WO2011140274A3 - Method and device for transdermal delivery of parathyroid hormone using a microprojection array - Google Patents
Method and device for transdermal delivery of parathyroid hormone using a microprojection array Download PDFInfo
- Publication number
- WO2011140274A3 WO2011140274A3 PCT/US2011/035261 US2011035261W WO2011140274A3 WO 2011140274 A3 WO2011140274 A3 WO 2011140274A3 US 2011035261 W US2011035261 W US 2011035261W WO 2011140274 A3 WO2011140274 A3 WO 2011140274A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- parathyroid hormone
- transdermal delivery
- microprojection array
- array
- pth
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2011248108A AU2011248108B2 (en) | 2010-05-04 | 2011-05-04 | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
EP11778302.7A EP2566501B1 (en) | 2010-05-04 | 2011-05-04 | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
CA2798145A CA2798145C (en) | 2010-05-04 | 2011-05-04 | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
ES11778302T ES2719595T3 (en) | 2010-05-04 | 2011-05-04 | Method and device for transdermal administration of parathyroid hormone using a microprojection matrix |
JP2013509240A JP6327852B2 (en) | 2010-05-04 | 2011-05-04 | Methods and devices for transdermal delivery of parathyroid hormone using microprojection arrays |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33122610P | 2010-05-04 | 2010-05-04 | |
US61/331,226 | 2010-05-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011140274A2 WO2011140274A2 (en) | 2011-11-10 |
WO2011140274A3 true WO2011140274A3 (en) | 2012-04-05 |
Family
ID=44902423
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2011/035261 WO2011140274A2 (en) | 2010-05-04 | 2011-05-04 | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
Country Status (7)
Country | Link |
---|---|
US (4) | US9687641B2 (en) |
EP (1) | EP2566501B1 (en) |
JP (2) | JP6327852B2 (en) |
AU (1) | AU2011248108B2 (en) |
CA (1) | CA2798145C (en) |
ES (1) | ES2719595T3 (en) |
WO (1) | WO2011140274A2 (en) |
Cited By (2)
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US9114238B2 (en) | 2007-04-16 | 2015-08-25 | Corium International, Inc. | Solvent-cast microprotrusion arrays containing active ingredient |
US9498524B2 (en) | 2007-04-16 | 2016-11-22 | Corium International, Inc. | Method of vaccine delivery via microneedle arrays |
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AU2011248108B2 (en) * | 2010-05-04 | 2016-05-26 | Corium Pharma Solutions, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
PT2568806T (en) | 2010-05-12 | 2016-08-05 | Radius Health Inc | Therapeutic regimens |
JP5965909B2 (en) | 2010-09-28 | 2016-08-10 | ラジウス ヘルス,インコーポレイテッド | Selective androgen receptor modulator |
EP2764887B1 (en) | 2011-10-06 | 2020-12-02 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
KR102143435B1 (en) | 2011-11-30 | 2020-08-11 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | Microneedle device including a peptide therapeutic agent and an amino acid and methods of making and using the same |
JP6237621B2 (en) * | 2012-06-22 | 2017-11-29 | 凸版印刷株式会社 | Needle-like body and method for producing needle-like body |
RU2698095C2 (en) | 2012-12-21 | 2019-08-22 | Кориум Интернэшнл, Инк. | Microarray for therapeutic agent delivery and methods of using |
KR102295456B1 (en) | 2013-02-28 | 2021-08-27 | 소렌토 쎄라퓨틱스, 인코포레이티드 | Transdermal drug delivery device |
US10668260B2 (en) * | 2013-03-12 | 2020-06-02 | Takeda Pharmaceutical Company Limited | Microneedle patch |
CN105142711B (en) | 2013-03-12 | 2019-01-22 | 考里安国际公司 | Micro-protuberance applicator |
EP2968116A1 (en) | 2013-03-15 | 2016-01-20 | Corium International, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
JP6700170B2 (en) * | 2013-03-15 | 2020-05-27 | コリウム, インコーポレイテッド | Microarrays for delivery of therapeutic agents and methods of use |
BR112015022432B1 (en) | 2013-03-15 | 2022-02-15 | Corium, Inc | MICROSTRUCTURE ARRANGEMENT, METHOD FOR MANUFACTURING IT AND LIQUID FORMULATION TO FORM DISSOLUTION MICROSTRUCTURES |
