicopter vibration control system and rotating assembly rotary forces generators for canceling vibrations |
US8435778B2 (en) | 2010-05-13 | 2013-05-07 | Suntory Holdings Limited | Gene encoding lignan methyltransferase and use thereof |
US8435917B2 (en) | 2008-12-23 | 2013-05-07 | Sued-Chemie Catalysts Italia S.R.L. | Ammonia oxidation catalysts |
US8436110B2 (en) | 2008-10-31 | 2013-05-07 | Dow Global Technologies Llc | Olefin metathesis process employing bimetallic ruthenium complex with bridging hydrido ligands |
US8437806B2 (en) | 2009-03-03 | 2013-05-07 | Lg Electronics Inc. | Mobile terminal and method for displaying data in mobile terminal |
US8437079B2 (en) | 2011-05-06 | 2013-05-07 | Leapers, Inc. | Apparatus including a reticle, assembly and method for operating the same |
US8434422B2 (en) | 2009-04-20 | 2013-05-07 | Dow Global Technologies Llc | Coating apparatus and method |
US8436512B2 (en) | 2010-04-06 | 2013-05-07 | Senseor | Method of rapidly interrogating elastic wave sensors |
US8435999B2 (en) | 2007-08-13 | 2013-05-07 | Monsanto Technology Llc | Compositions and methods for controlling nematodes |
US8436436B2 (en) | 2006-08-01 | 2013-05-07 | Washington University | Multifunctional nanoscopy for imaging cells |
US8436218B2 (en) | 2010-05-27 | 2013-05-07 | Honeywell International Inc. | Azeotrope-like composition of hexafluoropropane, hexafluoropropene and hydrogen fluoride |
US8436005B2 (en) | 2008-04-03 | 2013-05-07 | Abbott Laboratories | Macrocyclic pyrimidine derivatives |
US8434460B2 (en) | 2010-10-29 | 2013-05-07 | Ford Global Technologies, Llc | Integrally molded carbon canister |
US8435486B2 (en) * | 2010-05-24 | 2013-05-07 | Toyota Jidosha Kabushiki Kaisha | Redox material for thermochemical water splitting, and method for producing hydrogen |
US8435721B2 (en) | 2008-02-21 | 2013-05-07 | Nissan Chemical Industries, Ltd. | Resist underlayer film forming composition and forming method of resist pattern using the same |
US8436102B2 (en) | 2009-07-06 | 2013-05-07 | Denki Kagaku Kogyo Kabushiki Kaisha | Polychloroprene latex composition, process for production of same, and products of forming thereof |
US8437527B2 (en) | 2010-06-16 | 2013-05-07 | Hitachi Aloka Medical, Ltd. | Ultrasound diagnostic apparatus |
US8435523B2 (en) | 2009-05-04 | 2013-05-07 | Abbott Research B.V. | Antibodies against nerve growth factor (NGF) with enhanced in vivo stability |
US8436205B2 (en) | 2008-10-23 | 2013-05-07 | Actelion Pharmaceuticals Ltd. | Tetrahydronaphthalene compounds |
US8434877B2 (en) | 2009-08-20 | 2013-05-07 | Canon Kabushiki Kaisha | Illumination optical system and projection display apparatus |
US8436163B2 (en) | 2000-05-04 | 2013-05-07 | Avi Biopharma, Inc. | Splice-region antisense composition and method |
US8435992B2 (en) | 2008-05-16 | 2013-05-07 | Pharma Mar S.A. | Multiple myeloma treatments |
US8437278B2 (en) | 2009-07-02 | 2013-05-07 | Seiko Epson Corporation | Service providing apparatus for digital processing service, wireless communication system, and wireless communication method |
US8437712B2 (en) | 2005-10-27 | 2013-05-07 | Telecom Italia S.P.A. | Method and system for multiple antenna communications using multiple transmission modes, related apparatus and computer program product |
US8434914B2 (en) | 2009-12-11 | 2013-05-07 | Osram Sylvania Inc. | Lens generating a batwing-shaped beam distribution, and method therefor |
US8436755B2 (en) | 2010-05-21 | 2013-05-07 | Research In Motion Limited | Methods and devices for reducing sources in binary entropy coding and decoding |
US8436114B2 (en) | 2010-10-21 | 2013-05-07 | Exxonmobil Chemical Patents Inc. | Polyethylene and process for production thereof |
US8435771B2 (en) | 2008-05-07 | 2013-05-07 | Novozymes A/S | Fermentation of a lignocellulose-containing material |
US8435415B2 (en) | 2009-11-24 | 2013-05-07 | The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology | Nanofabrication process and nanodevice |
US8436090B2 (en) | 2008-09-16 | 2013-05-07 | Nippon Shokubai Co., Ltd. | Production method and method for enhancing liquid permeability of water-absorbing resin |
US8435725B2 (en) | 2007-09-20 | 2013-05-07 | Agfa-Gevaert Nv | Security laminates with interlaminated transparent embossed polymer hologram |
US8434236B2 (en) * | 2007-02-26 | 2013-05-07 | Pellenc (Societe Anonyme) | Chain saw with tension adjustment |
US8436065B2 (en) | 2010-04-01 | 2013-05-07 | Samsung Electronics Co., Ltd. | Aerogel, and composition and method for manufacture of the aerogel |
US8434190B2 (en) | 2008-09-01 | 2013-05-07 | Braun Gmbh | Toothbrush and method of manufacturing it |
US8437798B2 (en) | 2009-04-27 | 2013-05-07 | Motorola Mobility Llc | Uplink scheduling support in multi-carrier wireless communication systems |
US8434581B2 (en) | 2008-12-19 | 2013-05-07 | Zf Friedrichshafen Ag | Suspension device having anti-roll compensation |
US8437332B2 (en) | 2009-06-22 | 2013-05-07 | Qualcomm Incorporated | Low complexity unified control channel processing |
US8436001B2 (en) | 2010-04-07 | 2013-05-07 | F. Hoffmann-La Roche Ag | Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use |
US8435701B2 (en) * | 2007-11-27 | 2013-05-07 | Southbourne Investments Ltd. | Holographic recording medium |
US8435554B2 (en) | 2003-02-21 | 2013-05-07 | Shin Nippon Biomedical Laboratories, Ltd. | Compositons for nasal administration of pharmaceuticals |
US8436295B2 (en) | 2009-09-15 | 2013-05-07 | Canon Anelva Corporation | Device for measuring mean free path, vacuum gauge, and method for measuring mean free path |
US8436137B2 (en) | 2008-12-03 | 2013-05-07 | Koji Kawakami | Selective anticancer chimeric peptide comprising an EGF receptor-binding peptide and a cytotoxic peptide |
US8434286B2 (en) | 2010-03-03 | 2013-05-07 | Yuyama Manufacturing Co., Ltd. | Medicament dispensing machine |
US8437067B2 (en) | 2008-03-18 | 2013-05-07 | Konica Minolta Holdings, Inc. | Electrochemical display element |
US8436035B2 (en) | 2006-12-18 | 2013-05-07 | Novartis Ag | Organic compounds |
US8435056B2 (en) | 2009-04-16 | 2013-05-07 | Enphase Energy, Inc. | Apparatus for coupling power generated by a photovoltaic module to an output |
US8436012B2 (en) | 2008-08-05 | 2013-05-07 | Daiichi Sankyo Company, Limited | Imidazopyridin-2-one derivatives |
EP2617794A2 (en) | 2008-05-07 | 2013-07-24 | E. I. du Pont de Nemours and Company | Compositions comprising 2,3,3,3- tetrafluoropropene |
EP2623491A2 (en) | 2009-04-02 | 2013-08-07 | Merck Patent GmbH | Piperidine and piperazine derivatives as autotaxin inhibitors |
