WO2011011808A1 - A cosmetic composition comprising sodium chloride in combination with one or more of protein, collagen, gelatin or amino acid - Google Patents

A cosmetic composition comprising sodium chloride in combination with one or more of protein, collagen, gelatin or amino acid Download PDF

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Publication number
WO2011011808A1
WO2011011808A1 PCT/AU2009/000963 AU2009000963W WO2011011808A1 WO 2011011808 A1 WO2011011808 A1 WO 2011011808A1 AU 2009000963 W AU2009000963 W AU 2009000963W WO 2011011808 A1 WO2011011808 A1 WO 2011011808A1
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WO
WIPO (PCT)
Prior art keywords
skin
substances
protein
combination
collagen
Prior art date
Application number
PCT/AU2009/000963
Other languages
French (fr)
Other versions
WO2011011808A8 (en
Inventor
Roman Buga
Original Assignee
Roman Buga
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roman Buga filed Critical Roman Buga
Priority to PCT/AU2009/000963 priority Critical patent/WO2011011808A1/en
Publication of WO2011011808A1 publication Critical patent/WO2011011808A1/en
Publication of WO2011011808A8 publication Critical patent/WO2011011808A8/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/01Hydrolysed proteins; Derivatives thereof
    • A61K38/012Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/014Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Definitions

  • Protein, Collagen or Gelatin have as naturally glue or binding-agents the best presupposition in this matter; additionally having all 3 substances some Amino acids integrated. Protein, collagen and gelatin bind the water and Salt(sodium chloride) in the best way; this gives us the best result what we need on the skin. We have a combination of water: which gives us the moisturizing and the salt which gives us the nutritionsupply.
  • CO2 it self is useful for the cosmetic surgeon or dermatologist to perform skin resurfacing what reduce or eliminate the pronounced lines and wrinkles and to stimulate the regeneration of a healthy skin underneath.
  • Amino acids essential or non essential have the capability to renew the skin-cells or other cells. It is a accelerator for woundhealing and faster grow of protein. Protein react faster in the grow specially with essential amino acids. Amino acids react fast, but don't can go a long distance in the acceleration.
  • the wound is closing faster as normal.
  • the salt combine with the amino acids and react to CO2, from now on the Protein/collagen/gelatin make a thin mask over the skin and slowing the process of the reaction down.
  • the protein or collagen or gelatin release slowly the amino acids and these is reacting slowly.
  • the Amino acids have a second task, its reacting with the skin and stimulate the growth of the cells in the skin, the gelatin/protein/collagen as mask over it gives the skin a smoother surface and the new
  • the 10 day cycle from 1 treatment the outer skin is smooth, but it get back to his old path after the 10 days; so when you want the new layers or the skin grow in the new path of the smooth outer skin, you need to hold the smooth skin in place for a minimum of 30 days(this is the cycle of the skin-growing-time).
  • the combination of salt its possible to treat scars or other skin-illness, but not open wounds(this can be painful).
  • the wound is open and need to stop the bleeding: the collagen stops with a thin skin over the wound the bleeding and the amino acids starts to stimulate the Protein-cells to stop the bleeding and to grow faster with the cells, so the wound close down faster. It can be any Protein-cell, from the tissue or from the blood.
  • This contraction can be done anywhere on the body. It is so strong you can shape a body with it and hold in position over a couple of days and with a stronger combination of the substances over a longer period up to 2 month with one treatment.

Abstract

A cosmetic composition comprising sodium chloride in combination with one or more of protein, collagen, gelatin or amino acid and its uses thereof.