ES2761580T3 (en) * | 2013-03-15 | 2020-05-20 | Corium Inc | Microarrays for therapeutic agent delivery, methods of use and manufacturing methods |
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JP6481613B2 (en) * | 2013-07-22 | 2019-03-13 | 凸版印刷株式会社 | Microneedle and method for manufacturing microneedle |
EP3111987B1 (en) * | 2014-02-27 | 2022-04-20 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle sheet |
ES2944885T3 (en) | 2014-08-29 | 2023-06-26 | Corium Pharma Solutions Inc | Matrix of microstructures for administration of active agents |
US10624843B2 (en) | 2014-09-04 | 2020-04-21 | Corium, Inc. | Microstructure array, methods of making, and methods of use |
MA41818A (en) * | 2015-03-27 | 2018-01-30 | Leo Pharma As | MICRO-NEEDLE STAMP FOR ADMINISTRATION OF AN ACTIVE SUBSTANCE TO THE SKIN |
IL255148B2 (en) | 2015-04-29 | 2023-04-01 | Radius Pharmaceuticals Inc | Rad 1901 for use in a method of inhibiting tumor growth or producing tumor regression in a subject having a drug-resistant and/or mutant estrogen receptor alpha-positive cancer |
US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
JPWO2017018086A1 (en) * | 2015-07-29 | 2018-02-01 | Nissha株式会社 | Micro needle seat |
JP6799005B2 (en) * | 2015-12-15 | 2020-12-09 | 久光製薬株式会社 | Microneedle sheet |
US20170348218A1 (en) * | 2016-06-03 | 2017-12-07 | Sanova Bioscience Inc | Microneedle patch containing hyaluronic acid for cosmetic use |
ES2913470T3 (en) | 2016-06-22 | 2022-06-02 | Ellipses Pharma Ltd | AR+ breast cancer treatment methods |
CA3046799A1 (en) * | 2016-12-16 | 2018-06-21 | Sorrento Therapeutics, Inc. | Fluid delivery apparatus and method of assembly |
AU2017378040B2 (en) | 2016-12-16 | 2023-06-08 | Sorrento Therapeutics, Inc. | Application device for a fluid delivery apparatus and method of use |
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WO2018111621A1 (en) | 2016-12-16 | 2018-06-21 | Kimberly-Clark Worldwide, Inc. | A fluid delivery apparatus having a controller assembly and method of use |
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US11219721B2 (en) | 2016-12-16 | 2022-01-11 | Sorrento Therapeutics, Inc. | Attachment band for a fluid delivery apparatus and method of use |
KR102322802B1 (en) | 2017-01-05 | 2021-11-04 | 래디어스 파마슈티컬스, 인코포레이티드 | Polymorphic form of RAD1901-2HCL |
KR101776659B1 (en) * | 2017-02-27 | 2017-09-11 | 주식회사 쿼드메디슨 | Micro-needles and methof of mamufacture |
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AU2019297421A1 (en) | 2018-07-04 | 2021-01-28 | Radius Pharmaceuticals, Inc. | Polymorphic forms of RAD 1901-2HCL |
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US20230073125A1 (en) * | 2019-10-29 | 2023-03-09 | The Regents Of The University Of California | Periodontal micropatch and uses thereof |
WO2023022217A1 (en) * | 2021-08-20 | 2023-02-23 | コスメディ製薬株式会社 | High-performance microneedle array |
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2011
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- 2011-05-04 ES ES11778302T patent/ES2719595T3/en active Active
- 2011-05-04 CA CA2798145A patent/CA2798145C/en active Active
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2016
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Also Published As
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CA2798145C (en) | 2022-10-18 |
EP2566501A2 (en) | 2013-03-13 |
AU2011248108B2 (en) | 2016-05-26 |
JP2017019785A (en) | 2017-01-26 |
JP6327852B2 (en) | 2018-05-23 |
US9687641B2 (en) | 2017-06-27 |
CA2798145A1 (en) | 2011-11-10 |
WO2011140274A2 (en) | 2011-11-10 |
AU2011248108A1 (en) | 2012-12-13 |
JP2013527853A (en) | 2013-07-04 |
US20200405630A1 (en) | 2020-12-31 |
ES2719595T3 (en) | 2019-07-11 |
EP2566501A4 (en) | 2014-04-16 |
US20230027289A1 (en) | 2023-01-26 |
US20110276028A1 (en) | 2011-11-10 |
EP2566501B1 (en) | 2019-03-13 |
JP6279662B2 (en) | 2018-02-14 |
US11419816B2 (en) | 2022-08-23 |
US20170281535A1 (en) | 2017-10-05 |
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