WO2013124832A2 (en) | 2012-02-24 | 2013-08-29 | Ranbaxy Laboratories Limited | Stabilized controlled-release pharmaceutical composition comprising gliclazide |
WO2013128380A1 (en) | 2012-02-28 | 2013-09-06 | Koninklijke Philips N.V. | Device for light based skin treatment |
WO2013128369A1 (en) | 2012-02-28 | 2013-09-06 | Koninklijke Philips N.V. | Aed with compression sensor |
EP2637202A2 (en) | 2007-09-28 | 2013-09-11 | Tessera, Inc. | Flip chip interconnection with etched posts on a microelectronic element joined to etched posts on a substrate by a fusible metal and corresponding manufacturing method |
WO2013132448A1 (en) | 2012-03-07 | 2013-09-12 | Kba-Notasys Sa | Method of checking producibility of a composite security design of a security document on a line of production equipment and digital computer environment for implementing the same |
WO2013156630A1 (en) | 2012-04-20 | 2013-10-24 | Alphaptose Gmbh | S-enantiomer of a tri-substituted glycerol compound |
EP2796818A1 (en) | 2013-04-22 | 2014-10-29 | Shell Internationale Research Maatschappij B.V. | Method and apparatus for producing a liquefied hydrocarbon stream |
EP2796145A1 (en) | 2013-04-22 | 2014-10-29 | CSL Behring GmbH | Complex |
US9030001B2 (en) | 2010-07-27 | 2015-05-12 | Tessera, Inc. | Microelectronic packages with nanoparticle joining |
US9496236B2 (en) | 2010-12-10 | 2016-11-15 | Tessera, Inc. | Interconnect structure |
US9633971B2 (en) | 2015-07-10 | 2017-04-25 | Invensas Corporation | Structures and methods for low temperature bonding using nanoparticles |
WO2019186577A1 (en) | 2018-03-27 | 2019-10-03 | Council Of Scientific And Industrial Research | A non-invasive and remote method to screen cancer |
US10535626B2 (en) | 2015-07-10 | 2020-01-14 | Invensas Corporation | Structures and methods for low temperature bonding using nanoparticles |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20090108605A (en) * | 2007-01-12 | 2009-10-15 | 베로니카 제임스 | Biometric diagnosis |
WO2011119235A1 (en) * | 2010-03-24 | 2011-09-29 | Glendon John Parker | Methods for conducting genetic analysis using protein polymorphism |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000034774A1 (en) * | 1998-12-10 | 2000-06-15 | Fiberscan Pty Ltd | Using hair to screen for breast cancer |
US6350582B1 (en) * | 1987-12-28 | 2002-02-26 | Psychemedics Corporation | Hair analysis method |
WO2003060513A2 (en) * | 2002-01-04 | 2003-07-24 | E2V Technologies Limited | Method and apparatus for cancer detection |
US20060024705A1 (en) * | 2004-06-07 | 2006-02-02 | Wella AG, Board of Regents of the University of Oklahoma and | Molecular analysis of hair follicles for disease |
CN1847846A (en) * | 2005-04-14 | 2006-10-18 | 威尔基因科技股份有限公司 | Hair detecting method for evaluating health status |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL125880A (en) * | 1998-08-21 | 2000-11-21 | Fish Falk | Method for the determination of analyte concentration in blood |
-
2007
- 2007-06-25 TW TW096122855A patent/TW200801513A/en unknown
- 2007-06-27 AU AU2007264394A patent/AU2007264394B2/en not_active Ceased
- 2007-06-27 AT AT07719118T patent/ATE520345T1/en not_active IP Right Cessation
- 2007-06-27 BR BRPI0713885-7A patent/BRPI0713885A2/en not_active Application Discontinuation
- 2007-06-27 CN CNA2007800243800A patent/CN101478916A/en active Pending
- 2007-06-27 KR KR1020097001887A patent/KR101087576B1/en not_active IP Right Cessation
- 2007-06-27 WO PCT/AU2007/000879 patent/WO2008000020A1/en active Application Filing
- 2007-06-27 EP EP07719118A patent/EP2032031B1/en not_active Not-in-force
- 2007-06-27 ES ES07719118T patent/ES2371368T3/en active Active
- 2007-06-27 US US12/306,134 patent/US20090325303A1/en not_active Abandoned
- 2007-06-27 JP JP2009516820A patent/JP2009541747A/en not_active Ceased
- 2007-06-27 CA CA002652955A patent/CA2652955A1/en not_active Abandoned
- 2007-06-28 AR ARP070102902A patent/AR061732A1/en unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6350582B1 (en) * | 1987-12-28 | 2002-02-26 | Psychemedics Corporation | Hair analysis method |
WO2000034774A1 (en) * | 1998-12-10 | 2000-06-15 | Fiberscan Pty Ltd | Using hair to screen for breast cancer |
WO2003060513A2 (en) * | 2002-01-04 | 2003-07-24 | E2V Technologies Limited | Method and apparatus for cancer detection |
US20060024705A1 (en) * | 2004-06-07 | 2006-02-02 | Wella AG, Board of Regents of the University of Oklahoma and | Molecular analysis of hair follicles for disease |
CN1847846A (en) * | 2005-04-14 | 2006-10-18 | 威尔基因科技股份有限公司 | Hair detecting method for evaluating health status |
Non-Patent Citations (5)
Cited By (274)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8435960B2 (en) | 1998-12-30 | 2013-05-07 | Lakewood-Amedex, Inc. | Devices for improved wound management |
US8436163B2 (en) | 2000-05-04 | 2013-05-07 | Avi Biopharma, Inc. | Splice-region antisense composition and method |
US8435939B2 (en) | 2000-09-05 | 2013-05-07 | Biokine Therapeutics Ltd. | Polypeptide anti-HIV agent containing the same |
US8435556B2 (en) | 2000-12-22 | 2013-05-07 | Alltranz, Llc | Transdermal delivery of cannabidiol |
US8436235B2 (en) | 2001-11-13 | 2013-05-07 | U.S. Smokeless Tobacco Company | Cloning of cytochrome p450 genes from Nicotiana |
US8435459B2 (en) | 2003-01-07 | 2013-05-07 | Micropyretics Heaters International, Inc. | Heating and sterilizing apparatus and method of using same |
US8435554B2 (en) | 2003-02-21 | 2013-05-07 | Shin Nippon Biomedical Laboratories, Ltd. | Compositons for nasal administration of pharmaceuticals |
US8435539B2 (en) | 2004-02-13 | 2013-05-07 | Immunomedics, Inc. | Delivery system for cytotoxic drugs by bispecific antibody pretargeting |
US8435002B2 (en) | 2004-08-30 | 2013-05-07 | Lord Corporation | Helicopter vibration control system and rotating assembly rotary forces generators for canceling vibrations |
US8435289B2 (en) | 2005-02-11 | 2013-05-07 | Abbott Medical Optics Inc. | Rapid exchange IOL insertion apparatus and methods of using |
US8435745B2 (en) | 2005-02-14 | 2013-05-07 | Zymogenetics, Inc. | Methods of using IL-31 antagonists in diseases mediated by cutaneous lymphocyte antigen positive T cells |
US8435540B2 (en) | 2005-04-06 | 2013-05-07 | Ibc Pharmaceuticals, Inc. | Dimeric alpha interferon PEGylated site-specifically shows enhanced and prolonged efficacy in VIVO |
US8435785B2 (en) | 2005-06-01 | 2013-05-07 | Wisconsin Alumni Research Foundation | Method of forming dendritic cells from embryonic stem cells |