Description

A COSMETIC COMPOSITION COMPRISING SODIUM CHLORIDE IN COMBINATION WITH ONE OR MORE OF PROTEIN, COLLAGEN, GELATIN OR AMINO ACID
Description:
[0001]Salt/Seasalt(sodium chloride) is used long time in History to heal
Skinillness.
To use this power not only in a bath, set asunder to have this the whole day on the skin, to get a long time healing-effect/nutritionsupply; we must bind it with some binding-agents.
[0002]Protein, Collagen or Gelatin have as naturally glue or binding-agents the best presupposition in this matter; additionally having all 3 substances some Amino acids integrated. Protein, collagen and gelatin bind the water and Salt(sodium chloride) in the best way; this gives us the best result what we need on the skin. We have a combination of water: which gives us the moisturizing and the salt which gives us the nutritionsupply.
[0003] With the water we bring the amino acids to the surface from the protein, collagen or gelatin. These Amino acids can now react with the salt(sodium chloride). The salt don't have only the work to do with the nutritionsupply, additionally it react with the amino acids and brings up the
[0004]CO2/carbon dioxide. CO2 it self is useful for the cosmetic surgeon or dermatologist to perform skin resurfacing what reduce or eliminate the pronounced lines and wrinkles and to stimulate the regeneration of a healthy skin underneath. We found out: amino acids and salt(sodium chloride) alone, react to strong to use it, self thinning with water was to strong or it doesn't worked any more.
[0005]Amino acids=essential or non essential have the capability to renew the skin-cells or other cells. It is a accelerator for woundhealing and faster grow of protein. Protein react faster in the grow specially with essential amino acids. Amino acids react fast, but don't can go a long distance in the acceleration.
[0006]And here comes the Protein or Collagen or Gelatin to it, with this 3 substances combine or ones itself, we get a continuous flow of amino acids.
Specially in the woundhealing, here gives us all three substances a good result. Its accelerate the working order of albumin and globulin in the blood.
The wound is closing faster as normal.
Treated with Salt and warm water, helped us to let the flow from CO2 to be slow and steady and another plus was the moisturizing with water to the skin, slow and steady; result: a Mask on the surface of the skin was created from the Protein or collagen or gelatin or combine together. [0007] After days it was still working with really good results. The skin contracted and all wrinkle are gone.
We achieve a result up to 10 days as this mask holding with this combination on a face of a woman under normal conditions / for a every day working person.
[0008]The high point of the CO2 treatment was on the 5 day. The skin was working 5 days with it and from the 5 day on it was going down to the 10 day. On the 11 day the Person looks like normal before and the skin had the same look as normal before. For a better result in healing of the skin or to get [0009] a better result in the treatment of the wrinkles/ageing of the skin, we will recommend a 4-5 day cycle, to get a optimum of a result, with a long time healing effect or a long time anti-wrinkle or anti-ageing result.
[0010]Protein or collagen or gelatin or combine the 3 together + Amino acids + Salt(sodium chloride) is a powerful and treatment combination, it doesn't matter the condition of these: in fluid form or in dry form, as powder or as granulate. In fluid-form for a roll on Bottle or other was created for a day to day basis.
[0011]In dry form as powder or granulate has the combination a more powerful form to reach a better result in what we want: anti-ageing and anti- wrinkle in our skin.
[0012]The salt(sodium chloride) is working as peeling on the skin, old
Skin scales get loose and the new skin underneath is free; the salt has the second work to sterilize the surface of the skin, make it ready for the treatment with the CO2; the third work is the release of minerals to the skin.
[0013] With the treatment of warm water, the salt combine with the amino acids and react to CO2, from now on the Protein/collagen/gelatin make a thin mask over the skin and slowing the process of the reaction down. The protein or collagen or gelatin release slowly the amino acids and these is reacting slowly.
[0014] The Amino acids have a second task, its reacting with the skin and stimulate the growth of the cells in the skin, the gelatin/protein/collagen as mask over it gives the skin a smoother surface and the new
growing/underneath, coming skin-cells don't grow in the path of the wrinkles, there grow straight in the path of the smoother skin, so does the [0015]new skin is smoother in the outcome of the treatment. Such a treatment takes time, it takes 30 days to change the surface of the skin, to grow the new layer of skin in the new path of the smoother surface from the holding mask.
[0016]To get a better understanding, the 10 day cycle from 1 treatment: the outer skin is smooth, but it get back to his old path after the 10 days; so when you want the new layers or the skin grow in the new path of the smooth outer skin, you need to hold the smooth skin in place for a minimum of 30 days(this is the cycle of the skin-growing-time). [0017]It is possible to add more amino acids to the powder/granulate, but be aware of the reaction of these, people can get headache or other problems. With the combination of salt its possible to treat scars or other skin-illness, but not open wounds(this can be painful).
[0018]For a wound it would be better a combination of Protein or collagen or gelatin with additional/supplementary amino acids in a small amount to get a reaction with the body, its stimulate the growth of the cells and gives him with the Protein/gelatin/collagen a naturally fine cover/skin to breath.
[0019] All amino acids can be used to stimulate the body-cells. We don't found a really big difference in the reacting with the body from different amino acids; but essential amino acids are generally better for the body-cells.
[0020]For the Wound-dressing: the wound is open and need to stop the bleeding: the collagen stops with a thin skin over the wound the bleeding and the amino acids starts to stimulate the Protein-cells to stop the bleeding and to grow faster with the cells, so the wound close down faster. It can be any Protein-cell, from the tissue or from the blood.
[0021]Important is the wound-dressing with the collagen + amino acids can be topped every time as it is needed, this gives these product a unique style. Self when the wound was dressed before with the collagen + amino acids, the amino acids with the new dressing found his way to stimulate the wound and there cells. For a better healing: the wound gets closed, here the collagen + amino acids stimulate the growth of the tissue.
[0022]Additional effects from amino acids and the 4 substances to the skin : the skin is getting lighten up and shiny, so people with dark rendering around the eyes or anywhere else, can use it to light up this problematic zones.
[0023] Additional effects to the skin: The combination of these Substances (Gelatin, Collagen, Protein, Amino acids, Sodium Chloride) alone or a variety from this cause a contraction of the skin, it can be so heavy the body- shape gets a new form. By some people lift the bottom/buttocks up, around 5 cm lift up the form, self around the thigh was the skin tighten up and give the person a nice strengthen feeling. Cellulite visible on buttocks or thigh, was after treatment gone or very hard to detect.
[0024] This contraction can be done anywhere on the body. It is so strong you can shape a body with it and hold in position over a couple of days and with a stronger combination of the substances over a longer period up to 2 month with one treatment.
This can be used as surgical compression like the compression
stockings/pantyhose or others. It will be found some other new forms to use this contraction of the skin.
*********