US8435107B2 (en) | 2005-07-06 | 2013-05-07 | Wms Gaming Inc. | Wagering game system with networked gaming devices |
US8437712B2 (en) | 2005-10-27 | 2013-05-07 | Telecom Italia S.P.A. | Method and system for multiple antenna communications using multiple transmission modes, related apparatus and computer program product |
US8437964B2 (en) | 2005-12-19 | 2013-05-07 | Analiza, Inc. | Systems and methods involving data patterns such as spectral biomarkers |
US8434716B2 (en) | 2006-01-19 | 2013-05-07 | The Boeing Company | Compliant crown panel for an aircraft |
US8435276B2 (en) | 2006-02-27 | 2013-05-07 | Thomas Perez | Method and apparatus for the combined application of light therapy, optic diagnosis, and fluid to tissue |
US8435970B2 (en) | 2006-06-29 | 2013-05-07 | Astex Therapeutics Limited | Pharmaceutical combinations of 1-cyclopropyl-3-[3-(5-morpholin-4-ylmethyl-1H-benzoimidazol-2-yl)-1H-pyrazol-4-yl]-urea |
US8435761B2 (en) | 2006-06-29 | 2013-05-07 | Ucb Pharma Sa | DNA encoding antibody molecules which bind human IL-17 |
US8436436B2 (en) | 2006-08-01 | 2013-05-07 | Washington University | Multifunctional nanoscopy for imaging cells |
US8437224B2 (en) * | 2006-08-03 | 2013-05-07 | Wfs Technologies Ltd. | Underwater communications |
US8435476B2 (en) | 2006-08-03 | 2013-05-07 | Spawnt Private S.A.R.L. | Process for supplying a fuel cell with hydrogen by means of silanes or polysilanes |
US8435383B2 (en) | 2006-08-25 | 2013-05-07 | Edwin X Graf | Process and machine for making air dried tissue |
US8435775B2 (en) | 2006-09-06 | 2013-05-07 | Medical Research Council | Mutant Pfu DNA polymerase |
US8435978B2 (en) * | 2006-09-29 | 2013-05-07 | Gruenenthal Gmbh | Substituted sulfonamide compounds |
US8436546B2 (en) | 2006-10-20 | 2013-05-07 | Luxim Corporation | Electrodeless lamps and methods |
US8436149B2 (en) | 2006-10-27 | 2013-05-07 | Abbvie Biotechnology Ltd | Crystalline anti-hTNFalpha antibodies |
US8434311B2 (en) | 2006-11-01 | 2013-05-07 | Alstom Technology Ltd. | System for controlling a combustion process for a gas turbine |
US8435207B2 (en) | 2006-11-06 | 2013-05-07 | Aardvark Medical, Inc. | Irrigation and aspiration devices and methods |
US8436035B2 (en) | 2006-12-18 | 2013-05-07 | Novartis Ag | Organic compounds |
US8435560B2 (en) | 2006-12-28 | 2013-05-07 | Dow Corning Corporation | Polynuclear microcapsules |
US8435752B2 (en) | 2007-01-18 | 2013-05-07 | University Of Southern California | Gene polymorphisms predictive for dual TKI therapy |
US8434285B2 (en) | 2007-01-19 | 2013-05-07 | Steven L. Harrison | Tiled transition bracketing |
US8437845B2 (en) | 2007-02-01 | 2013-05-07 | Ls Biopath, Inc. | Electrical methods for detection and characterization of abnormal tissue and cells |
US8435552B2 (en) | 2007-02-09 | 2013-05-07 | Royal College Of Surgeons In Ireland | Collagen/hydroxyapatite composite scaffold, and process for the production thereof |
US8437792B2 (en) | 2007-02-14 | 2013-05-07 | Qualcomm Incorporated | Uplink power control for LTE |
US8434972B2 (en) | 2007-02-17 | 2013-05-07 | Hartmetall-Werkzeugfabrik Paul Horn Gmbh | Broaching tool, in particular keyway broaching tool |
US8435428B2 (en) | 2007-02-21 | 2013-05-07 | Air Liquide Electronics U.S. Lp | Methods for forming a ruthenium-based film on a substrate |
US8437286B2 (en) | 2007-02-22 | 2013-05-07 | Zte (Usa) Inc. | Signaling for multi-hop relay in wireless communication systems |
US8434236B2 (en) * | 2007-02-26 | 2013-05-07 | Pellenc (Societe Anonyme) | Chain saw with tension adjustment |
US8435984B2 (en) | 2007-02-26 | 2013-05-07 | Achillion Pharmaceuticals, Inc. | Tertiary amine substituted peptides useful as inhibitors of HCV replication |
US8435636B2 (en) | 2007-03-29 | 2013-05-07 | Akron Polymer Systems, Inc. | Optical compensation films of brominated styrenic polymers and related methods |
US8434195B2 (en) | 2007-04-05 | 2013-05-07 | Siemens Ag Österreich | Door rail and door attachment system for passenger rail cars |
US8435769B2 (en) | 2007-04-13 | 2013-05-07 | Monsanto Technology Llc | Use of glyphosate to produce shikimic acid in microorganisms |
US8435987B2 (en) | 2007-05-07 | 2013-05-07 | Amgen Inc. | Pyrazolo-pyridinone and pyrazolo-pyrazinone compounds as P38 modulators and methods of use thereof |
US8435770B2 (en) | 2007-05-09 | 2013-05-07 | Mascoma Corporation | Gene knockout mesophilic and thermophilic organisms, and methods of use thereof |
US8437057B2 (en) | 2007-05-16 | 2013-05-07 | Seereal Technologies S.A. | Method for rendering and generating color video holograms in real time |
US8437357B2 (en) | 2007-05-29 | 2013-05-07 | Packetfront Network Products Ab | Method of connecting VLAN systems to other networks via a router |
US8434522B2 (en) | 2007-05-31 | 2013-05-07 | Tokyo Electron Limited | Fluid control apparatus |
US8437293B2 (en) | 2007-06-19 | 2013-05-07 | Telefonaktiebolaget L M Ericsson (Publ) | Methods and systems for scheduling resources in a telecommunication system |
US8436028B2 (en) | 2007-06-20 | 2013-05-07 | Merck Sharp & Dohme Corp | CETP inhibitors derived from benzoxazole arylamides |
US8435928B2 (en) | 2007-07-13 | 2013-05-07 | Ishihara Sangyo Kaisha, Ltd. | Herbicidal composition |
US8435446B2 (en) | 2007-07-25 | 2013-05-07 | Alcoa Inc. | Surfaces and coatings for the removal of carbon dioxide |
US8434872B2 (en) | 2007-07-30 | 2013-05-07 | National Institute Of Information And Communications Technology | Multi-viewpoint floating image display device |
US8435997B2 (en) | 2007-08-10 | 2013-05-07 | Marquette University | Cysteine prodrugs to treat schizophrenia and drug addiction |
US8435999B2 (en) | 2007-08-13 | 2013-05-07 | Monsanto Technology Llc | Compositions and methods for controlling nematodes |
US8435725B2 (en) | 2007-09-20 | 2013-05-07 | Agfa-Gevaert Nv | Security laminates with interlaminated transparent embossed polymer hologram |
US8884448B2 (en) | 2007-09-28 | 2014-11-11 | Tessera, Inc. | Flip chip interconnection with double post |
EP2637202A2 (en) | 2007-09-28 | 2013-09-11 | Tessera, Inc. | Flip chip interconnection with etched posts on a microelectronic element joined to etched posts on a substrate by a fusible metal and corresponding manufacturing method |
WO2009043115A1 (en) * | 2007-10-04 | 2009-04-09 | Fermiscan Australia Pty Limited | Method for identifying biomarkers which are diagnostic for a pathological condition |
US8438020B2 (en) | 2007-10-12 | 2013-05-07 | Panasonic Corporation | Vector quantization apparatus, vector dequantization apparatus, and the methods |