Claims

We Claim:
1. We claim any kind of l)Protein, 2)Collagen, 3)Gelatin, 4) Amino acids
and 5)Salt[sodium chloride] itself or combine any from this 1) to 5)
substances in any combination or % from every substance is a remedy
for Anti-ageing and Anti-wrinkle to the skin.
2. We claim any kind of l)protein, 2)collagen, 3)gelatin, 4)amino acids
and 5)Salt[sodium chloride] itself or combine any from this 1) to 5)
substances in any combination or % from every substance is a remedy
for wound-healing and Wound-dressing, its stimulate a instant grow
to the proteins(any blood- or tissue-cells/protein) and cover the wound with a breathing skin.
3. We claim any kind of l)protein, 2)collagen, 3)gelatin, 4)amino acids
and 5)Salt[sodium chloride] itself or combine any from this 1 ) to 5) substances in any combination or % from every substance cause a contraction of the skin up to shape the body-form new, it can contract up to 8cm around the body.
4. We claim any kind of l)protein, 2)collagen, 3)gelatin, 4)amino acids
and 5)Salt[sodium chloride] itself or combine any from this 1) to 5)
substances in any combination or % from every substance light up the
skin/the pigmentation(the skin lights up and get shiny).
5. According to claim 1&2&3&4 to the 1) to 5) substances can be in any form: liquid form or as powder- or as granulate- or in solid-form; the form don't make any difference.
6. According to claim 1 &2&4 in any combination or % of
the substances 1) to 5) is one treatment visible and holding up
between 2 to 60 days the Anti-ageing and Anti-wrinkle from the skin
and the contraction & lighten up of the skin.
7. According to claim 1&2&3&4 it can be used in any combination or % from this 1) to 5) Substances or one itself, combined in/with any cosmetic or medical carrier/transporter in chemical or biological form, in liquid- or powder- or granulate- or solid- or cream- or spray-form.
8. According to claim 1&2 the substances 1) to 5) can be used as healing remedy for skin-illness.
9. According to claim 1&3&4 the substances 1) to 5) is preventing our skin from
pollution of the environment.
10. According to claim 1&2&3&4 it can be used by humans and animals/pets.
11. According to claim 1&2&3& 4 it can be combined with any other substances.
12. According to claim 3 it can shrink the visibility of cellulite to zero% or nil.
********
PCT/AU2009/000963 2009-07-30 2009-07-30 A cosmetic composition comprising sodium chloride in combination with one or more of protein, collagen, gelatin or amino acid WO2011011808A1 (en)

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PCT/AU2009/000963 WO2011011808A1 (en) 2009-07-30 2009-07-30 A cosmetic composition comprising sodium chloride in combination with one or more of protein, collagen, gelatin or amino acid

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WO2011011808A1 true WO2011011808A1 (en) 2011-02-03
WO2011011808A8 WO2011011808A8 (en) 2011-07-21

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011055800A1 (en) * 2011-11-29 2013-05-29 Gelita Ag Use of collagen hydrolyzate for treating and/or preventing cellulite, and as food supplement
EP2785420B1 (en) * 2011-11-29 2018-03-14 Gelita AG Cosmetic use of collagen hydrolysate