US8436334B2 (en) | 2007-10-12 | 2013-05-07 | Agency For Science, Technology And Research | Fabrication of phosphor free red and white nitride-based LEDs |
US8434893B2 (en) | 2007-10-17 | 2013-05-07 | Lsi Industries, Inc. | Luminaire and methods of use |
US8435742B2 (en) | 2007-11-01 | 2013-05-07 | Yamaguchi University | Method and kit for detection/quantification of target RNA |
US8435701B2 (en) * | 2007-11-27 | 2013-05-07 | Southbourne Investments Ltd. | Holographic recording medium |
US8435319B2 (en) | 2007-12-07 | 2013-05-07 | Cedric Dackam | Filter unit for the filtration of gaseous fluids, in particular air filter in internal combustion engines |
US8434344B2 (en) * | 2007-12-12 | 2013-05-07 | Service Solutions U.S. Llc | Verification of scale calibration method and apparatus |
US8435119B2 (en) | 2007-12-26 | 2013-05-07 | Scientific Games Holdings Limited | User-controlled sweepstakes entries |
US8436156B2 (en) | 2008-01-04 | 2013-05-07 | Tate & Lyle Technology Limited | Method for the production of sucralose |
US8436185B2 (en) | 2008-01-08 | 2013-05-07 | Merck Sharp & Dohme Corp. | Pharmaceutically acceptable salts of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide |
US8437997B2 (en) | 2008-01-22 | 2013-05-07 | Exxonmobil Upstream Research Company | Dynamic connectivity analysis |
US8436762B2 (en) | 2008-01-31 | 2013-05-07 | Bae Systems Information And Electronic Systems Integration Inc. | Determining at least one coordinate of an object using intersecting surfaces |
US8436171B2 (en) | 2008-02-01 | 2013-05-07 | Akinion Pharmaceuticals Ab | Amino substituted pyrazines as inhibitors or protein kinases |
US8437963B2 (en) | 2008-02-08 | 2013-05-07 | Annica Önell | Method, computer program product and system for enabling clinical decision support |
US8434703B2 (en) | 2008-02-15 | 2013-05-07 | E2V Technologies (Uk) Limited | Apparatus and method for comminution of mineral ore |
US8435721B2 (en) | 2008-02-21 | 2013-05-07 | Nissan Chemical Industries, Ltd. | Resist underlayer film forming composition and forming method of resist pattern using the same |
US8437069B2 (en) | 2008-03-11 | 2013-05-07 | Sipix Imaging, Inc. | Luminance enhancement structure for reflective display devices |
US8434719B2 (en) | 2008-03-13 | 2013-05-07 | Patria Acostructures Oy | Leading edge element of aircraft, method for manufacturing one, wing and stabilizer |
US8437067B2 (en) | 2008-03-18 | 2013-05-07 | Konica Minolta Holdings, Inc. | Electrochemical display element |
US8437858B2 (en) | 2008-03-18 | 2013-05-07 | Imi Intelligent Medical Implants, Ag | Visual prosthesis system for displaying video image and text data |
US8436157B2 (en) | 2008-03-26 | 2013-05-07 | Tate & Lyle Technology Limited | Method for the production of sucralose |
US8436005B2 (en) | 2008-04-03 | 2013-05-07 | Abbott Laboratories | Macrocyclic pyrimidine derivatives |
US8436078B2 (en) * | 2008-04-28 | 2013-05-07 | Kuraray Noritake Dental Inc. | Dental composition and composite resin |
US8437418B2 (en) | 2008-04-30 | 2013-05-07 | Huawei Technologies Co., Ltd. | Method and apparatus for detecting signals of multi-input multi-output system |
US8436510B2 (en) * | 2008-04-30 | 2013-05-07 | Murata Manufacturing Co., Ltd. | Boundary acoustic wave device |
US8435555B2 (en) | 2008-05-01 | 2013-05-07 | Eminate Limited | Salt product |
EP2617794A2 (en) | 2008-05-07 | 2013-07-24 | E. I. du Pont de Nemours and Company | Compositions comprising 2,3,3,3- tetrafluoropropene |
US8435771B2 (en) | 2008-05-07 | 2013-05-07 | Novozymes A/S | Fermentation of a lignocellulose-containing material |
WO2009135902A2 (en) | 2008-05-07 | 2009-11-12 | Vestas Wind Systems A/S | A sectional blade |
US8435992B2 (en) | 2008-05-16 | 2013-05-07 | Pharma Mar S.A. | Multiple myeloma treatments |
US8435313B2 (en) | 2008-05-19 | 2013-05-07 | Furanix Technologies, B.V. | Fuel composition |
US8436182B2 (en) | 2008-05-23 | 2013-05-07 | Zaklady Farmaceutyczne Polpharma Sa | Process for preparation of solifenacin and/or the pharmaceutically acceptable salts thereof of high pharmaceutical purity |
US8437570B2 (en) | 2008-05-23 | 2013-05-07 | Microsoft Corporation | Geodesic image and video processing |
US8434913B2 (en) | 2008-05-30 | 2013-05-07 | Koninklijke Philips Electronics N.V. | Round illumination device |
US8434605B2 (en) | 2008-06-06 | 2013-05-07 | Nsk-Warner K.K. | One-way clutch of roller type for starter of motor bike |
US8436158B2 (en) | 2008-06-18 | 2013-05-07 | Pfizer Inc. | Antibodies to IL-6 and their uses |
US8435749B2 (en) | 2008-06-30 | 2013-05-07 | Oncotherapy Science, Inc. | Anti-CDH3 antibodies labeled with radioisotope label and uses thereof |
US8436537B2 (en) | 2008-07-07 | 2013-05-07 | Samsung Sdi Co., Ltd. | Substrate structure for plasma display panel, method of manufacturing the substrate structure, and plasma display panel including the substrate structure |
US8435513B2 (en) | 2008-07-08 | 2013-05-07 | Oncomed Pharmaceuticals, Inc. | NOTCH1 receptor antibodies and methods of treatment |
US8436011B2 (en) | 2008-07-08 | 2013-05-07 | Sanofi | Pyridinopyridinone derivatives, preparation thereof and therapeutic use thereof |
US8434323B2 (en) | 2008-07-14 | 2013-05-07 | Johnson Controls Technology Company | Motor cooling applications |
US8435524B2 (en) | 2008-07-16 | 2013-05-07 | Institute For Research In Biomedicine | Human cytomegalovirus neutralizing antibodies and use thereof |
US8436134B2 (en) | 2008-07-18 | 2013-05-07 | University Of Chicago | Semiconducting polymers |
US8436012B2 (en) | 2008-08-05 | 2013-05-07 | Daiichi Sankyo Company, Limited | Imidazopyridin-2-one derivatives |
US8437228B2 (en) | 2008-08-06 | 2013-05-07 | Hitachi, Ltd. | Thermally-assisted magnetic recording head |
US8435986B2 (en) | 2008-08-14 | 2013-05-07 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Bicyclic traizole derivatives for treating of tumors |
US8434190B2 (en) | 2008-09-01 | 2013-05-07 | Braun Gmbh | Toothbrush and method of manufacturing it |
US8437857B2 (en) | 2008-09-04 | 2013-05-07 | Boston Scientific Neuromodulation Corporation | Multiple tunable central cathodes on a paddle for increased medial-lateral and rostral-caudal flexibility via current steering |
US8434372B2 (en) | 2008-09-12 | 2013-05-07 | Fras Technology As | Fluid analysis system and method for operation of an analysis system |
US8436015B2 (en) | 2008-09-15 | 2013-05-07 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
US8436090B2 (en) | 2008-09-16 | 2013-05-07 | Nippon Shokubai Co., Ltd. | Production method and method for enhancing liquid permeability of water-absorbing resin |
US8435968B2 (en) | 2008-09-19 | 2013-05-07 | Pimco 2664 Limited | Aryl-phenyl-sulfonamido-cycloalkyl compounds and their use |
US8435751B2 (en) | 2008-09-25 | 2013-05-07 | Gambro Lundia Ab | Membrane for cell expansion |
US8437394B2 (en) | 2008-09-25 | 2013-05-07 | Mediatek Inc. | Adaptive filter |
US8438616B2 (en) | 2008-09-28 | 2013-05-07 | Huawei Technologies Co., Ltd. | Method for terminal configuration and management and terminal device |
US8436312B2 (en) * | 2008-10-08 | 2013-05-07 | National Institute Of Radiological Sciences | DOI type radiation detector |
US8436213B2 (en) | 2008-10-10 | 2013-05-07 | Exxonmobil Chemical Patents Inc. | Process for producing phenol and methyl ethyl ketone |
US8434659B2 (en) * | 2008-10-14 | 2013-05-07 | Hesse & Knipps Gmbh | Bonding device, ultrasonic transducer, and bonding method |
US8436413B2 (en) | 2008-10-15 | 2013-05-07 | Indian Institute Of Technology, Bombay | Nonvolatile floating gate analog memory cell |
US8436205B2 (en) | 2008-10-23 | 2013-05-07 | Actelion Pharmaceuticals Ltd. | Tetrahydronaphthalene compounds |
US8435325B2 (en) | 2008-10-23 | 2013-05-07 | Hitachi, Ltd. | Method and device for removing CO2 and H2S |
US8436110B2 (en) | 2008-10-31 | 2013-05-07 | Dow Global Technologies Llc | Olefin metathesis process employing bimetallic ruthenium complex with bridging hydrido ligands |
US8437247B2 (en) | 2008-10-31 | 2013-05-07 | Htc Corporation | Methods of packet element transmission in wireless communications system |
US8436875B2 (en) | 2008-11-13 | 2013-05-07 | Sharp Kabushiki Kaisha | Display device |
US8436200B2 (en) | 2008-11-18 | 2013-05-07 | Takeda Pharmaceutical Company Limited | Process for making (R)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-flouro-4- iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione and intermediates thereof |
US8438479B2 (en) | 2008-11-25 | 2013-05-07 | Panasonic Corporation | Operation support apparatus and method of the same |
US8437114B2 (en) | 2008-11-26 | 2013-05-07 | Murata Manufacturing Co., Ltd. | ESD Protection Device |
US8436459B2 (en) | 2008-11-28 | 2013-05-07 | Mitsubishi Electric Corporation | Power semiconductor module |
US8436137B2 (en) | 2008-12-03 | 2013-05-07 | Koji Kawakami | Selective anticancer chimeric peptide comprising an EGF receptor-binding peptide and a cytotoxic peptide |
US8436820B2 (en) | 2008-12-04 | 2013-05-07 | Electronics And Telecommunications Research Institute | Touchpad using resistive electro-conductive fiber and input device having the same |
US8436925B2 (en) | 2008-12-08 | 2013-05-07 | Sony Corporation | Solid-state imaging device, method for processing signal of solid-state imaging device, and imaging apparatus |
US8436444B2 (en) * | 2008-12-10 | 2013-05-07 | Si-Nano Inc. | Thin film photoelectric conversion device and method for manufacturing thin film photoelectric conversion device |
US8436862B2 (en) | 2008-12-11 | 2013-05-07 | Nvidia Corporation | Method and system for enabling managed code-based application program to access graphics processing unit |
US8436614B2 (en) | 2008-12-17 | 2013-05-07 | Siemens Aktiengesellschaft | Local coil arrangement for magnetic resonance applications with activatable marker |
US8434581B2 (en) | 2008-12-19 | 2013-05-07 | Zf Friedrichshafen Ag | Suspension device having anti-roll compensation |
US8436008B2 (en) | 2008-12-22 | 2013-05-07 | Incyte Corporation | Substituted heterocyclic compounds |
US8436270B2 (en) | 2008-12-22 | 2013-05-07 | Hypertherm, Inc. | Method and apparatus for cutting high quality internal features and contours |
US8435917B2 (en) | 2008-12-23 | 2013-05-07 | Sued-Chemie Catalysts Italia S.R.L. | Ammonia oxidation catalysts |
US8436054B2 (en) | 2008-12-23 | 2013-05-07 | E I Du Pont De Nemours And Company | Fluorinated ionomer produced by aqueous polymerization using dispersed particulate of fluorinated ionomer produced in situ |
US8436053B2 (en) | 2008-12-23 | 2013-05-07 | E.I. Du Pont De Nemours And Company | Fluorinated ionomer produced by aqueous polymerization using dispersed particulate of fluorinated ionomer |
US8438452B2 (en) | 2008-12-29 | 2013-05-07 | Intel Corporation | Poison bit error checking code scheme |
US8435355B2 (en) | 2008-12-29 | 2013-05-07 | Weyerhaeuser Nr Company | Fractionation of lignocellulosic material using ionic liquids |
US8435648B2 (en) * | 2008-12-30 | 2013-05-07 | Cheil Industries, Inc. | Pyridinylene ring compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode |
US8436342B2 (en) | 2009-01-12 | 2013-05-07 | Samsung Display Co., Ltd. | Organic light emitting display device and method of manufacturing the same |
US8436092B2 (en) | 2009-01-16 | 2013-05-07 | Tsinghua University | Giant magnetoresistance composite material containing carbon nanotubes |
US8436791B2 (en) * | 2009-01-26 | 2013-05-07 | Seiko Epson Corporation | Light-emitting device and mobility compensating method for driving the same, and electronic device |
US8435768B2 (en) | 2009-01-30 | 2013-05-07 | Ajinomoto Co., Inc. | Method for producing succinic acid using a yeast belonging to the genus Yarrowia |
US8435995B2 (en) | 2009-02-05 | 2013-05-07 | Takeda Pharmaceutical Company Limited | Pyridazinone compounds |
US8435064B2 (en) | 2009-02-12 | 2013-05-07 | Fronius International Gmbh | Mounting for a DC-AC converter and method for fitting a DC-AC converter |
US8436918B2 (en) | 2009-02-27 | 2013-05-07 | Deluxe Laboratories, Inc. | Systems, apparatus and methods for subtitling for stereoscopic content |
US8436488B2 (en) * | 2009-03-03 | 2013-05-07 | Bluewater Energy Services B.V. | Semi-direct variable speed drive with N+1 power availability |
US8437806B2 (en) | 2009-03-03 | 2013-05-07 | Lg Electronics Inc. | Mobile terminal and method for displaying data in mobile terminal |
US8435766B2 (en) | 2009-03-19 | 2013-05-07 | N.V. Desmet Ballestra Engineering S.A. | Enzymatic oil recuperation process |
US8436754B2 (en) | 2009-03-27 | 2013-05-07 | Huawei Technologies Co., Ltd. | Encoding and decoding method and device |
US8436069B2 (en) | 2009-03-30 | 2013-05-07 | Fujifilm Corporation | Ink composition |
EP2623101A1 (en) | 2009-04-02 | 2013-08-07 | Merck Patent GmbH | Piperidine and piperazine derivatives as autotaxin inhibitors |
EP2623491A2 (en) | 2009-04-02 | 2013-08-07 | Merck Patent GmbH | Piperidine and piperazine derivatives as autotaxin inhibitors |
EP2626072A1 (en) | 2009-04-02 | 2013-08-14 | Merck Patent GmbH | Piperidine and piperazine derivatives as autotaxin inhibitors |