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WO1999060951A1 (en) * 1998-05-22 1999-12-02 Isolagen Technologies, Inc. Compositions for regenerating tissue that has degenerated, and methods for using such compositions
WO2000007465A1 (en) * 1998-08-03 2000-02-17 Toh-Men Co., Ltd. Solution for resuscitating multicellular organism cells and method for resuscitating multicellular organism cells by using the same
WO2000072872A1 (en) * 1999-06-02 2000-12-07 Human Genome Sciences, Inc. Keratinocyte growth factor-2 formulations
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WO2005010282A1 (en) * 2003-07-25 2005-02-03 Bridgest0Ne Corporation Icebreaker and waterway with icebreaker
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WO2005067867A1 (en) * 2004-01-20 2005-07-28 Kose Corporation Cosmetic
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WO2006015675A1 (en) * 2004-08-04 2006-02-16 Henkel Kommanditgesellschaft Auf Aktien Skin-cosmetic preparation based on multi- unsaturated fats
US20070154424A1 (en) * 2005-01-19 2007-07-05 Kose Corporation Cosmetic
WO2008082525A1 (en) * 2006-12-19 2008-07-10 National Stem Cell Inc Umbilical cord stem cell secreted product derived topical compositions and methods of use thereof
WO2009016629A2 (en) * 2007-07-30 2009-02-05 Healor Ltd. Pharmaceutical composition for treating wounds and related methods
US20090105336A1 (en) * 2004-04-19 2009-04-23 Strategic Science & Technologies, Llc Beneficial Effects of Increasing Local Blood Flow
US20090131537A1 (en) * 2007-11-14 2009-05-21 Wille Jr John Jacob Wound healing compositions

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0385155A2 (en) * 1989-02-21 1990-09-05 Klein, Peter, Prof.Dr.med. Cosmetic preparation for skin treatment
US20020041903A1 (en) * 1997-09-17 2002-04-11 Eric T. Fossel Topical delivery of arginine of cause beneficial effects
WO1999060951A1 (en) * 1998-05-22 1999-12-02 Isolagen Technologies, Inc. Compositions for regenerating tissue that has degenerated, and methods for using such compositions
US6432710B1 (en) * 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
WO2000007465A1 (en) * 1998-08-03 2000-02-17 Toh-Men Co., Ltd. Solution for resuscitating multicellular organism cells and method for resuscitating multicellular organism cells by using the same
WO2000072872A1 (en) * 1999-06-02 2000-12-07 Human Genome Sciences, Inc. Keratinocyte growth factor-2 formulations
WO2002000272A2 (en) * 2000-06-29 2002-01-03 Biosyntech Canada Inc. Composition and method for the repair and regeneration of cartilage and other tissues
JP2002308783A (en) * 2001-04-13 2002-10-23 Geo Co Ltd Medicinal composition for preventing and treating skin or mucous membrane disease
WO2003005979A2 (en) * 2001-07-07 2003-01-23 Beiersdorf Ag Cosmetic and dermatological preparations containing osmolytes for the treatment and active prevention of dry skin and of other negative alterations in the physiological homeostasis of healthy skin
US20040265268A1 (en) * 2001-08-18 2004-12-30 Deepak Jain Compositions and methods for skin rejuvenation and repair
WO2005010282A1 (en) * 2003-07-25 2005-02-03 Bridgest0Ne Corporation Icebreaker and waterway with icebreaker
FR2864445A1 (en) * 2003-12-30 2005-07-01 Jean Noel Thorel Use of a complex nutrient medium for skin treatment in humans and animals, e.g. for regenerating skin and promoting wound healing, which is free of growth factors and untraceable animal or cellular products
WO2005067867A1 (en) * 2004-01-20 2005-07-28 Kose Corporation Cosmetic
US20090105336A1 (en) * 2004-04-19 2009-04-23 Strategic Science & Technologies, Llc Beneficial Effects of Increasing Local Blood Flow
US20050277568A1 (en) * 2004-06-14 2005-12-15 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Fibrous elastic gel cleansing article
WO2006015675A1 (en) * 2004-08-04 2006-02-16 Henkel Kommanditgesellschaft Auf Aktien Skin-cosmetic preparation based on multi- unsaturated fats
US20070154424A1 (en) * 2005-01-19 2007-07-05 Kose Corporation Cosmetic
WO2008082525A1 (en) * 2006-12-19 2008-07-10 National Stem Cell Inc Umbilical cord stem cell secreted product derived topical compositions and methods of use thereof
WO2009016629A2 (en) * 2007-07-30 2009-02-05 Healor Ltd. Pharmaceutical composition for treating wounds and related methods
US20090131537A1 (en) * 2007-11-14 2009-05-21 Wille Jr John Jacob Wound healing compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011055800A1 (en) * 2011-11-29 2013-05-29 Gelita Ag Use of collagen hydrolyzate for treating and/or preventing cellulite, and as food supplement
EP2785420B1 (en) * 2011-11-29 2018-03-14 Gelita AG Cosmetic use of collagen hydrolysate

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