US8435272B2 (en) | 2009-04-09 | 2013-05-07 | Arthrex, Inc. | Clavicle nail with locking end cap |
US8435056B2 (en) | 2009-04-16 | 2013-05-07 | Enphase Energy, Inc. | Apparatus for coupling power generated by a photovoltaic module to an output |
US8434781B2 (en) | 2009-04-16 | 2013-05-07 | Doona Holdings Ltd | Baby safety car seat convertible into a rollable baby seat |
US8434422B2 (en) | 2009-04-20 | 2013-05-07 | Dow Global Technologies Llc | Coating apparatus and method |
US8436036B2 (en) | 2009-04-24 | 2013-05-07 | Janssen R&D Ireland | Diaryl ethers |
US8437798B2 (en) | 2009-04-27 | 2013-05-07 | Motorola Mobility Llc | Uplink scheduling support in multi-carrier wireless communication systems |
US8438210B2 (en) | 2009-05-04 | 2013-05-07 | Comcast Cable Communications, Llc | Sharing media content based on a media server |
US8435523B2 (en) | 2009-05-04 | 2013-05-07 | Abbott Research B.V. | Antibodies against nerve growth factor (NGF) with enhanced in vivo stability |
US8435914B2 (en) | 2009-05-14 | 2013-05-07 | Univation Technologies, Llc | Mixed metal catalyst systems having a tailored hydrogen response |
US8437083B2 (en) | 2009-05-21 | 2013-05-07 | Canon Kabushiki Kaisha | Optical element, optical system including the optical element, and optical apparatus including the optical system |
US8437970B2 (en) | 2009-06-05 | 2013-05-07 | Apple Inc. | Restoring and storing magnetometer calibration data |
US8434488B2 (en) | 2009-06-08 | 2013-05-07 | Covidien Lp | Endotracheal tube with dedicated evacuation port |
EP2440937A1 (en) * | 2009-06-12 | 2012-04-18 | SBC Research Pty Ltd | A diagnostic method |
WO2011000020A1 (en) * | 2009-06-12 | 2011-01-06 | Sbc Research Pty Ltd | Enhanced method of detection |
EP2440937A4 (en) * | 2009-06-12 | 2013-05-29 | Sbc Res Pty Ltd | A diagnostic method |
US8437597B2 (en) | 2009-06-19 | 2013-05-07 | Corning Cable Systems Llc | Mounting of fiber optic cable assemblies within fiber optic shelf assemblies |
US8437332B2 (en) | 2009-06-22 | 2013-05-07 | Qualcomm Incorporated | Low complexity unified control channel processing |
US8435961B2 (en) | 2009-06-26 | 2013-05-07 | Massachusetts Institute Of Technology | Methods and compositions for increasing the activity of inhibitory RNA |
US8437827B2 (en) | 2009-06-30 | 2013-05-07 | Abbott Diabetes Care Inc. | Extruded analyte sensors and methods of using same |
US8437278B2 (en) | 2009-07-02 | 2013-05-07 | Seiko Epson Corporation | Service providing apparatus for digital processing service, wireless communication system, and wireless communication method |
US8436102B2 (en) | 2009-07-06 | 2013-05-07 | Denki Kagaku Kogyo Kabushiki Kaisha | Polychloroprene latex composition, process for production of same, and products of forming thereof |
US8435454B2 (en) | 2009-07-09 | 2013-05-07 | Siemens Medical Solutions Usa, Inc. | Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure |
US8435980B2 (en) | 2009-07-15 | 2013-05-07 | Abbvie Inc. | Pyrrolopyridine inhibitors of kinases |
US8434647B2 (en) | 2009-08-08 | 2013-05-07 | Riad Aamar | Device for measuring and dispensing a prescribed amount of liquid |
US8435228B2 (en) | 2009-08-12 | 2013-05-07 | Medrad, Inc. | Interventional catheter assemblies incorporating guide wire brake and management systems |
US8438600B2 (en) | 2009-08-20 | 2013-05-07 | Lg Electronics Inc. | Method of processing EPG metadata in network device and network device for controlling the same |
US8434877B2 (en) | 2009-08-20 | 2013-05-07 | Canon Kabushiki Kaisha | Illumination optical system and projection display apparatus |
US8436172B2 (en) | 2009-08-31 | 2013-05-07 | Udc Ireland Limited | Material selecting method upon purifying iridium complex by sublimation |
US8434718B2 (en) | 2009-09-02 | 2013-05-07 | Eurocopter | Reusable rotorcraft bumper, and a rotorcraft having such a bumper |
US8435976B2 (en) | 2009-09-08 | 2013-05-07 | F. Hoffmann-La Roche | 4-substituted pyridin-3-yl-carboxamide compounds and methods of use |
US8437951B2 (en) | 2009-09-14 | 2013-05-07 | Research In Motion Limited | Methods, device and systems for determining route metrics using stored route information |
US8434308B2 (en) | 2009-09-15 | 2013-05-07 | General Electric Company | Heat pipes for transferring heat to an organic rankine cycle evaporator |
US8436295B2 (en) | 2009-09-15 | 2013-05-07 | Canon Anelva Corporation | Device for measuring mean free path, vacuum gauge, and method for measuring mean free path |
US8436944B2 (en) | 2009-10-01 | 2013-05-07 | Panasonic Corporation | Wireless communications system, adaptor apparatus for video apparatus, video apparatus and control method for wireless communications system |
US8436024B2 (en) | 2009-10-02 | 2013-05-07 | Astrazeneca Ab | 2-pyridone compounds |
US8438021B2 (en) | 2009-10-15 | 2013-05-07 | Huawei Technologies Co., Ltd. | Signal classifying method and apparatus |
US8436002B2 (en) | 2009-10-23 | 2013-05-07 | Eli Lilly And Company | AKT inhibitors |
US8436698B2 (en) | 2009-11-02 | 2013-05-07 | Harris Corporation | MEMS-based tunable filter |
US8435246B2 (en) | 2009-11-02 | 2013-05-07 | Synvasive Technology, Inc. | Knee arthroplasty apparatus and method |
US8435341B2 (en) | 2009-11-03 | 2013-05-07 | Agfa-Gevaert N.V. | Preparing and dispersing surface-modified colour pigments |
US8437308B2 (en) | 2009-11-05 | 2013-05-07 | Telefonaktiebolaget L M Ericsson (Publ) | Handover measurements in a mobile communication system |
US8435415B2 (en) | 2009-11-24 | 2013-05-07 | The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology | Nanofabrication process and nanodevice |
US8436833B2 (en) | 2009-11-25 | 2013-05-07 | Corning Incorporated | Methods and apparatus for sensing touch events on a display |
US8437962B2 (en) | 2009-11-25 | 2013-05-07 | Halliburton Energy Services, Inc. | Generating probabilistic information on subterranean fractures |
US8436491B2 (en) | 2009-11-30 | 2013-05-07 | Broadcom Corporation | Low pin count wireless power IC |
WO2011067465A1 (en) | 2009-12-04 | 2011-06-09 | Kristiina Rajala | Formulations and methods for culturing stem cells |
US8434383B2 (en) | 2009-12-04 | 2013-05-07 | Hyundai Motor Company | Transmission shifting apparatus for vehicle |
US8437773B2 (en) | 2009-12-09 | 2013-05-07 | Qualcomm Incorporated | Hierarchical information dissemination for location based systems |
US8434914B2 (en) | 2009-12-11 | 2013-05-07 | Osram Sylvania Inc. | Lens generating a batwing-shaped beam distribution, and method therefor |
US8435342B2 (en) | 2009-12-15 | 2013-05-07 | Shell Oil Company | Concrete composition |
US8437183B2 (en) | 2009-12-16 | 2013-05-07 | Sandisk Il Ltd. | Auxiliary parity bits for data written in multi-level cells |
US8435209B2 (en) | 2009-12-30 | 2013-05-07 | Medtronic Minimed, Inc. | Connection and alignment detection systems and methods |
US8438231B2 (en) | 2010-01-08 | 2013-05-07 | Alcatel Lucent | Telecommunication messaging through a social networking service |
US8435828B2 (en) | 2010-01-13 | 2013-05-07 | Renesas Electronics Corporation | Method of manufacturing semiconductor device |
US8435792B2 (en) | 2010-01-14 | 2013-05-07 | Baxter International Inc. | Methods and compositions for treating bleeding disorders |
US8437794B2 (en) | 2010-01-28 | 2013-05-07 | Alcatel Lucent | Methods of determining uplink target signal-to-interfence-and-noise ratios and systems thereof |
US8436383B2 (en) * | 2010-02-17 | 2013-05-07 | Lg Innotek Co., Ltd. | Light emitting device, light emitting device package, and lighting system |
US8437882B2 (en) * | 2010-02-17 | 2013-05-07 | Inscope Energy, Llc | Managing power utilized within a local power network |
US8434906B2 (en) | 2010-02-23 | 2013-05-07 | General Electric Company | Lighting system with thermal management system |
WO2011104644A1 (en) | 2010-02-24 | 2011-09-01 | Koninklijke Philips Electronics N.V. | Hid lighting system |
WO2011104713A1 (en) | 2010-02-25 | 2011-09-01 | Nova Measuring Instruments Ltd. | Method and system for measurng in patterned structures |
US8434286B2 (en) | 2010-03-03 | 2013-05-07 | Yuyama Manufacturing Co., Ltd. | Medicament dispensing machine |
US8437594B2 (en) | 2010-03-16 | 2013-05-07 | Furukawa Electric Co., Ltd. | Holey fiber |
US8437173B2 (en) | 2010-03-19 | 2013-05-07 | Panasonic Corporation | Nonvolatile memory element, manufacturing method thereof, design support method therefor, and nonvolatile memory device |
US8434889B2 (en) | 2010-03-19 | 2013-05-07 | GE Lighting Solutions, LLC | Lighted display case having reduced glare |
US8436175B2 (en) | 2010-03-22 | 2013-05-07 | Rensselaer Polytechnic Institute | Carboxamide bioisosteres of opiates |
WO2011116811A1 (en) | 2010-03-24 | 2011-09-29 | Telefonaktiebolaget Lm Ericsson (Publ) | A node with an improved back up protocol |
US8435402B2 (en) * | 2010-03-29 | 2013-05-07 | Marathon Canadian Oil Sands Holding Limited | Nozzle reactor and method of use |
US8436060B2 (en) | 2010-03-30 | 2013-05-07 | Samsung Electronics Co., Ltd. | Organic aerogel and composition for the organic aerogel |
US8436065B2 (en) | 2010-04-01 | 2013-05-07 | Samsung Electronics Co., Ltd. | Aerogel, and composition and method for manufacture of the aerogel |
US8436512B2 (en) | 2010-04-06 | 2013-05-07 | Senseor | Method of rapidly interrogating elastic wave sensors |
US8436001B2 (en) | 2010-04-07 | 2013-05-07 | F. Hoffmann-La Roche Ag | Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use |
US8435778B2 (en) | 2010-05-13 | 2013-05-07 | Suntory Holdings Limited | Gene encoding lignan methyltransferase and use thereof |
US8436755B2 (en) | 2010-05-21 | 2013-05-07 | Research In Motion Limited | Methods and devices for reducing sources in binary entropy coding and decoding |
US8435486B2 (en) * | 2010-05-24 | 2013-05-07 | Toyota Jidosha Kabushiki Kaisha | Redox material for thermochemical water splitting, and method for producing hydrogen |
US8436218B2 (en) | 2010-05-27 | 2013-05-07 | Honeywell International Inc. | Azeotrope-like composition of hexafluoropropane, hexafluoropropene and hydrogen fluoride |
US8435409B2 (en) | 2010-05-28 | 2013-05-07 | Ecolab Usa Inc. | Activated sludge process in wastewater treatment |
US8434910B2 (en) | 2010-06-01 | 2013-05-07 | Lg Innotek Co., Ltd. | Light emitting device package and lighting system |
US8437527B2 (en) | 2010-06-16 | 2013-05-07 | Hitachi Aloka Medical, Ltd. | Ultrasound diagnostic apparatus |
US9030001B2 (en) | 2010-07-27 | 2015-05-12 | Tessera, Inc. | Microelectronic packages with nanoparticle joining |
US9397063B2 (en) | 2010-07-27 | 2016-07-19 | Tessera, Inc. | Microelectronic packages with nanoparticle joining |
US8434184B2 (en) | 2010-08-13 | 2013-05-07 | Braun Gmbh | Fracture resistant brush head |
US8434183B2 (en) | 2010-08-13 | 2013-05-07 | Braun Gmbh | Brush section for an electric toothbrush |
US8434776B2 (en) | 2010-08-16 | 2013-05-07 | Andy WUTHRICH | Bicycle frame with rear suspension system |
US8438272B2 (en) | 2010-08-31 | 2013-05-07 | Sap Ag | Methods and systems for managing quality of services for network participants in a networked business process |
US8434242B2 (en) | 2010-09-16 | 2013-05-07 | Velico Medical, Inc. | Spray dried human plasma |
WO2012043067A1 (en) | 2010-09-27 | 2012-04-05 | 日本電気株式会社 | Vehicle-mounted device and congestion control method |
WO2012043801A1 (en) | 2010-09-30 | 2012-04-05 | 積水メディカル株式会社 | Patch |
US8435988B2 (en) | 2010-10-06 | 2013-05-07 | Glaxosmithkline Llc | Benzimidazole derivatives as P13 kinase inhibitors |
US8436114B2 (en) | 2010-10-21 | 2013-05-07 | Exxonmobil Chemical Patents Inc. | Polyethylene and process for production thereof |
US8434460B2 (en) | 2010-10-29 | 2013-05-07 | Ford Global Technologies, Llc | Integrally molded carbon canister |
WO2012070099A1 (en) | 2010-11-22 | 2012-05-31 | 東芝三菱電機産業システム株式会社 | Rolling mill control device |
US8435993B2 (en) | 2010-12-07 | 2013-05-07 | Philadelphia Health And Education Corporation | Methods of inhibiting metastasis from cancer |
US9496236B2 (en) | 2010-12-10 | 2016-11-15 | Tessera, Inc. | Interconnect structure |
US8438044B2 (en) | 2011-01-18 | 2013-05-07 | Audiahealth, Llc | Systems and methods combining print and audio technologies to deliver and personalize health information |
US8437177B2 (en) | 2011-01-20 | 2013-05-07 | Panasonic Corporation | Nonvolatile latch circuit and nonvolatile flip-flop circuit |
US8434524B2 (en) | 2011-01-31 | 2013-05-07 | Vanderbilt University | Elastic hydraulic accumulator/reservoir system |
US8435275B2 (en) | 2011-03-30 | 2013-05-07 | Valkee Oy | Portable ear light device |
US8437079B2 (en) | 2011-05-06 | 2013-05-07 | Leapers, Inc. | Apparatus including a reticle, assembly and method for operating the same |
US8435545B2 (en) * | 2011-09-01 | 2013-05-07 | Qualicaps, Inc. | Capsule having broad color spectrum |
WO2013124832A2 (en) | 2012-02-24 | 2013-08-29 | Ranbaxy Laboratories Limited | Stabilized controlled-release pharmaceutical composition comprising gliclazide |
WO2013128380A1 (en) | 2012-02-28 | 2013-09-06 | Koninklijke Philips N.V. | Device for light based skin treatment |
WO2013128369A1 (en) | 2012-02-28 | 2013-09-06 | Koninklijke Philips N.V. | Aed with compression sensor |
WO2013132448A1 (en) | 2012-03-07 | 2013-09-12 | Kba-Notasys Sa | Method of checking producibility of a composite security design of a security document on a line of production equipment and digital computer environment for implementing the same |
WO2013156630A1 (en) | 2012-04-20 | 2013-10-24 | Alphaptose Gmbh | S-enantiomer of a tri-substituted glycerol compound |
EP2796145A1 (en) | 2013-04-22 | 2014-10-29 | CSL Behring GmbH | Complex |
EP2796818A1 (en) | 2013-04-22 | 2014-10-29 | Shell Internationale Research Maatschappij B.V. | Method and apparatus for producing a liquefied hydrocarbon stream |
US9633971B2 (en) | 2015-07-10 | 2017-04-25 | Invensas Corporation | Structures and methods for low temperature bonding using nanoparticles |
US9818713B2 (en) | 2015-07-10 | 2017-11-14 | Invensas Corporation | Structures and methods for low temperature bonding using nanoparticles |
US10535626B2 (en) | 2015-07-10 | 2020-01-14 | Invensas Corporation | Structures and methods for low temperature bonding using nanoparticles |
US10886250B2 (en) | 2015-07-10 | 2021-01-05 | Invensas Corporation | Structures and methods for low temperature bonding using nanoparticles |
US10892246B2 (en) | 2015-07-10 | 2021-01-12 | Invensas Corporation | Structures and methods for low temperature bonding using nanoparticles |
US11710718B2 (en) | 2015-07-10 | 2023-07-25 | Adeia Semiconductor Technologies Llc | Structures and methods for low temperature bonding using nanoparticles |
WO2019186577A1 (en) | 2018-03-27 | 2019-10-03 | Council Of Scientific And Industrial Research | A non-invasive and remote method to screen cancer |
US11561187B2 (en) | 2018-03-27 | 2023-01-24 | Council Of Scientific And Industrial Research | Non-invasive and remote method to screen cancer |
Also Published As
Publication number | Publication date |
---|---|
TW200801513A (en) | 2008-01-01 |
EP2032031B1 (en) | 2011-08-17 |
AU2007264394A1 (en) | 2008-01-03 |
ATE520345T1 (en) | 2011-09-15 |
CN101478916A (en) | 2009-07-08 |
EP2032031A1 (en) | 2009-03-11 |
KR20090035556A (en) | 2009-04-09 |
KR101087576B1 (en) | 2011-11-29 |
ES2371368T3 (en) | 2011-12-30 |
JP2009541747A (en) | 2009-11-26 |
EP2032031A4 (en) | 2010-03-24 |
CA2652955A1 (en) | 2008-01-03 |
AU2007264394B2 (en) | 2012-08-16 |
US20090325303A1 (en) | 2009-12-31 |
AR061732A1 (en) | 2008-09-17 |
BRPI0713885A2 (en) | 2012-11-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2007264394B2 (en) | Improved process | |
Elkins | Rapid presumptive “fingerprinting” of body fluids and materials by ATR FT‐IR spectroscopy | |
CN105096225B (en) | The analysis system of aided disease diagnosis and treatment, device and method | |
Giori et al. | High-resolution gel electrophoresis and sodium dodecyl sulphate–agarose gel electrophoresis on urine samples for qualitative analysis of proteinuria in dogs | |
Klyuchko | Biotechnical information systems for monitoring of chemicals in environment: biophysical approach | |
Ghafar et al. | Comparative studies on faecal egg counting techniques used for the detection of gastrointestinal parasites of equines: A systematic review | |
JP3569231B2 (en) | Method for diagnosing TSE-induced tissue changes using infrared spectroscopy | |
Clark et al. | Lipid normalization and stable isotope discrimination in Pacific walrus tissues | |
Gao et al. | Sensitivity of sniffer dogs for a diagnosis of Parkinson's Disease: a diagnostic accuracy study | |
Mahmoud et al. | Two-step machine learning method for the rapid analysis of microvascular flow in intravital video microscopy | |
Tsongalis et al. | Applications of forensic identity testing in the clinical laboratory | |
Baptista et al. | Comparative study of inorganic elements determination in whole blood from Crioula breed horse by EDXRF and NAA analytical techniques | |
Giuseppe et al. | Preliminary study for the application of Raman spectroscopy for the identification of Leishmania infected dogs | |
Hawkins et al. | The Cu, Mn and Zn concentration of sheep wool: Influence of washing procedures, age and colour of matrix | |
JP2015505359A5 (en) | ||
Dove et al. | Spatio‐temporal variation in serum chemistry of the lobster, Homarus americanus Milne‐Edwards | |
US20050079099A1 (en) | Generation of biochemical images and methods of use | |
AU755041B2 (en) | Automated diagnostic system implementing immunoassays and clinical chemistry assays according to a reflex algorithm | |
Ansari-Lari et al. | Comparative study of plasma proteins including haptoglobin and serum amyloid A in different types of traumatic reticuloperitonitis in cattle | |
Cheleuitte-Nieves | Enrichment and outcomes in female lab mice | |
Miller et al. | Why do captive tufted capuchins (Cebus apella) urine wash? | |
Cunningham et al. | Tox/Path team takes on differential gene expression. | |
US20050112695A1 (en) | Method of detecting bovine spongiform encephalopathy | |
Morandi et al. | Endoparasites in dogs diagnosed at the Veterinary Teaching Hospital (VTH)-University of Bologna, combined with clinicopathological results. A long-term retrospective secondary data study | |
Bosco et al. | Comparison of Mini-FLOTAC, Flukefinder |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 200780024380.0 Country of ref document: CN |
|
DPE2 | Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 07719118 Country of ref document: EP Kind code of ref document: A1 |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2652955 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2007264394 Country of ref document: AU Ref document number: 573761 Country of ref document: NZ |
|
WWE | Wipo information: entry into national phase |
Ref document number: 5170/KOLNP/2008 Country of ref document: IN |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2007719118 Country of ref document: EP |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2009516820 Country of ref document: JP |
|
ENP | Entry into the national phase |
Ref document number: 2007264394 Country of ref document: AU Date of ref document: 20070627 Kind code of ref document: A |
|
NENP | Non-entry into the national phase |
Ref country code: RU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1020097001887 Country of ref document: KR Ref document number: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 12306134 Country of ref document: US |
|
ENP | Entry into the national phase |
Ref document number: PI0713885 Country of ref document: BR Kind code of ref document: A2 Effective date: 20081229 |